Results 21 to 30 of about 16,319 (219)

Antiprotozoal Activity against Entamoeba histolytica of Plants Used in Northeast Mexican Traditional Medicine. Bioactive Compounds from Lippia graveolens and Ruta chalepensis

Molecules, 2014
Amoebiasis caused by Entamoeba histolytica is associated with high morbidity and mortality is becoming a major public health problem worldwide, especially in developing countries.
Ramiro Quintanilla-Licea, Benito David Mata-Cárdenas, Javier Vargas-Villarreal, Aldo Fabio Bazaldúa-Rodríguez, Isvar Kavimngeles-Hernández, Jesús Norberto Garza-González, Magda Elizabeth Hernández-García   +6 more
doaj   +1 more source

Antiprotozoal Nor-Triterpene Alkaloids from Buxus sempervirens L.

Antibiotics, 2021
Malaria and human African trypanosomiasis (HAT; sleeping sickness) are life-threatening tropical diseases caused by protozoan parasites. Due to limited therapeutic options, there is a compelling need for new antiprotozoal agents.
Lara U. Szabó, Marcel Kaiser, Pascal Mäser, Thomas J. Schmidt   +3 more
doaj   +1 more source

Anti-Trypanosoma cruzi action of a new benzofuran derivative based on amiodarone structure [PDF]

, 2018
Chagas disease is a neglected tropical affection caused by the protozoan parasite Trypanosoma cruzi. There is no current effective treatment since the only two available drugs have a limited efficacy and produce side effects.
Benaim, Gustavo, Hejchman, Elżbieta, Hernández Rodríguez, Vanessa, Pinto Martinez, Andrea, Rodríguez Durán, Jessica Jenireth   +4 more
core   +1 more source

Synthesis of Jacaranone-Derived Nitrogenous Cyclohexadienones and Their Antiproliferative and Antiprotozoal Activities

Molecules, 2018
The cytotoxic and antiprotozoal activities of the phytoquinoide, jacaranone, and related compounds have been an ongoing topic in recent drug discovery. Starting from the natural product-derived cyclohexadienone scaffold, a series of nitrogen-containing ...
Armin Presser, Gunda Lainer, Nadine Kretschmer, Wolfgang Schuehly, Robert Saf, Marcel Kaiser, Marc-Manuel Kalt   +6 more
doaj   +1 more source

Antiparasitic activity of chicory (Cichorium intybus) and its natural bioactive compounds in livestock: a review [PDF]

, 2018
Increasing drug resistance in gastrointestinal (GI) parasites of livestock and concerns about chemical residues in animal products and the environment are driving the development of alternative control strategies that are less reliant on the use of ...
Boas, Ulrik, Enemark, Heidi L., López-Muñoz, Rodrigo, Peña-Espinoza, Miguel, Simonsen, Henrik T., Thamsborg, Stig M., Valente, Angela H., Williams, Andrew R.   +7 more
core   +4 more sources

Chemical Strategies towards the Synthesis of Betulinic Acid and Its More Potent Antiprotozoal Analogues

Molecules, 2021
Betulinic acid (BA, 3β-hydroxy-lup-20(29)-en-28-oic acid) is a pentacyclic triterpene acid present predominantly in Betula ssp. (Betulaceae) and is also widely spread in many species belonging to different plant families.
André Barreto Cunha, Ronan Batista, María Ángeles Castro, Jorge Mauricio David   +3 more
doaj   +1 more source

The Mediterranean Red Alga Asparagopsis: A Source of Compounds against Leishmania

Marine Drugs, 2009
Crude extracts and column fractions from the red algae Asparagopsis taxiformis and A. armata from the Strait of Messina (Italy) were screened for the production of antimicrobial compounds.
Marina Morabito, Mark T. Hamann, Laura Tedone, Giuseppa Genovese   +3 more
doaj   +1 more source

Correlation between secondary metabolites of Iris confusa Sealy and Iris pseudacorus L. and their newly explored antiprotozoal potentials

BMC Complementary Medicine and Therapies, 2023
Background In the last few decades, the use of plant extracts and their phytochemicals as candidates for the management of parasitic diseases has increased tremendously.
Passent M. Abdel-Baki, Moshera M. El-Sherei, Amal E. Khaleel, Essam Abdel-Sattar, Mohamed A. Salem, Mona M. Okba   +5 more
doaj   +1 more source

Antiprotozoal activities of Colombian plants

Journal of Ethnopharmacology, 2001
In our search for therapeutical alternatives for antiprotozoal chemotherapy, we collected a selection of 44 plants from western Colombia upon ethnopharmacological and chemotaxonomic considerations. Polar and apolar extracts of these species were examined for antimalarial activity using in vitro tests with two clones of Plasmodium falciparum ...
Weniger, B., Robledo, S., Arango, G.J., /Deharo, Eric, Aragon, R., Munoz, V., Callapa, J., Lobstein, A., Anton, R.   +8 more
openaire   +3 more sources

Electrochemical behavior of indolone-N-oxides: Relationship to structure and antiplasmodial activity [PDF]

, 2012
Indolone-N-oxides exert high parasiticidal activity at the nanomolar level in vitro against Plasmodiumfalciparum, the parasite responsible for malaria.
Fabre, Paul-Louis, Ibrahim, Hany, Montrose, Armelle, Nepveu, Françoise, Nguyen, Thi Hoang Yen, Perio, Pierre, Reybier, Karine   +6 more
core   +3 more sources