Results 131 to 140 of about 96,867 (352)
Movement Disorders Clinical Practice, EarlyView.Abstract Background The treatment of levodopa‐induced dyskinesia in Parkinson's disease (PD) is a largely unmet need. Objectives Mesdopetam is a novel small molecule dopamine D3 receptor antagonist aimed for the treatment of levodopa‐induced dyskinesia.
Angelo Antonini +6 more
wiley +1 more source
Development and implementation of an aspiration pneumonia cause investigation algorithm
The Clinical Respiratory Journal, Volume 17, Issue 1, Page 20-28, January 2023., 2023 Aspiration pneumonia remains an underdiagnosed and unestablished diagnosis. We propose the use of an algorithm (developed based on the JRS guidelines) to enable adequate management of older adults with pneumonia. When implemented in an acute setting, the algorithm enhanced the diagnosis of causative conditions, swallow screening, and preventative ...
Yuki Yoshimatsu +8 more
wiley +1 more source
Farmeconomia: Health Economics and Therapeutic Pathways, 2011 Objective: to comparatively investigate – by means of computer simulations – the economic cost and clinical outcomes of five atypical oral antipsychotic agents (ziprasidone, olanzapina, risperidone, paliperidone and aripiprazolo).
Andrea Fagiolini +4 more
doaj +1 more source
Understanding how foods and enteral feedings influence the gut microbiome
Nutrition in Clinical Practice, EarlyView.Abstract The gut microbiome supports both gut and overall health. Diet is known to be one of the driving factors that influences the gut microbiome. The foods we eat, the dietary and nondietary components they contain, various food consumption patterns, and the ratio of nutrients consumed have been shown to impact gut microbiome composition and ...
Gail A. M. Cresci
wiley +1 more source
ANTIPSYCHOTIC AGENTS IN ANXIETY DISORDERS: AN UMBRELLA REVIEW [PDF]
Int J NeuropsychopharmacolRafael C. Freire +8 more
europepmc +2 more sources
Cooperative Heterogeneous Deep Reinforcement Learning [PDF]
arXiv, 2020 Numerous deep reinforcement learning agents have been proposed, and each of them has its strengths and flaws. In this work, we present a Cooperative Heterogeneous Deep Reinforcement Learning (CHDRL) framework that can learn a policy by integrating the advantages of heterogeneous agents.
arxiv
Osteocyte-Driven Downregulation of Snail Restrains Effects of Drd2 Inhibitors on Mammary Tumor Cells [PDF]
, 2018 While bone is a frequent target of breast cancer-associated metastasis, little is known about the effects of tumor-bone interactions on the efficacy of tumor-suppressing agents.
Chen, Andy +8 more
core +1 more source
European Journal of Neurology, Volume 30, Issue 1, Page 224-234, January 2023., 2023 How long is the response to galcanezumab in real life? Findings: In this longitudinal cohort study, considering 1‐year treatment, the included 191 patients presented a 50% response rate (RR) to galcanezumab for a median of 9 cumulative months. Favorable predictive factors were monthly migraine days ≥50% RR in the first month of therapy, and effective ...
Fabrizio Vernieri +32 more
wiley +1 more source
Human Genome data analyzed by an evolutionary method suggests a decrease in cerebral protein-synthesis rate as cause of schizophrenia and an increase as antipsychotic mechanism [PDF]
arXiv, 2001 The Human Genome Project (HGP) provides researchers with the data of nearly all human genes and the challenge to use this information for elucidating the etiology of common disorders. A secondary Darwinian method was applied to HGP and other research data to approximate and possibly unravel the etiology of schizophrenia.
arxiv
Dosing strategies for switching from oral risperidone to paliperidone palmitate: Effects on clinical outcomes. [PDF]
, 2017 IntroductionThere are currently no guidelines for switching patients from oral risperidone to paliperidone palmitate (Invega Sustenna®). Furthermore, the paliperidone long-acting injectable (LAI) package insert does not recommend bridging with oral ...
Hsia, Stephanie L +4 more
core +2 more sources