Results 11 to 20 of about 16,319 (219)

Antiprotozoal and Antitumor Activity of Natural Polycyclic Endoperoxides: Origin, Structures and Biological Activity

open access: yesMolecules, 2021
Polycyclic endoperoxides are rare natural metabolites found and isolated in plants, fungi, and marine invertebrates. The purpose of this review is a comparative analysis of the pharmacological potential of these natural products.
Valery M. Dembitsky   +4 more
doaj   +3 more sources

ANTIPROTOZOAL ACTIVITY OF EXTRACTS OF ELAEODENDRON TRICHOTOMUM (CELASTRACEAE). [PDF]

open access: yesAfr J Tradit Complement Altern Med, 2016
Background: Chagas disease, amebiasis, giardiasis and trichomoniasis represent a serious health problem in Latin America. The drugs employed to treat these illnesses produce important side effects and resistant strains have appeared. The present study was aimed to evaluate the antiprotozoal activity of leaves, stem bark and root bark of ...
Roca-Mézquita C   +8 more
europepmc   +5 more sources

Antiprotozoal Activity of Achillea ptarmica (Asteraceae) and Its Main Alkamide Constituents [PDF]

open access: yesMolecules, 2014
In the course of our ongoing screening of plants of the family Asteraceae for antiprotozoal activity, a CH2Cl2-extract from the flowering aerial parts of Achillea ptarmica L.
Julia B. Althaus   +3 more
doaj   +2 more sources

Efficient Oxidative Dearomatisations of Substituted Phenols Using Hypervalent Iodine (III) Reagents and Antiprotozoal Evaluation of the Resulting Cyclohexadienones against T. b. rhodesiense and P. falciparum Strain NF54

open access: yesMolecules, 2022
Quinones and quinols are secondary metabolites of higher plants that are associated with many biological activities. The oxidative dearomatization of phenols induced by hypervalent iodine(III) reagents has proven to be a very useful synthetic approach ...
Nina Scheiber   +5 more
doaj   +1 more source

Synthesis, In Silico Studies, Antiprotozoal and Cytotoxic Activities of Quinoline‐Biphenyl Hybrids [PDF]

open access: yes, 2020
This is the pre-peer reviewed version of the following article: Synthesis, In Silico Studies, Antiprotozoal and Cytotoxic Activities of Quinoline‐Biphenyl Hybrids, which has been published in final form at https://doi.org/10.1002/slct.201903835.
Carda, Miguel   +6 more
core   +1 more source

Trypanocidal and leishmanicidal activity of six limonoids [PDF]

open access: yes, 2020
Six limonoids [kotschyienone A and B (1, 2), 7-deacetylgedunin (3), 7-deacetyl-7-oxogedunin (4), andirobin (5) and methyl angolensate (6)] were investigated for their trypanocidal and leishmanicidal activities using bloodstream forms of Trypanosoma ...
A-E Hay   +30 more
core   +3 more sources

Novel Formula of Antiprotozoal Mixtures

open access: yesAntibiotics, 2022
Antimicrobial resistance (AMR) is becoming more common in both bacteria and pathogenic protozoa. Therefore, new solutions are being sought as alternatives to currently used agents.
Hubert Iwiński   +3 more
doaj   +1 more source

Antiprotozoal activities of marine polyether triterpenoids [PDF]

open access: yesBioorganic Chemistry, 2019
Chagas disease and leishmaniasis are tropical neglected diseases caused by kinetoplastids protozoan parasites of Trypanosoma and Leishmania genera, and a public health burden with high morbidity and mortality rates in developing countries. Among difficulties with their epidemiological control, a major problem is their limited and toxic treatments to ...
López Arencibia, Atteneri   +11 more
openaire   +4 more sources

Antiprotozoal Activity of Rubratoxin B [PDF]

open access: yesAntimicrobial Agents and Chemotherapy, 1973
Growth of Tetrahymena pyriformis HSM was inhibited by a concentration of 25 μg of rubratoxin B per ml of growth medium. The inhibitory effect of aflatoxin B 1 -rubratoxin B mixtures on growth of T. pyriformis was induced by rubratoxin B only.
openaire   +2 more sources

S100B inhibitor pentamidine attenuates reactive gliosis and reduces neuronal loss in a mouse model of Alzheimer's disease [PDF]

open access: yes, 2015
Among the different signaling molecules released during reactive gliosis occurring in Alzheimer’s disease (AD), the astrocytederived S100B protein plays a key role in neuroinflammation, one of the hallmarks of the disease.
Capoccia, Elena   +6 more
core   +5 more sources

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