Results 171 to 180 of about 263,156 (310)

Tailored antisense oligonucleotides designed to correct aberrant splicing reveal actionable groups of mutations for rare genetic disorders

Experimental and Molecular Medicine
Effective translation of rare disease diagnosis knowledge into therapeutic applications is achievable within a reasonable timeframe; where mutations are amenable to current antisense oligonucleotide technology.
Htoo A. Wai, Eliska Svobodova, Natalia Romero Herrera, Andrew G. L. Douglas, John W. Holloway, Francisco E. Baralle, Marco Baralle, Diana Baralle   +7 more
doaj   +1 more source

Synergistic inhibition of human cancer cell growth by cytotoxic drugs and mixed backbone antisense oligonucleotide targeting protein kinase A [PDF]

, 1997
Giampaolo Tortora, Rosa Caputo, Vincenzo Damiano, Roberto Bianco, Stefano Pepe, A R Bianco, Zhiwei Jiang, Sudhir Agrawal, Fortunato Ciardiello   +8 more
openalex   +1 more source

Antisense oligonucleotide inhibition of acetylcholinesterase gene expression induces progenitor cell expansion and suppresses hematopoietic apoptosis ex vivo.

, 1994
Hermona Soreq, Deborah Patinkin, Efrat Lev-Lehman, Mirta Grifman, Dalia Ginzberg, F. Eckstein, H Zakut   +6 more
openalex   +1 more source

Design, biochemical, biophysical and biological properties of cooperative antisense oligonucleotides [PDF]

, 1995
Ekambar R. Kandimalla, Adrienne Manning, Christopher S. Lathan, Randal A. Byrn, Sudhir Agrawal   +4 more
openalex   +1 more source

erbB-2 antisense oligonucleotides inhibit the proliferation of breast carcinoma cells with erbB-2 oncogene amplification

, 1994
Rámón Colomer, Ruth Lupu, S S Bacus, E P Gelmann   +3 more
openalex   +1 more source

Oligonucleotides Tethered to a Short Polyguanylic Acid Stretch Are Targeted to Macrophages: Enhanced Antiviral Activity of a Vesicular Stomatitis Virus-Specific Antisense Oligonucleotide [PDF]

, 1999
Vikram Prasad, Shehla Hashim, Amitabha Mukhopadhyay, Sandip K. Basu, Rajendra P. Roy   +4 more
openalex   +1 more source

Antisense oligonucleotide inhibition of hepatitis C virus gene expression in transformed hepatocytes [PDF]

, 1996
Ronnie Hanecak, Vickie Brown‐Driver, Maureen Fox, Rumana Azad, S Furusako, Chika Nozaki, Carol M. Ford, Henri Sasmor, Kevin Anderson   +8 more
openalex   +1 more source

Scavenger receptor-mediated delivery of antisense mini-exon phosphorothioate oligonucleotide to Leishmania-infected macrophages [PDF]

, 1997
Gautam Chaudhuri
openalex   +1 more source

Proliferative effect of high glucose is modulated by antisense oligonucleotides against fibronectin in rat endothelial cells [PDF]

, 1997
Sayon Roy, Timothy P. Roth
openalex   +1 more source

Suppression of Intracellular Superoxide Dismutase Activity by Antisense Oligonucleotides Causes Inhibition of Progesterone Production by Rat Luteal Cells1 [PDF]

, 1999
Norihiro Sugino, Shuji Takiguchi, Shiro Kashida, Hisako Takayama, Yoshiaki Yamagata, Yasuhiko Nakamura, Hiroshi Kato   +6 more
openalex   +1 more source