Results 21 to 30 of about 181,112 (317)
Depression and Anxiety, Volume 39, Issue 12, Page 870-880, December 2022., 2022 Abstract Background Emotional lability, defined as rapid and/or intense affect fluctuations, is associated with pediatric psychopathology. Although numerous studies have examined labile mood in clinical groups, few studies have used real‐time assessments in a well‐characterized transdiagnostic sample, and no prior study has included participants with ...
Reut Naim +5 more
wiley +1 more source
Antipsychotic Drug Development: From Historical Evidence to Fresh Perspectives
Frontiers in Psychiatry, 2022 Schizophrenia is a complex disorder of varied etiology, manifesting symptoms that can differ between patients and change throughout an individual's lifespan.
Katrina Weston-Green +2 more
doaj +1 more source
STRUCTURE OF THE D2 DOPAMINE RECEPTOR BOUND TO THE ATYPICAL ANTIPSYCHOTIC DRUG RISPERIDONE
Nature, 2018 Dopamine is a neurotransmitter that has been implicated in processes as diverse as reward, addiction, control of coordinated movement, metabolism and hormonal secretion.
Sheng Wang +5 more
semanticscholar +1 more source
Advanced Biomedical Research, 2018 Background: There have been studies on the outcome of acute intoxication with antidepressants or antipsychotics. We performed outcome prediction analysis in acute poisoning patients with antidepressants/antipsychotics with or without combination with ...
Mohadeseh Ghasemi +4 more
doaj +1 more source
Sudden Cardiac Death in Schizophrenia During Hospitalization: An Autopsy-Based Study
Frontiers in Psychiatry, 2022 Schizophrenia is a severe mental disorder that is often comorbid with heart dysfunction and even sudden cardiac death (SCD). Clinical studies of SCD in schizophrenia have been largely reported, while there are limited autopsy studies that directly showed
Yuanyuan Chen +9 more
doaj +1 more source
Management of common adverse effects of antipsychotic medications
World Psychiatry, 2018 The benefits of antipsychotic medications are sometimes obscured by their adverse effects. These effects range from relatively minor tolerability issues (e.g., mild sedation or dry mouth) to very unpleasant (e.g., constipation, akathisia, sexual ...
T. Stroup, Neil Gray
semanticscholar +1 more source
JAMA psychiatry, 2019 Importance The effectiveness of antipsychotic polypharmacy in schizophrenia relapse prevention is controversial, and use of multiple agents is generally believed to impair physical well-being.
J. Tiihonen +5 more
semanticscholar +1 more source
What is the risk‐benefit ratio of long‐term antipsychotic treatment in people with schizophrenia?
World Psychiatry, 2018 The long‐term benefit‐to‐risk ratio of sustained antipsychotic treatment for schizophrenia has recently been questioned. In this paper, we critically examine the literature on the long‐term efficacy and effectiveness of this treatment. We also review the
C. Correll, J. Rubio, J. Kane
semanticscholar +1 more source
Pharmacology Research & Perspectives, 2022 α2‐Adrenoceptors, subdivided into α2A, α2B, and α2C subtypes and expressed in heart, blood vessels, kidney, platelets and brain, are important for blood pressure, sedation, analgesia, and platelet aggregation.
Richard G.W. Proudman +2 more
doaj +1 more source
Endocrinology, Diabetes &Metabolism, Volume 6, Issue 1, January 2023., 2023 Insulin resistance (IR) in adolescents with obesity is associated with a sex‐dependent metabolic “signature” comprising the branched‐chain amino acids (BCAAs), glutamate/glutamine, C3/C5 acylcarnitines, and uric acid. Here, we compared the levels of branched‐chain α‐keto acids (BCKAs) and glutamate/glutamine, which are byproducts of BCAA catabolism, as
Pinar Gumus Balikcioglu +8 more
wiley +1 more source