Results 11 to 20 of about 8,234 (175)
Quantitative Structure ‒ Antiprotozoal Activity Relationships of Sesquiterpene Lactones
Molecules, 2009 Prompted by results of our previous studies where we found high activity of some sesquiterpene lactones (STLs) against Trypanosoma brucei rhodesiense (which causes East African sleeping sickness), we have now conducted a structure-(in-vitro)-activity ...
Reto Brun +4 more
doaj +3 more sources
Molecules, 2022 Quinones and quinols are secondary metabolites of higher plants that are associated with many biological activities. The oxidative dearomatization of phenols induced by hypervalent iodine(III) reagents has proven to be a very useful synthetic approach ...
Nina Scheiber +5 more
doaj +1 more source
GENOMIC, PROTEOMIC AND MOLECULAR MODEL ANALYSES OF TMP KINASE FROM SOME BLOODPARASITIC PROTOZOA. ONE-STEP FORWARD IN DEVELOPMENT OF BROAD SPECTRUM ANTIPROTOZOAL DRUGS [PDF]
Kafrelsheikh Veterinary Medical Journal, 2009 We had introduced TMP kinase as a new hopeful antiprotozoal drugtarget. We provided theoretical model for the eligibility of TMP kinasefrom Plasmodium falciparum as a new drug target and we confirmedour assumption by experimental trials based on ...
Yukio Kitade, Mahmoud Kandeel
doaj +1 more source
Novel Formula of Antiprotozoal Mixtures
Antibiotics, 2022 Antimicrobial resistance (AMR) is becoming more common in both bacteria and pathogenic protozoa. Therefore, new solutions are being sought as alternatives to currently used agents.
Hubert Iwiński +3 more
doaj +1 more source
Antiprotozoal activities of marine polyether triterpenoids [PDF]
Bioorganic Chemistry, 2019 Chagas disease and leishmaniasis are tropical neglected diseases caused by kinetoplastids protozoan parasites of Trypanosoma and Leishmania genera, and a public health burden with high morbidity and mortality rates in developing countries. Among difficulties with their epidemiological control, a major problem is their limited and toxic treatments to ...
Ana R. Díaz-Marrero +11 more
openaire +5 more sources
Molecules, 2014 Amoebiasis caused by Entamoeba histolytica is associated with high morbidity and mortality is becoming a major public health problem worldwide, especially in developing countries.
Ramiro Quintanilla-Licea +6 more
doaj +1 more source
Antiprotozoal Activity of Rubratoxin B [PDF]
Antimicrobial Agents and Chemotherapy, 1973 Growth of Tetrahymena pyriformis HSM was inhibited by a concentration of 25 μg of rubratoxin B per ml of growth medium. The inhibitory effect of aflatoxin B 1 -rubratoxin B mixtures on growth of T. pyriformis was induced by rubratoxin B only.
openaire +2 more sources
Molecules, 2018 The cytotoxic and antiprotozoal activities of the phytoquinoide, jacaranone, and related compounds have been an ongoing topic in recent drug discovery. Starting from the natural product-derived cyclohexadienone scaffold, a series of nitrogen-containing ...
Armin Presser +6 more
doaj +1 more source
Antiprotozoal Nor-Triterpene Alkaloids from Buxus sempervirens L.
Antibiotics, 2021 Malaria and human African trypanosomiasis (HAT; sleeping sickness) are life-threatening tropical diseases caused by protozoan parasites. Due to limited therapeutic options, there is a compelling need for new antiprotozoal agents.
Lara U. Szabó +3 more
doaj +1 more source
The Mediterranean Red Alga Asparagopsis: A Source of Compounds against Leishmania
Marine Drugs, 2009 Crude extracts and column fractions from the red algae Asparagopsis taxiformis and A. armata from the Strait of Messina (Italy) were screened for the production of antimicrobial compounds.
Marina Morabito +3 more
doaj +1 more source