Journal of Chemistry, 2021 Background. Benzoxazole derivatives have different biological activities. In pursuit of designing novel chemical entities with antiprotozoal and antimicrobial activities, benzoxazolyl aniline was utilized as a privileged scaffold of a series of (3 ...
Mohamed A. Abdelgawad +12 more
doaj +1 more source
Antiprotozoal Effect of Snake Venoms and Their Fractions: A Systematic Review
Pathogens, 2021 Background: Protozoal infection is a lingering public health issue of great concern, despite efforts to produce drugs and vaccines against it. Recent breakthrough research has discovered alternative antiprotozoal agents encompassing the use of snake ...
Zainab U. Abdullahi +3 more
doaj +1 more source
Anti-Trypanosoma cruzi action of a new benzofuran derivative based on amiodarone structure [PDF]
, 2018 Chagas disease is a neglected tropical affection caused by the protozoan parasite Trypanosoma cruzi. There is no current effective treatment since the only two available drugs have a limited efficacy and produce side effects.
Benaim, Gustavo +4 more
core +1 more source
Electrochemical behavior of indolone-N-oxides: Relationship to structure and antiplasmodial activity [PDF]
, 2012 Indolone-N-oxides exert high parasiticidal activity at the nanomolar level in vitro against Plasmodiumfalciparum, the parasite responsible for malaria.
Fabre, Paul-Louis +6 more
core +3 more sources
Molecules, 2014 Amoebiasis caused by Entamoeba histolytica is associated with high morbidity and mortality is becoming a major public health problem worldwide, especially in developing countries.
Ramiro Quintanilla-Licea +6 more
doaj +1 more source
Antiparasitic activity of chicory (Cichorium intybus) and its natural bioactive compounds in livestock: a review [PDF]
, 2018 Increasing drug resistance in gastrointestinal (GI) parasites of livestock and concerns about chemical residues in animal products and the environment are driving the development of alternative control strategies that are less reliant on the use of ...
Boas, Ulrik +7 more
core +4 more sources
Discovery and Evaluation of Thiazinoquinones as Anti-Protozoal Agents
Marine Drugs, 2013 Pure compound screening has identified the dioxothiazino-quinoline-quinone ascidian metabolite ascidiathiazone A (2) to be a moderate growth inhibitor of Trypanosoma brucei rhodesiense (IC50 3.1 μM) and Plasmodium falciparum (K1 dual drug resistant ...
Marcel Kaiser +4 more
doaj +1 more source
Anti-BioEn: An advanced framework for accurate bioactive agent classification based on hybrid models and graph feature encoding method [PDF]
BIO Web of ConferencesBioactive agents are compounds that have an influence on human beings, organs, or tissues. These agents, which might be found in both natural and synthetic chemicals, are able to interact with biological systems and produce a variety of therapeutic or ...
Shaon Shazzad Hossain +3 more
doaj +1 more source
Activity of Cuban Propolis Extracts on and
Natural Product Communications, 2011 In this paper we analyzed the antiprotozoal effects of eighteen Cuban propolis extracts (brown, red and yellow type) collected in different geographic areas, using Leishmania amazonensis (as a model of intracellular protozoa) and Trichomonas vaginalis ...
Lianet Monzote Fidalgo +7 more
doaj +1 more source
Marine pharmacology in 2009-2011: marine compounds with antibacterial, antidiabetic, antifungal, anti-inflammatory, antiprotozoal, antituberculosis, and antiviral activities; affecting the immune and nervous systems, and other miscellaneous mechanisms of action. [PDF]
, 2013 The peer-reviewed marine pharmacology literature from 2009 to 2011 is presented in this review, following the format used in the 1998–2008 reviews of this series.
A. D. Rodriguez +3 more
core +2 more sources