Results 1 to 10 of about 106,790 (296)
Biomolecules, 2022 The ventral tegmental area (VTA) in the ventral midbrain is the origin of the dopaminergic neurotransmission pathways. Although GABAA receptors and AKT-GSK3β signaling are involved in the pathophysiology of mental disorders and are modulated by ...
Shiyan Chen +3 more
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Frontiers in Cellular Neuroscience, 2022 Introduction: Neuroinflammation in the central nervous system, particularly the prefrontal cortex (PFC), plays a role in the pathogenesis of schizophrenia, which has been found to be associated with maternal immune activation (MIA).
Yueqing Su +9 more
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Real-World Functioning in Patients With Schizophrenia: Beyond Negative and Cognitive Symptoms
Frontiers in Psychiatry, 2021 Introduction: Interest in the idea of recovery for certain patients with schizophrenia has been growing over the last decade. Improving symptomatology and functioning is crucial for achieving this.
María Paz García-Portilla +39 more
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Dreams, Sleep, and Psychotropic Drugs
Frontiers in Neurology, 2020 Over the past 60 years, the impact of psychotropic drugs on dream recall and content has been scarcely explored. A review of the few existing experimental results on the topic leads us to the following conclusions.
Alain Nicolas, Perrine M. Ruby
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Mechanistic modeling as an explanatory tool for clinical treatment of chronic catatonia
Frontiers in Pharmacology, 2022 Mathematical modeling of neural systems is an effective means to integrate complex information about the brain into a numerical tool that can help explain observations. However, the use of neural models to inform clinical decisions has been limited.
Patrick D. Roberts, James Conour
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Acute olanzapine toxicity in a toddler
Open Journal of Psychiatry and Allied Sciences, 2020 Olanzapine is an antipsychotic medication, which is approved for treatment of psychiatric illnesses among various age groups of psychiatric patients. Accidental consumption of olanzapine is uncommon among the paediatric age group.
Hemendra Singh +3 more
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Antipsychotic Drug Development: From Historical Evidence to Fresh Perspectives
Frontiers in Psychiatry, 2022 Schizophrenia is a complex disorder of varied etiology, manifesting symptoms that can differ between patients and change throughout an individual's lifespan.
Katrina Weston-Green +2 more
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Sudden Cardiac Death in Schizophrenia During Hospitalization: An Autopsy-Based Study
Frontiers in Psychiatry, 2022 Schizophrenia is a severe mental disorder that is often comorbid with heart dysfunction and even sudden cardiac death (SCD). Clinical studies of SCD in schizophrenia have been largely reported, while there are limited autopsy studies that directly showed
Yuanyuan Chen +9 more
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Possible inhibitory effects of terbinafine on aripiprazole metabolism: Two case reports [PDF]
Mental Health Clinician, 2021 Aripiprazole, an atypical antipsychotic, is a metabolic substrate for cytochrome P450 (CYP)3A4 and 2D6. Terbinafine, an antifungal agent used for onychomycosis, is a CYP2D6 inhibitor and could theoretically reduce the metabolism of aripiprazole. However,
Ian R. McGrane, PharmD +2 more
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Advanced Biomedical Research, 2018 Background: There have been studies on the outcome of acute intoxication with antidepressants or antipsychotics. We performed outcome prediction analysis in acute poisoning patients with antidepressants/antipsychotics with or without combination with ...
Mohadeseh Ghasemi +4 more
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