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Recent advances in antiretroviral drugs
Expert Opinion on Pharmacotherapy, 2010Acquired immunodeficiency syndrome (AIDS) is one of the leading causes of death worldwide. Although the combination therapies of highly active antiretroviral therapy (HAART) have significantly contributed to virological suppression, improved immune function and quality of life, issues such as tolerability, drug-drug interactions and cross-resistance ...
Raktim Kumar, Ghosh +2 more
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Drug interactions among the antiretrovirals
Current Infectious Disease Reports, 2004There are 20 antiretroviral agents approved by the US Food and Drug Administration (FDA), four of which were approved in 2003. With 20 antiretrovirals FDA-approved, interactions occur when the medications alter the toxicity profile or efficacy of the other medication.
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Peripheral neuropathy and antiretroviral drugs
Journal of the Peripheral Nervous System, 2001Abstract Patients treated with nucleoside analogue reverse transcriptase inhibitors (NRTIs) develop a varying degree of myopathy or neuropathy after long‐term therapy. Zidovudine (AZT) causes myopathy; zalcitabine (ddC), didanosine (ddI) and lamuvidine (3TC) cause neuropathy; stavudine (d4T) and fialuridine (FIAU) cause neuropathy or myopathy and ...
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[Resistance to antiretroviral drugs].
Recenti progressi in medicina, 2001Since the HIV eradication is an utopian goal the only hope we have is the appropriate follow up of the disease by maintaining the RNA viral load under control and the level of CD4+ sufficient for a minimum of immunocompetence guarantee. The international guideline for the management of HIV infected patients, annually updated, recently confirmed the ...
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Cancer epigenetics in clinical practice
Ca-A Cancer Journal for Clinicians, 2023Veronica Davalos, Manel Esteller
exaly