Results 41 to 50 of about 132,795 (279)

CELLULAR RESISTANCE TO THE ANTIRETROVIRAL DRUGS

Microbiologia Medica, 2004
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G. Antonelli
doaj   +1 more source

Hepatotoxicity of Contemporary Antiretroviral Drugs: A Review and Evaluation of Published Clinical Data

Cells, 2021
Contemporary antiretroviral agents afford enhanced potency and safety for patients living with HIV. Newer antiretroviral drugs are often better tolerated than those initially approved in the early stages of the HIV epidemic.
Ashley O. Otto, Christina G. Rivera, John D. Zeuli, Zelalem Temesgen   +3 more
doaj   +1 more source

Personalizing HIV therapy, mission impossible? [PDF]

, 2012
Sustained HIV suppression depends on a number of factors including therapy adherence, management of side effects, viral resistance and individual characteristics of patients and therapeutic settings.
Hentig, Nils von
core   +1 more source

Immediate Antiretroviral Therapy Decreases Mortality Among Patients With High CD4 Counts in China: A Nationwide, Retrospective Cohort Study. [PDF]

, 2017
BackgroundClinical trials have demonstrated that immediate initiation of antiretroviral therapy (ART) reduces AIDS-related morbidity and mortality. We tested the hypothesis that initiating ART ≤30 days after human immunodeficiency virus (HIV) diagnosis ...
Brookmeyer, Ron, Detels, Roger, Dou, Zhihui, Li, Aihua, Ma, Ye, McGoogan, Jennifer M, Montaner, Julio SG, Qin, Qianqian, Shi, Cynthia X, Wu, Zunyou, Zhao, Yan   +10 more
core   +1 more source

Nanoparticle delivery system, highly active antiretroviral therapy, and testicular morphology: The role of stereology

Pharmacology Research & Perspectives, 2021
The conjugation of nanoparticles (NPs) with antiretroviral drugs is a drug delivery approach with great potential for managing HIV infections. Despite their promise, recent studies have highlighted the toxic effects of nanoparticles on testicular tissue ...
Edwin Coleridge S. Naidu, Samuel Oluwaseun Olojede, Sodiq Kolawole Lawal, Carmen Olivia Rennie, Onyemaechi Okpara Azu   +4 more
doaj   +1 more source

Current antiretroviral therapy: A review

Терапевтический архив, 2023
The article presents an overview of clinical recommendations for currant antiretroviral therapy. Currently, the current preferred first-line antiretroviral therapy regimens are combinations of 2 or 3 antiretroviral drugs (ARVs) in one tablet with a ...
Alexey V. Kravchenko, Viktor V. Maleyev
doaj   +1 more source

Human Vault Nanoparticle Targeted Delivery of Antiretroviral Drugs to Inhibit Human Immunodeficiency Virus Type 1 Infection. [PDF]

, 2019
"Vaults" are ubiquitously expressed endogenous ribonucleoprotein nanoparticles with potential utility for targeted drug delivery. Here, we show that recombinant human vault nanoparticles are readily engulfed by certain key human peripheral blood ...
Anton, Peter A, Deming, Timothy, Elliott, Julie, Fulcher, Jennifer A, Ibarrondo, F Javier, Kickhoefer, Valerie A, Maynard, Heather D, Mrazek, Jan, Rome, Leonard H, Tamshen, Kyle, Wollenberg, Alexander L, Yang, Otto O   +11 more
core  

Factors predictive of successful retention in care among HIV-infected men in a universal test-and-treat setting in Uganda and Kenya: A mixed methods analysis. [PDF]

, 2019
BackgroundPrevious research indicates clinical outcomes among HIV-infected men in sub-Saharan Africa are sub-optimal. The SEARCH test and treat trial (NCT01864603) intervention included antiretroviral care delivery designed to address known barriers to ...
Atukunda, Mucunguzi, Ayieko, James, Brown, Lillian B, Bukusi, Elizabeth A, Camlin, Carol S, Charlebois, Edwin D, Clark, Tamara, Cohen, Craig R, Getahun, Monica, Havlir, Diane V, Kamya, Moses R, Kwarisiima, Dalsone, Olilo, Winter, Owaraganise, Asiphas, Petersen, Maya L   +14 more
core   +2 more sources

A critical review, and up-to-date research progress on the occurrence, and removal of antiretroviral drugs in water

Desalination and Water Treatment
In the last decade, research on identification of antiretroviral drugs in water has intensified, especially in the developing countries. Concentrations reaching 33 µg/L for efavirenz have been reported in wastewater effluent which is released into the ...
Lawrence M. Madikizela
doaj   +1 more source

Development of Buffalo Hump in the course of antiretroviral therapy including raltegravir and unboosted atazanavir: a case report and review of the literature

Journal of Medical Case Reports, 2011
Introduction The availability of raltegravir plus atazanavir provides an alternative antiretroviral strategy that may be equally efficacious and less toxic than those currently recommended in HIV treatment guidelines.
Mastroianni Claudio M, Rizza Cecilia, Marchetti Francesco, d'Ettorre Gabriella, Ceccarelli Giancarlo, Carlesimo Bruno, Vullo Vincenzo   +6 more
doaj   +1 more source