Results 61 to 70 of about 141,326 (319)
Identification of drug resistance mutations in HIV from constraints on natural evolution [PDF]
Human immunodeficiency virus (HIV) evolves with extraordinary rapidity. However, its evolution is constrained by interactions between mutations in its fitness landscape. Here we show that an Ising model describing these interactions, inferred from sequence data obtained prior to the use of antiretroviral drugs, can be used to identify clinically ...
arxiv +1 more source
Low bone mineral density is becoming more common among people living with HIV following the use of current antiretroviral therapy drugs such as tenofovir.
Enock M. Chisati+2 more
doaj +1 more source
When to Start Antiretroviral Therapy [PDF]
The question of when to start combination antiretroviral therapy for treatment-naïve patients has always been controversial. This is particularly true in the current era, with major guidelines recommending very different treatment strategies. Despite a lack of clarity regarding the optimal time to begin therapy, there has been a recent shift toward ...
Jain, Vivek, Deeks, Steven G.
openaire +4 more sources
The monkeypox virus (MPXV) has spread to many countries and caused thousands of infections all over the world. This review comprehensively introduces the biology, epidemiological characteristics of MPXV, and clinical manifestations of Mpox. The approaches for diagnosis, treatment, and prevention are also introduced, aiming to improve the general ...
Lin Jiang+15 more
wiley +1 more source
Background: Studies of HIV-serodiscordant couples in stable sexual relationships have provided convincing evidence that antiretroviral therapy can prevent the transmission of HIV.
Alain Vandormael, MS+3 more
doaj +1 more source
Incidence of paradoxical tuberculosis-associated immune reconstitution inflammatory syndrome and impact on patient outcome. [PDF]
We used data from a randomized trial of HIV-tuberculosis co-infected patients in Mozambique to determine the incidence and predictors of paradoxical tuberculosis-associated immune reconstitution inflammatory syndrome (IRIS) occurring within 12 weeks of ...
Maryline Bonnet+8 more
doaj +1 more source
Abstract Pre‐exposure prophylaxis (PrEP) is an antiretroviral drug that effectively prevents an HIV infection, which German statutory health insurance has covered since 2019. The drug's use in Germany has (re)surfaced ambivalent emotions: hopes for an HIV/AIDS‐free future and sexual liberation rub against enduring worries and moralizations of ...
Max Schnepf
wiley +1 more source
Richard Batamwita1, David M Moore2, Rachel King3, Edward Mills4, Anne L Stangl5 1Mildmay Centre, Kampala, Uganda; 2British Columbia Centre for Excellence in HIV/AIDS, Vancouver, Canada; 3Karolinska Institute, Stockholm, Sweden; 4University of Ottawa ...
Batamwita R+4 more
doaj
Objectives: Hematological abnormalities of the major blood cell lines are frequently reported in patients with HIV-1 infection, in patients without antiretroviral therapy, and during the advanced stages of the disease.
Negesso Duguma+3 more
doaj +1 more source
Fitting analysis provides further evidence for eradication of hiv/aids infection under combined liposome drug delivery treatment [PDF]
It is now evident that the commonly accepted strategy for treatment of HIV/AIDS by highly active antiretroviral therapy (HAART) will not lead to eradication of HIV in a reasonable time. This is straightforward from the typical exponential viral load decay upon treatment revealing initial considerable but incomplete reduction of plasma HIV RNA with ...
arxiv