Results 11 to 20 of about 181,112 (317)

Metacognition vulnerabilities in time of crisis: Who to protect from suicidal risk?

Brain and Behavior, Volume 12, Issue 12, December 2022., 2022
Abstract Introduction During stressful events, we are all trying to cope. We may not be equal depending on our emotional, psychological, and mental states. During the COVID‐19 pandemic, we could try to avoid negative information processing and anxiogenics content to prevent unhealthy thinking processes. One of the processes we can observe regarding our
Sylvia Martin, Anna Oltra, Jonathan del Monte   +2 more
wiley   +1 more source

Self Cycloaddition of o‐Naphthoquinone Nitrosomethide to (±) Spiro{naphthalene(naphthopyranofurazan)}‐one Oxide: An Insight into its Formation

ChemPlusChem, Volume 87, Issue 12, December 2022., 2022
2‐Hydroxy‐1‐naphthaldehyde oxime was oxidized by a D−A type self cycloaddition to spiro compound. Free reaction energy is calculated at −82.0 kcal/mol indicating its predominance over the intramolecular cyclization of −37.6 kcal/mol. 8‐methoxy substituted oxime is sterically guided to 9‐methoxynaphtho[1,2‐d] instead of spiro adduct resulting to the ...
Demeter Tzeli, Ioannis E. Gerontitis, Ioannis D. Petsalakis, Petros G. Tsoungas, George Varvounis   +4 more
wiley   +1 more source

‘You are trying to teach us to think more slowly!’: Adapting Metacognitive Training for the acute care setting—A case report

Clinical Psychology &Psychotherapy, Volume 29, Issue 6, Page 1877-1885, November/December 2022., 2022
Abstract Psychological group interventions for the acute inpatient care setting are scarce. Whereas Metacognitive Training for patients with Psychosis (MCT) provides a widely accessible, easy‐to‐implement intervention for patients with mild to moderate symptoms, it is less adequate for the acute care setting with respect to length and density of ...
Rabea Fischer, Jakob Scheunemann, Alison Bohlender, Patric Duletzki, Matthias Nagel, Steffen Moritz   +5 more
wiley   +1 more source

Development in Prescriptions of Contraindicated and Potentially Harmful QT Interval–Prolonging Drugs in a Large Geriatric Inpatient Cohort From 2011 to 2021

Clinical Pharmacology &Therapeutics, Volume 113, Issue 2, Page 435-445, February 2023., 2023
Regulatory authorities put major emphasis on QT (interval)–prolonging properties of new molecular entities. Product information/Summaries of Product Characteristics (SmPCs) of multiple drugs contain warnings or contraindications regarding QT prolongation, e.g., on coadministration of QT‐prolonging drugs (QT drugs).
Melanie I. Then, Thomas Tümena, Anna Sledziewska, Karl‐Günter Gaßmann, Renke Maas, Martin F. Fromm   +5 more
wiley   +1 more source

Mechanism of Action of Atypical Antipsychotic Drugs in Mood Disorders

International Journal of Molecular Sciences, 2020
Atypical antipsychotic drugs were introduced in the early 1990s. Unlike typical antipsychotics, which are effective only against positive symptoms of schizophrenia, atypical antipsychotics are effective against negative and cognitive symptoms as well ...
D. Grinchii, E. Dremencov
semanticscholar   +1 more source

Real-World Effectiveness of Antipsychotic Treatments in a Nationwide Cohort of 29 823 Patients With Schizophrenia

JAMA psychiatry, 2017
Importance It has remained unclear whether there are clinically meaningful differences between antipsychotic treatments with regard to preventing relapse of schizophrenia, owing to the impossibility of including large unselected patient populations in ...
J. Tiihonen, E. Mittendorfer-Rutz, M. Majak, J. Mehtälä, F. Hoti, E. Jedenius, D. Enkusson, A. Leval, J. Sermon, A. Tanskanen, H. Taipale   +10 more
semanticscholar   +1 more source

Metformin add‐on vs. antipsychotic switch vs. continued antipsychotic treatment plus healthy lifestyle education in overweight or obese youth with severe mental illness: results from the IMPACT trial

World Psychiatry, 2020
Antipsychotics are used for many psychiatric conditions in youth. Although developmentally inappropriate weight gain and metabolic abnormalities, which are risk factors for premature cardiovascular mortality, are especially frequent in youth, optimal ...
C. Correll, L. Sikich, G. Reeves, Jacqueline L Johnson, Courtney P Keeton, Marina Spanos, S. Kapoor, K. Bussell, Leslie Miller, Tara Chandrasekhar, E. Sheridan, Sara Pirmohamed, Shauna P. Reinblatt, Cheryl Alderman, Abigail Scheer, I. Borner, T. Bethea, S. Edwards, R. Hamer, M. Riddle   +19 more
semanticscholar   +1 more source

Psychiatric morbidity among men using anabolic steroids

Depression and Anxiety, Volume 39, Issue 12, Page 805-812, December 2022., 2022
Abstract Objective The purpose of this study was to investigate the psychiatric morbidity among men with abuse of anabolic steroids. Methods The design is a retrospectively matched cohort study. Five hundred and fourty‐five males, who tested positive for anabolic steroids in Danish fitness centers during the period January 3, 2006 to March 1, 2018 ...
Josefine Windfeld‐Mathiasen, Thea Christoffersen, Niels August Willer Strand, Kim Dalhoff, Jon Trærup Andersen, Henrik Horwitz   +5 more
wiley   +1 more source

The affinity and selectivity of α‐adrenoceptor antagonists, antidepressants, and antipsychotics for the human α1A, α1B, and α1D‐adrenoceptors

Pharmacology Research & Perspectives, 2020
α1‐adrenoceptor antagonists are widely used for hypertension (eg, doxazosin) and benign prostatic hypertrophy (BPH, eg, tamsulosin). Some antidepressants and antipsychotics have been reported to have α1 affinity.
Richard G. W. Proudman, Andre S. Pupo, Jillian G. Baker   +2 more
doaj   +1 more source

Dose Equivalents for Antipsychotic Drugs: The DDD Method.

Schizophrenia bulletin, 2016
BACKGROUND Dose equivalents of antipsychotics are an important but difficult to define concept, because all methods have weaknesses and strongholds.
S. Leucht, M. Samara, S. Heres, John M. Davis   +3 more
semanticscholar   +1 more source