Results 71 to 80 of about 139,558 (270)

Social and clinical attributes of patients who restart antiretroviral therapy in central and Copperbelt provinces, Zambia: a retrospective longitudinal study

BMC Public Health, 2016
Background About 30 % of the patients initiated on antiretroviral therapy in Zambia default treatment. Some of these patients later restart treatment; however, the characteristics of these patients have not been well described and documented.
Chama Mulubwa, Oliver Mweemba, Patrick Katayamoyo, Hikabasa Halwindi   +3 more
doaj   +1 more source

Distinct characteristics and social determinants in adult T‐cell leukaemia/lymphoma patients at a tertiary cancer centre in Canada

British Journal of Haematology, EarlyView.
Adult T‐cell leukaemia/lymphoma (ATLL) is a rare, aggressive cancer linked to HTLV‐1, with poor outcomes. We analysed 79 ATLL patients (1993–2023) at our institution. The median age at diagnosis was 47 years, with 72% of patients of Caribbean origin. Median progression‐free and overall survival were 10.2 and 16.2 months respectively. CNS involvement at
Tomohiro Aoki, Mary Salib, Adam Suleman, Noorhan Ghanem, Michael Hong, Agustina Boriano, Abi Vijenthira, Anca Prica, John Kuruvilla, Vishal Kukreti, Michael Crump, Robert Kridel   +11 more
wiley   +1 more source

Organoid Models to Study Human Infectious Diseases

Cell Proliferation, EarlyView.
Our manuscript reviews the role of organoids as models for studying human infectious diseases, highlighting their irreplaceable contributions to drug testing and vaccine development for significant infectious diseases including HIV, ZIKV, SARS‐CoV‐2 and MPXV.
Sijing Zhu, Dan Chen, Xinzhi Yang, Liuliu Yang, Yuling Han   +4 more
wiley   +1 more source

Comparative Analysis of the Properties of Acid-Base Indicator of Rose (Rosa setigera), Allamanda (Allamanda cathartica), and Hibiscus (Hibiscus rosa-sinensis) Flowers

Biochemistry Research International, 2015
The need to develop effective alternative for synthetic indicators is the demand of present-day chemistry. The acid-base indicator properties of Rose (Rosa setigera), Allamanda (Allamanda cathartica), and Hibiscus (Hibiscus rosa-sinensis) flowers were ...
Stanley I. R. Okoduwa, Lovina O. Mbora, Matthew E. Adu, Ameh A. Adeyi   +3 more
doaj   +1 more source

Impact of antiretroviral therapy on renal function among HIV-infected Tanzanian adults: a retrospective cohort study.

PLoS ONE, 2014
BackgroundData regarding the outcomes of HIV-infected adults with baseline renal dysfunction who start antiretroviral therapy are conflicting.MethodsWe followed up a previously-published cohort of HIV-infected adult outpatients in northwest Tanzania who ...
Bonaventura C T Mpondo, Samuel E Kalluvya, Robert N Peck, Rodrick Kabangila, Benson R Kidenya, Lucheri Ephraim, Daniel W Fitzgerald, Jennifer A Downs   +7 more
doaj   +1 more source

Adherence to Antiretroviral Therapy Among HIV-Positive Pregnant Women on followup at Mizan Tepi University Teaching and Tepi General Hospitals, Southwest Ethiopia

Journal of Primary Care & Community Health, 2020
Background: The introduction of highly active antiretroviral therapy has not only improved longevity in human immunodeficiency virus (HIV)–infected individuals but in addition has had a significant impact on the rate of mother-to-child transmission of ...
Temesgen Aferu, Gatluak Doang, Ameha Zewudie, Tadesse Nigussie   +3 more
doaj   +1 more source

The Complex Nature of Adherence in the Management of HIV/AIDS as a Chronic Medical Condition

Diseases, 2013
The introduction of antiretroviral therapy (ART) in the management of HIV infection has resulted in a significant reduction in the morbidity and mortality associated with the disease.
Adegoke O. Adefolalu, Zerish Z. Nkosi
doaj   +1 more source

Torque teno virus as a marker of immune status in immunocompromised patients: A systematic review

European Journal of Clinical Investigation, EarlyView.
Abstract Background Torque teno virus (TTV) is not known to cause disease in humans; however, chronic inflammatory conditions and immunosuppression states can favour TTV replication. This study aimed to verify the effectiveness of TTV as an immune biomarker.
Janaina B. Medina, Fábio França Vieira e Silva, Rafael Antônio Velôso Caixeta, Bruna de Oliveira Rech, Alba Perez‐Jardón, María Elena Padín‐Iruegas, Mario Pérez‐Sayáns, Paulo Henrique Braz‐Silva, Karem L. Ortega   +8 more
wiley   +1 more source

Incidence rate of modifying or discontinuing first combined antiretroviral therapy regimen due to toxicity during the first year of treatment stratified by age

Brazilian Journal of Infectious Diseases, 2014
Toxicity is the most frequently reported reason for modifying or discontinuing the first combined antiretroviral therapy regimens, and it can cause significant morbidity, poor quality of life and also can be an important barrier to adherence, ultimately ...
Thiago Silva Torres, Sandra Wagner Cardoso, Luciane S. Velasque, Valdilea G. Veloso, Beatriz Grinsztejn   +4 more
doaj  

Cause-Specific Mortality in HIV-Positive Patients Who Survived Ten Years after Starting Antiretroviral Therapy.

PLoS ONE, 2016
ObjectivesTo estimate mortality rates and prognostic factors in HIV-positive patients who started combination antiretroviral therapy between 1996-1999 and survived for more than ten years.MethodsWe used data from 18 European and North American HIV cohort
Adam Trickey, Margaret T May, Janne Vehreschild, Niels Obel, Michael John Gill, Heidi Crane, Christoph Boesecke, Hasina Samji, Sophie Grabar, Charles Cazanave, Matthias Cavassini, Leah Shepherd, Antonella d'Arminio Monforte, Colette Smit, Michael Saag, Fiona Lampe, Vicky Hernando, Marta Montero, Robert Zangerle, Amy C Justice, Timothy Sterling, Jose Miro, Suzanne Ingle, Jonathan A C Sterne, Antiretroviral Therapy Cohort Collaboration (ART-CC)   +24 more
doaj   +1 more source