Results 121 to 130 of about 3,362,668 (327)

Association between glucagon‐like peptide‐1 receptor agonists and risk of dementia in older adults with type 2 diabetes: A target trial emulation

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Aim Type 2 diabetes (T2D) is associated with increased dementia risk, but comparative data across newer glucose‐lowering therapies remain limited. We examined whether the initiation of GLP‐1 receptor agonists (GLP‐1 RAs) was associated with incident dementia compared with DPP4 inhibitors (DPP4is) and SGLT2 inhibitors (SGLT2is) in older adults ...
Ting Zhou   +9 more
wiley   +1 more source

Mental health changes after 4 months of weight loss treatment with the glucagon‐like peptide‐1 analogue liraglutide 3.0 mg

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Objective This observational study examined changes in mental health and wellbeing after 4‐months liraglutide 3.0 mg treatment in patients with obesity and explored associations with weight loss. Methods We included 98 patients with obesity treated with liraglutide 3.0 mg.
Susanne Kuckuck   +7 more
wiley   +1 more source

Chromeno[3,4-c]pyridin-5-ones:  Selective Human Dopamine D4 Receptor Antagonists as Potential Antipsychotic Agents

open access: green, 1997
Paul C. Unangst   +7 more
openalex   +1 more source

Parkinson's Disease and Salivary Issues: A Survey

open access: yesGerodontology, EarlyView.
ABSTRACT Background Salivary dysfunction, including xerostomia and drooling, is common in Parkinson's disease and further impairs oral health and quality of life, which are already compromised in this population. Their effective management demands deeper insight into the complexity of salivary dysfunction.
Beau D. M. van Dijk   +3 more
wiley   +1 more source

Polypharmacy in HIV: Rethinking what counts and why it matters

open access: yesHIV Medicine, EarlyView.
Abstract Polypharmacy, the concurrent use of multiple medications, presents a growing challenge in HIV care as people living with HIV age and experience earlier onset of age‐related co‐morbidities. However, how polypharmacy is defined and assessed in HIV research remains inconsistent.
Luxsena Sukumaran   +6 more
wiley   +1 more source

Correction: Clozapine, a Novel Antipsychotic Agent [PDF]

open access: bronze, 1994
Olga Delgado Sánchez   +1 more
openalex   +1 more source

Medical Knowledge Integration Into Reinforcement Learning Algorithms for Dynamic Treatment Regimes

open access: yesInternational Statistical Review, EarlyView.
Summary The goal of precision medicine is to provide individualised treatment at each stage of chronic diseases, a concept formalised by dynamic treatment regimes (DTR). These regimes adapt treatment strategies based on decision rules learned from clinical data to enhance therapeutic effectiveness.
Sophia Yazzourh   +3 more
wiley   +1 more source

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