Weaknesses out of strength: PNA against the penicillin-binding proteins. [PDF]
Wdowiak M.
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ABSTRACT Background Circular RNA (hsa_circ_0070354), also known as circPTPN13, was demonstrated in our previous study that it can be used as a biomarker for diagnosing non‐small cell lung cancer (NSCLC). However, the mechanism of its role in the occurrence and development of NSCLC has not been investigated.
Yuejiao Huang +7 more
wiley +1 more source
Systemic distribution of tricyclo-DNA antisense oligonucleotide following intratracheal instillation in the mouse. [PDF]
Laurent J +6 more
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Figure 1 visually summarizes the core biological functions and therapeutic potential of the HGF/c‐Met signaling axis. Abstract Hepatocyte growth factor (HGF) is a multifunctional cytokine that activates the tyrosine kinase activity of its specific receptor, c‐Met (mesenchymal–epithelial transition factor).
Hongqin Sun +7 more
wiley +1 more source
Enhanced liver-targeted delivery with ribofuranose-based GalNAc conjugates. [PDF]
Pradeep SP, Ruchi R, Bahal R.
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Progress of Immunotherapies in Parkinson's Disease
Parkinson's disease (PD) is caused by an immune disorder triggered by α‐synuclein, leading to a persistent neuroinflammatory cycle that drives the disease from non‐motor symptoms to the motor stage. Second, it presents active and passive immunotherapy strategies targeting α‐synuclein and their potential in slowing down the disease progression.
Yong Peng +10 more
wiley +1 more source
Targeting Non-Coding RNAs as a Potential Therapeutic and Delivery Strategy Against Neurodegenerative Diseases. [PDF]
Bougea A.
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Gene Targeted Therapies for Neurodegenerative Disorders: Strategies and Implications in ALS and SMA. [PDF]
Yesbek Kaymaz A +3 more
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MicroRNAs in cancer: biogenesis, biomarkers and therapeutic strategies. [PDF]
Rawat N, Babu N, Hussain A, Panwar AS.
europepmc +1 more source
RNA therapies are delivering as therapies for neuromuscular dystrophy patients: Editorial for the special issue on RNA therapies in Journal of Neuromuscular Diseases. [PDF]
Aartsma-Rus A, Takeda S.
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