Results 31 to 40 of about 8,234 (175)

Identification of Steroidal Alkaloids with In Vitro Antiprotozoal Activity from Holarrhena pubescens Wall. ex G. Don

Molecules
Human African Trypanosomiasis (HAT) and Malaria are serious infectious diseases endemic in tropical regions, caused by protozoan parasites, and necessitating an urgent development of new antiprotozoal drugs.
Justus Wambua Mukavi, Monica Cal, Marcel Kaiser, Pascal Mäser, Njogu M. Kimani, Leonidah Kerubo Omosa, Thomas J. Schmidt   +6 more
doaj   +1 more source

Physicochemical Characterization and Biological activities of Sulfated Polysaccharides from Cultivated Rhodophyta

Natural Product Communications, 2017
Crude and alkali treated carrageenan from the cultivated marine alga Solieria filiformis (Rhodophyta) were obtained, characterized and evaluated for their cytotoxic and antiprotozoal activities.
Edgar Caamal-Fuentes, Daniel Robledo, Yolanda Freile-Pelegrín   +2 more
doaj   +1 more source

A comprehensive phytochemical and pharmacological review on sesquiterpenes from the genus Ambrosia

Heliyon, 2022
Sesquiterpenes are bitter secondary metabolites characteristic to the genus Ambrosia (Asteraceae) and constitute one of the most diverse classes of terpenoids.
Balázs Kovács, Judit Hohmann, Boglárka Csupor-Löffler, Tivadar Kiss, Dezső Csupor   +4 more
doaj   +1 more source

Pharmacokinetics of Diclazuril in the Plasma and Cerebrospinal Fluid of Healthy Adult Horses After a Single Oral Dose Administered as a Pelleted Topdressing

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT Equine protozoal myeloencephalitis can cause acute infections with rapid onset of neurologic signs, necessitating immediate empiric therapy with antiprotozoal medication. The objective of the study was to identify when concentrations of diclazuril reached the MIC of Sarcocystis neurona in CSF (1 ng/mL) of healthy adult horses after a single ...
Elizabeth J. Treece, Kate L. Hepworth‐Warren, Mark G. Papich, Philip D. van Harreveld, Anthony T. Blikslager, Faith E. Church, Kaitlyn B. Harbor, Sara J. Erwin‐Craig   +7 more
wiley   +1 more source

HPLC-Based Activity Profiling for Antiprotozoal Compounds in Croton gratissimus and Cuscuta hyalina

Frontiers in Pharmacology, 2020
In a screening of Sudanese medicinal plants for antiprotozoal activity, the chloroform fractions obtained by liquid-liquid partitioning from ethanolic extracts of fruits of Croton gratissimus var.
Abdelhalim Babiker Mahmoud, Abdelhalim Babiker Mahmoud, Abdelhalim Babiker Mahmoud, Ombeline Danton, Marcel Kaiser, Marcel Kaiser, Sami Khalid, Sami Khalid, Matthias Hamburger, Pascal Mäser, Pascal Mäser   +10 more
doaj   +1 more source

Discovery of Ircinianin Lactones B and C—Two New Cyclic Sesterterpenes from the Marine Sponge Ircinia wistarii

Marine Drugs, 2022
Two new ircinianin-type sesterterpenoids, ircinianin lactone B and ircinianin lactone C (7 and 8), together with five known entities from the ircinianin compound family (1, 3–6) were isolated from the marine sponge Ircinia wistarii. Ircinianin lactones B
Thomas Majer, Keshab Bhattarai, Jan Straetener, Justus Pohlmann, Patrick Cahill, Markus O. Zimmermann, Marc P. Hübner, Marcel Kaiser, Johan Svenson, Michael Schindler, Heike Brötz-Oesterhelt, Frank M. Boeckler, Harald Gross   +12 more
doaj   +1 more source

Antiprotozoal and antimycobacterial activities of Persea americana seeds [PDF]

BMC Complementary and Alternative Medicine, 2013
Persea americana seeds are widely used in traditional Mexican medicine to treat rheumatism, asthma, infectious processes as well as diarrhea and dysentery caused by intestinal parasites.The chloroformic and ethanolic extracts of P. americana seeds were prepared by maceration and their amoebicidal, giardicidal and trichomonicidal activity was evaluated.
Jiménez-Arellanes, Adelina, Luna-Herrera, Julieta, Ruiz-Nicolás, Ricardo, Cornejo-Garrido, Jorge, Tapia, Amparo, Yépez-Mulia, Lilián   +5 more
openaire   +2 more sources

Efficacy of 0.2% povidone‐iodine and 0.1% polyhexamethylene biguanide as preoperative antiseptics in equine ophthalmic procedures

Veterinary Ophthalmology, Volume 28, Issue 2, Page 438-447, March 2025.
Abstract Objective This retrospective study evaluates the efficacy of povidone‐iodine (PI) and polyhexamethylene biguanide (PHMB) as preoperative antiseptics in equine ophthalmic procedures. Animals Studied Horses that underwent routine ophthalmic surgery and procedures.
Anna Farkas, Katharina Thieme, Tanawan Soimala, Charlotte K. Jensen, J. Corinna Eule   +4 more
wiley   +1 more source

Antiprotozoal Activity of Sesquiterpenes from Jasonia Glutinosa [PDF]

Pharmaceutical Biology (Formerly International Journal of Pharmacognosy), 2000
Two sesquiterpene alcohols, [11 R]-eudesm-4(14)-en-5ß,11,12-triol ( 1 ) and [11R]-eudesm-4(14)-en-5a,11-12-triol ( 2 ), from Jasonia glutinosa aerial parts (Asteraceae), have been tested using an in vitro technique against Leishmania donovani (promastigote forms) and Plasmodium falciparum .
L, Villaescusa-Castillo, A M, Díaz-Lanza, M, Gasquet, F, Delmas, E, Ollivier, M, Bernabé, R, Faure, R, Elias, G, Balansard   +8 more
openaire   +2 more sources

hERG1 channels and potential therapeutics for long QT syndrome

The Journal of Physiology, EarlyView.
Abstract figure legend Prolonged QT results from hERG1 channel dysfunction. (A) Physiological anterograde trafficking of hERG1 channels to the plasma membrane, leading to a normal electrocardiogram. (B) Prolonged QT results from the presence of fewer hERG1 channels on the plasma membrane due to decreased anterograde trafficking or reduced function due ...
Elizabeth H. Schneider, Kelly A. Aromolaran, Michael C. Sanguinetti, Ademuyiwa S. Aromolaran   +3 more
wiley   +1 more source