Results 61 to 70 of about 141,326 (319)

Identification of drug resistance mutations in HIV from constraints on natural evolution [PDF]

open access: yesPhys. Rev. E 93, 022412 (2016), 2015
Human immunodeficiency virus (HIV) evolves with extraordinary rapidity. However, its evolution is constrained by interactions between mutations in its fitness landscape. Here we show that an Ising model describing these interactions, inferred from sequence data obtained prior to the use of antiretroviral drugs, can be used to identify clinically ...
arxiv   +1 more source

Management of Reduced Bone Mineral Density in HIV: Pharmacological Challenges and the Role of Exercise

open access: yesFrontiers in Physiology, 2018
Low bone mineral density is becoming more common among people living with HIV following the use of current antiretroviral therapy drugs such as tenofovir.
Enock M. Chisati   +2 more
doaj   +1 more source

When to Start Antiretroviral Therapy [PDF]

open access: yesCurrent HIV/AIDS Reports, 2010
The question of when to start combination antiretroviral therapy for treatment-naïve patients has always been controversial. This is particularly true in the current era, with major guidelines recommending very different treatment strategies. Despite a lack of clarity regarding the optimal time to begin therapy, there has been a recent shift toward ...
Jain, Vivek, Deeks, Steven G.
openaire   +4 more sources

A review of Mpox: Biological characteristics, epidemiology, clinical features, diagnosis, treatment, and prevention strategies

open access: yesExploration, EarlyView.
The monkeypox virus (MPXV) has spread to many countries and caused thousands of infections all over the world. This review comprehensively introduces the biology, epidemiological characteristics of MPXV, and clinical manifestations of Mpox. The approaches for diagnosis, treatment, and prevention are also introduced, aiming to improve the general ...
Lin Jiang   +15 more
wiley   +1 more source

Use of antiretroviral therapy in households and risk of HIV acquisition in rural KwaZulu-Natal, South Africa, 2004–12: a prospective cohort study

open access: yesThe Lancet Global Health, 2014
Background: Studies of HIV-serodiscordant couples in stable sexual relationships have provided convincing evidence that antiretroviral therapy can prevent the transmission of HIV.
Alain Vandormael, MS   +3 more
doaj   +1 more source

Incidence of paradoxical tuberculosis-associated immune reconstitution inflammatory syndrome and impact on patient outcome. [PDF]

open access: yesPLoS ONE, 2013
We used data from a randomized trial of HIV-tuberculosis co-infected patients in Mozambique to determine the incidence and predictors of paradoxical tuberculosis-associated immune reconstitution inflammatory syndrome (IRIS) occurring within 12 weeks of ...
Maryline Bonnet   +8 more
doaj   +1 more source

Care, and the less of it: Haunted gestures and the affective economy of pharmaceutical HIV prevention

open access: yesFeminist Anthropology, EarlyView.
Abstract Pre‐exposure prophylaxis (PrEP) is an antiretroviral drug that effectively prevents an HIV infection, which German statutory health insurance has covered since 2019. The drug's use in Germany has (re)surfaced ambivalent emotions: hopes for an HIV/AIDS‐free future and sexual liberation rub against enduring worries and moralizations of ...
Max Schnepf
wiley   +1 more source

Assessment of antiretroviral therapy knowledge and willingness of persons with HIV to support its uptake in Uganda

open access: yesPatient Preference and Adherence, 2011
Richard Batamwita1, David M Moore2, Rachel King3, Edward Mills4, Anne L Stangl5 1Mildmay Centre, Kampala, Uganda; 2British Columbia Centre for Excellence in HIV/AIDS, Vancouver, Canada; 3Karolinska Institute, Stockholm, Sweden; 4University of Ottawa ...
Batamwita R   +4 more
doaj  

Hematological parameters abnormalities and associated factors in HIV-positive adults before and after highly active antiretroviral treatment in Goba Referral Hospital, southeast Ethiopia: A cross-sectional study

open access: yesSAGE Open Medicine, 2021
Objectives: Hematological abnormalities of the major blood cell lines are frequently reported in patients with HIV-1 infection, in patients without antiretroviral therapy, and during the advanced stages of the disease.
Negesso Duguma   +3 more
doaj   +1 more source

Fitting analysis provides further evidence for eradication of hiv/aids infection under combined liposome drug delivery treatment [PDF]

open access: yesDrug Delivery Systems and Sciences (UK). 2003, volume 3, No 2, pp. 49-51, 2007
It is now evident that the commonly accepted strategy for treatment of HIV/AIDS by highly active antiretroviral therapy (HAART) will not lead to eradication of HIV in a reasonable time. This is straightforward from the typical exponential viral load decay upon treatment revealing initial considerable but incomplete reduction of plasma HIV RNA with ...
arxiv  

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