Results 71 to 80 of about 16,319 (219)

Antiprotozoal and molluscicidal activities of five Brazilian plants [PDF]

Brazilian Journal of Medical and Biological Research, 2005
Leishmaniasis, Chagas' disease and schistosomiasis (bilharzia) are parasitic diseases with wide distribution on the American continent, affecting millions of people. In the present study, biological assays for antiprotozoal and molluscicidal activities were carried out with ethanolic extracts of plant species from the Brazilian part of the Upper Paraná
Truiti, M.C.T., Ferreira, I.C.P., Zamuner, M.L.M., Nakamura, C.V., Sarragiotto, M.H., Souza, M.C.   +5 more
openaire   +6 more sources

Evaluation of in vitro antiprotozoal activity of Ajuga laxmannii and its secondary metabolites [PDF]

, 2016
: Context: Some Ajuga L. (Lamiaceae) species are traditionally used for the treatment of malaria, as well as fever, which is a common symptom of many parasitic diseases.
Akaydin, Galip, Atay, Irem, Kaiser, Marcel, Kirmizibekmez, Hasan, Tasdemir, Deniz, Yesilada, Erdem   +5 more
core   +1 more source

Effectiveness of Storing Medicinal Plant Leaves Under Modified Atmosphere on the Physicochemical Stability and Essential Oil Composition Over Time

New Zealand Journal of Crop and Horticultural Science, Volume 54, Issue 1, March 2026.
This study investigated the effects of packaging methods and storage time on the postharvest conservation of Lippia origanoides and Ocimum gratissimum. The research analyzed CO2 concentration inside the packaging, water content, color parameters (L*, a*, b*, C*, and ΔE*), essential oil content, and chromatographic composition of the essential oil ...
Cristiane F. Lisboa, Evandro C. Melo, Antônio J. Demuner, Luís C. da Silva, Antônio P. S. Carneiro, Ana Paula F. Coelho, Ailyn de O. Vilela, Naiara C. Z. Sperotto   +7 more
wiley   +1 more source

Antileishmanial and trypanocidal activity of brazilian Cerrado plants [PDF]

, 2005
The side effects and the emerging resistance to the available drugs against leishmaniasis and trypanosomiasis led to the urgent need for new therapeutic agents against these diseases.
Bories, Christian, Desrivot, Julie, Espindola, Laila Salmen, Fournet, Alain, Grellier, Philippe, Mesquita, Mariana Laundry de, Paula, José Elias de   +6 more
core   +4 more sources

Prevalence of Intestinal Parasitic Infections and Associated Factors Among Rural Ghanaian School Children: A Cross‐Sectional Study in Tokuroano, Krachi East Municipality

Public Health Challenges, Volume 5, Issue 1, March 2026.
Over 63% of schoolchildren in rural Ghana's Tokuroano area had intestinal parasitic infections, mainly Ascaris, Hookworm, and Giardia. Poor sanitation, unsafe water, and poor hygiene were key risks. Protective factors included home‐cooked meals and health education. Integrated deworming, sanitation, and education programs are urgently needed to address
Christopher Yaw Dumevi, Prince Wise Amekudi, Nana Aba Setorwu Eyeson, Hugette Naa Ayele Aryee, Joyce Junior Asiamah, Ezekiel Kofi Vicar, James‐Paul Kretchy, Simon Sovoe, Saviour Kweku Adjenti, Nicholas T. K. D. Dayie, George Boateng Kyei, Patience B. Tetteh‐Quarcoo, Irene Ayi, Patrick F. Ayeh‐Kumi   +13 more
wiley   +1 more source

Activity of benzimidazoles against Dientamoeba fragilis (Trichomonadida, Monocercomonadidae) in vitro and correlation of beta-tubulin sequences as an indicator of resistance [PDF]

, 2014
Recently, Dientamoeba fragilis has emerged as a significant and common enteropathogen. The majority of patients with dientamoebiasis present with gastrointestinal complaints and chronic symptoms are common. Numerous studies have successfully demonstrated
Barratt, JLN, Ellis, J, Harkness, JT, Marriott, D, Roberts, T, Stark, D   +5 more
core   +1 more source

Identifying Drugs Associated With Parkinson's Disease Risk Using Machine Learning

Basic &Clinical Pharmacology &Toxicology, Volume 138, Issue 3, March 2026.
ABSTRACT Machine learning (ML)–based methods have been proposed as a potential approach for identifying candidate drugs to be repurposed as disease‐modifying treatments for Parkinson's disease (PD). We applied an ML‐based signal detection method to identify drugs associated with PD and evaluated the method's generalizability.
Eeva Pylkkö, Émeline Courtois, Anne Paakinaho, Sirpa Hartikainen, Valtteri Kaasinen, Alexis Elbaz, Anne C. M. Thiébaut, Ismaïl Ahmed, Anna‐Maija Tolppanen   +8 more
wiley   +1 more source

Management of Haws Syndrome in Cats With Gastrointestinal Diet: A Case Series

Veterinary Ophthalmology, Volume 29, Issue 2, March 2026.
ABSTRACT Background Haws syndrome (HS) in cats is characterized by bilateral protrusion of the third eyelid and ptosis, often accompanied by gastrointestinal (GI) symptoms such as diarrhea. Emerging evidence suggests disruption of the gut‐brain axis, linked to GI microbiota dysbiosis, may play a role in HS development.
Bar Fruchter, Sharon Kuzi, Yamit Soueid, Oren Pe'er, Ron Ofri, Lionel Sebbag   +5 more
wiley   +1 more source

Antiprotozoal peptide prediction using machine learning with effective feature selection techniques

Heliyon
Background: Protozoal pathogens pose a considerable threat, leading to notable mortality rates and the ongoing challenge of developing resistance to drugs. This situation underscores the urgent need for alternative therapeutic approaches.
Neha Periwal, Pooja Arora, Ananya Thakur, Lakshay Agrawal, Yash Goyal, Anand S. Rathore, Harsimrat Singh Anand, Baljeet Kaur, Vikas Sood   +8 more
doaj   +1 more source

Antiprotozoal Activity and DNA Binding of Dicationic Acridones

Journal of Medicinal Chemistry, 2015
Dicationic acridone derivatives were synthesized and their antiparasitic activity was evaluated. Acridones displayed in vitro nanomolar IC50 values against Trypanosoma brucei rhodesiense STIB900 with selectivity indices >1000. Compounds 1b, 3a, and 3b were as potent as the reference drug melarsoprol in this assay.
Montalvo-Quirós, Sandra, Taladriz-Sender, Andrea, Kaiser, Marcel, Dardonville, Christophe   +3 more
openaire   +4 more sources