Results 51 to 60 of about 8,234 (175)

Identification of Antiprotozoal Compounds from Buxus sempervirens L. by PLS-Prediction

Molecules, 2021
Various nor-triterpene alkaloids of Buxus (B.) sempervirens L. have shown remarkable in vitro activity against the causative agents of tropical malaria and East African sleeping sickness.
Lara U. Szabó, Marcel Kaiser, Pascal Mäser, Thomas J. Schmidt   +3 more
doaj   +1 more source

Exploring the Factors Influencing the Non‐Prescription Use of Medication in Bangladesh: A Cross‐Sectional Study

Health Science Reports, Volume 9, Issue 7, July 2026.
ABSTRACT Background and Aims Use of non‐prescription drugs is a significant health concern for the population in Bangladesh. The ease of access to medicines, the high price of healthcare and lack of information on how to take the drugs properly promote such a practice.
Sumaia Rahman, S. M. Mahadi Hasan, Md. Omar Faruk, Md. Aminul Islam Nur, Mst. Hajera Khatun   +4 more
wiley   +1 more source

Antiprotozoal Activities of Organic Extracts from French Marine Seaweeds

Marine Drugs, 2011
Marine macrophytes contain a variety of biologically active compounds, some reported to have antiprotozoal activity in vitro. As a part of a screening program to search for new natural antiprotozoals, we screened hydroalcoholic and ethyl acetate extracts
Antoine Vastel, Isabelle Mussio, Anne-Marie Rusig, Isabelle Devambez, Marcel Kaiser, Catherine Vonthron-Sénécheau   +5 more
doaj   +1 more source

Clinical and Diagnostic Considerations in Laryngeal Leishmaniasis: A Systematic Review

OTO Open, Volume 10, Issue 3, July-September 2026.
Abstract Objective Laryngeal leishmaniasis is a rare, insidious manifestation of Leishmania infection with potential for life‐threatening complications. Awareness is critical for efficient and timely diagnosis. This systematic review of laryngeal leishmaniasis focuses on presentation, treatment, and the role of serological studies in the work up of ...
Joseph Celidonio, Nicholas Hamilton, Alexandra Filipkowski, Raj Malhotra, Samantha Shave, Myat E. Mon, Kenneth Yan, Rachel Kaye   +7 more
wiley   +1 more source

Flavonoids in Nasal Therapeutics: Biological Activities, Delivery Challenges, and Formulation Strategies–A Systematic Review

Phytotherapy Research, Volume 40, Issue 7, Page 4676-4709, July 2026.
Overview of the therapeutic potential of flavonoids in nasal delivery systems, highlighting their benefits to the human nasal cavity, and applications in the treatment of respiratory and brain‐related diseases. ABSTRACT Flavonoids represent a significant group of secondary metabolites.
Jeniffer Viviana Ramirez Hernández, Sara Elis Bianchi, Flávia Nathiely Silveira Fachel, Elizandra Braganhol, Sheila Porto de Matos, Valquíria Linck Bassani   +5 more
wiley   +1 more source

Evaluation of the Utilization Pattern of Veterinary Drugs in Selected Veterinary Clinics of Mekelle City, Tigray, Ethiopia

Veterinary Medicine and Science, Volume 12, Issue 4, July 2026.
Veterinary drug utilization patterns were assessed in three veterinary clinics in Mekelle City, Ethiopia. Antimicrobials, particularly oxytetracycline, constitute the majority of prescriptions, followed by anthelmintics. Drug prescribing frequently relies on tentative diagnosis rather than evidence‐based diagnostic procedures.
Helen Hagos, Mebrahtu Weldegebriel, Hagazi Fantay, Haftom Yirga Tsegay   +3 more
wiley   +1 more source

Antiprotozoal activity of Melampyrum arvense and its metabolites [PDF]

Phytotherapy Research, 2010
AbstractAn activity guided isolation of the H2O subextract of the crude extract of Melampyrum arvense L. afforded iridoid glucosides: aucubin (1), melampyroside (2), mussaenoside (3), mussaenosidic acid (4), 8‐epi‐loganin (5); flavonoids: apigenin (6), luteolin (7), luteolin 7‐O‐β‐glucopyranoside (8); a lignan glycoside dehydrodiconiferyl alcohol 9‐O‐β‐
Kirmizibekmez, H., Atay, I., Kaiser, M., Brun, R., Cartagena, M. M., Carballeira, N. M., Yesilada, E., Tasdemir, D.   +7 more
openaire   +4 more sources

Blood Protozoan Infection Disrupts Ovarian Follicular Development in Dairy Cattle: A Mechanistic Link to Reproductive Failure

Veterinary Medicine and Science, Volume 12, Issue 4, July 2026.
Subclinical haemoprotozoan infection disrupts RBC integrity, and that leads to decreased Hb level and excess free iron in plasma. That subsequently impairs ovarian follicular development and thereby builds up a mechanistic link to reproductive failure in dairy cattle.
Most. Mousumi Akter, Md. Sadequl Islam, Md. Ashraful Islam, Md. Mahmudul Hasan, Rakibul Islam, Md. Mominul Islam, Md. Gausur Rahman, Md. Shafiqul Islam, Anup Kumar Talukder, Md. Bazlar Rashid   +9 more
wiley   +1 more source

Antiprotozoal peptide prediction using machine learning with effective feature selection techniques

Heliyon
Background: Protozoal pathogens pose a considerable threat, leading to notable mortality rates and the ongoing challenge of developing resistance to drugs. This situation underscores the urgent need for alternative therapeutic approaches.
Neha Periwal, Pooja Arora, Ananya Thakur, Lakshay Agrawal, Yash Goyal, Anand S. Rathore, Harsimrat Singh Anand, Baljeet Kaur, Vikas Sood   +8 more
doaj   +1 more source

Synthesis, Characterization, Molecular Docking Study and Biological Evaluation of Novel 1,3,4‐Thiadiazole‐Based Heterocycles as Potential Anticancer and Antioxidant Agents

Chemical Biology &Drug Design, Volume 108, Issue 1, July 2026.
A new cyanoacetohydrazide derivative was developed as a key intermediate to synthesize diverse 1,3,4‐thiadiazole‐based heterocyclic compounds. The synthesized compounds were structurally confirmed. Several compounds demonstrated strong cytotoxic activity against HePG‐2 and MCF‐7 cancer cell lines, with compounds 17, 18, and 13 exceeding the activity of
Nashwa M. El‐Metwaly, Abdulmajeed F. Alrefaei, Hossa F. Alshareef, Samar J. Almehmadi, Fatimah A. Alotaibi, Nadiyah M. Alshammari, Manal S. Ebaid, Hanadi A. Katouah   +7 more
wiley   +1 more source