Results 121 to 130 of about 132,795 (279)

Safety of Antihypertensive Medication for the Management of Non‐Severe Gestational Hypertension Among Pregnant Individuals in Botswana—Emulating a Series of Target Trials

Paediatric and Perinatal Epidemiology, EarlyView.
ABSTRACT Background Data on antihypertensive medication for non‐severe gestational hypertension may suffer from immortal time and selection bias. Emulating target trials can prevent these biases by aligning follow‐up with treatment initiation. Objectives We estimated the safety of antihypertensive medication initiation for the treatment of non‐severe ...
Julia D. DiTosto, Rebecca Zash, Denise L. Jacobson, Katherine Johnson, Modiegi Diseko, Gloria Mayondi, Judith Mabuta, Mompati Mmalane, Joseph Makhema, Sunni L. Mumford, Shahin Lockman, Roger Shapiro, Ellen C. Caniglia   +12 more
wiley   +1 more source

The role of acquired host immunity in periodontal diseases

Periodontology 2000, EarlyView.
Abstract The aim of this narrative review is to relate the contribution of European researchers to the complex topic of the host immune system in periodontal disease, focusing on acquired immunity. Other chapters in this volume will address the genetics and autoantibody responses and other forms of immunity to periodontal disease.
Denis F. Kinane, David F. Lappin, Shauna Culshaw   +2 more
wiley   +1 more source

Antibiotic‐mediated immune modulation in periodontitis

Periodontology 2000, EarlyView.
Abstract Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth. Although initiated by dysbiotic microbial communities, its progression is largely driven by the host's uncontrolled inflammatory response. While antibiotics have conventionally been employed in periodontitis therapy for their antimicrobial ...
Lina J. Suárez, R. M. Arce, Camila Pinheiro Furquim, Cristiane Gonçalves, Alpdogan Kantarci, Magda Feres, Nidia C. Castro dos Santos   +6 more
wiley   +1 more source

Antiretroviral Drug Repositioning for Glioblastoma

Cancers
Outcomes for glioblastoma (GBM) remain poor despite standard-of-care treatments including surgical resection, radiation, and chemotherapy. Intratumoral heterogeneity contributes to treatment resistance and poor prognosis, thus demanding novel therapeutic approaches.
Sarah R. Rivas, Mynor J. Mendez Valdez, Jay S. Chandar, Jelisah F. Desgraves, Victor M. Lu, Leo Ampie, Eric B. Singh, Deepa Seetharam, Christian K. Ramsoomair, Anna Hudson, Shreya M. Ingle, Vaidya Govindarajan, Tara T. Doucet-O’Hare, Catherine DeMarino, John D. Heiss, Avindra Nath, Ashish H. Shah   +16 more
openaire   +2 more sources

Improving Treatment Outcome for Children with HIV [PDF]

, 2011
Calmy, Alexandra L, Ford, Nathan
core   +2 more sources

Aid to Fight AIDS: An Empirical Analysis of HIV‐Specific Development Aid Effectiveness

Scottish Journal of Political Economy, EarlyView.
ABSTRACT Using an excludable instrument for HIV‐specific aid, we investigate its effectiveness on HIV outcomes viz., prevalence and death rates. We theorize that HIV‐specific aid fills the funding gap that prevents governments from committing adequate resources to effectively address the epidemic.
Derek Nolan, Krishna Chaitanya Vadlamannati   +1 more
wiley   +1 more source

How Much Does It Cost to Provide Antiretroviral Therapy for HIV/AIDS in Africa? [PDF]

, 2010
Background: Many African countries are rapidly expanding HIV/AIDS treatment programs. Empirical information on the cost of delivering antiretroviral therapy (ART) for HIV/AIDS is needed for program planning and budgeting.
Long, Lawrence, Rosen, Sydney
core   +1 more source

HHV‐8/KSHV in Solid Organ Transplantation: Current Gaps of Knowledge and Future Directions

Transplant Infectious Disease, EarlyView.
Risk mitigation strategies, including donors/recipients screening, DNAemia monitoring in recipients at risk, CNI‐to‐mTOR inhibitors switch, antivirals, and rituximab for KICS, may mitigate the impact of HHV‐8/KSHV infection in SOT. This review provides an update on KICS, identifies research gaps, and summarizes advances in screening and management ...
Alessandra Mularoni, Andrea Cona, Malgorzata Mikulska, Francesca Pecoraro, Carlotta Piazza, Elda De Vita, Giada Pietrosi, Matteo Bulati, Tiziana Lazzarotto, Mario Luppi   +9 more
wiley   +1 more source

In vitro Study of Elution Characteristics of Antiviral Drugs Immersed in Bone Cement

Туберкулез и болезни лёгких
The objective: to assess elution characteristics of certain antiviral drugs immersed in bone cement samples and placed in a liquid medium to determine the fundamental possibility of using such systems.Subjects and Methods.
E. O. Peretsmanas, A. A. Artyukhov, I. A. Gerasimov, V. S. Zubikov, T. E. Tyulkova, Ya. A. Rukin   +5 more
doaj   +1 more source

The Ghana retention on ART study (ROARS): keeping HIV-positive patients on antiretroviral therapy [PDF]

, 2014
This study was implemented by Boston University in collaboration with the Kwame Nkrumah University of Science and Technology with support from the President’s Emergency Plan for AIDS Relief (PEPFAR) through the U.S.
Abacan, Allyssa, Adu‐Sarkodie, Yaw, Agyarko‐Poku, Thomas, Beard, Jennifer, Falconer, Ariel, Kissiwah Asafo, Mabel, Longobardi, Dana, Messersmith, Lisa, Myint Zu Kyaw, Mya, Sabin, Lora   +9 more
core