Results 171 to 180 of about 275,477 (365)

Single intraluminal delivery of antisense cdc2 kinase and proliferating-cell nuclear antigen oligonucleotides results in chronic inhibition of neointimal hyperplasia.

, 1993
Ryuichi Morishita, Gary H. Gibbons, Kristin Ellison, Masatoshi Nakajima, L Zhang, Yudai Kaneda, Toshio Ogihara, Victor J. Dzau   +7 more
openalex   +1 more source

Phosphorothioate antisense oligonucleotides against basic fibroblast growth factor inhibit anchorage-dependent and anchorage-independent growth of a malignant glioblastoma cell line. [PDF]

, 1992
Paul R. Murphy, Yuji Sato, Rai Knee
openalex   +1 more source

New insights into applications of base editor in hereditary disorders

Interdisciplinary Medicine, EarlyView.
Abstract Hereditary disorders are a group of diseases caused by genetic mutations or chromosomal variations. Although the incidence of each genetic disorder is relatively low, patients affected by the disease generally experience a range of severe symptoms, including blindness, disability, and even premature death. In addition, the available treatments
Maoping Cai, Linhui Zhang, Liqing Li, Yue Liu, Canbin Lv, Yan Shi, Jianyuan Zhao, Dingwei Ye, Yuanyuan Qu   +8 more
wiley   +1 more source

Antisense oligonucleotides to the p65 subunit of NF-kappa B block CD11b expression and alter adhesion properties of differentiated HL-60 granulocytes [PDF]

, 1993
J A Sokoloski, AC Sartorelli, C.-G. ROSÉN, Ramaswamy Narayanan   +3 more
openalex   +1 more source

LncRNA PVT1 Facilitates Phenotypic Switching of Vascular Smooth Muscle Cells in Intracranial Aneurysms by Recruiting KDM1A to Reduce H3K9me2 Modification

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study explores the differential expression of lncRNA PVT1 in intracranial aneurysms (IAs) and its role in the phenotypic switching of vascular smooth muscle cells (VSMCs). PVT1 and ALOX5 expressions in the serum of IA patients and healthy controls were detected by qRT‐PCR.
Yu‐Fei Cheng, Wei Sun, Yi‐Xia Wang, Jia‐Jie Chen, Ya‐Sen Cao   +4 more
wiley   +1 more source

LncRNA SOX21‐AS1 Promotes the Progression of Pancreatic Cancer by Sponging miR‐9‐3p and Upregulating YOD1

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Pancreatic cancer (PC) is a highly aggressive malignancy of the digestive system. Recent studies have indicated that the long noncoding RNA SOX21‐AS1 is significantly upregulated in PC tissue samples. This study aims to elucidate the biological role and underlying molecular mechanisms of SOX21‐AS1 in PC progression. Quantitative real‐time PCR (
Han‐Bing Xu, Jian‐Tao Han, Cheng‐Peng Zhang, Bin Jiang   +3 more
wiley   +1 more source

A phosphorothioate oligonucleotide blocks reverse transcription via an antisense mechanism [PDF]

, 1994
Claudine Boiziau, Serge Moreau, Jean‐Jacques Toulmé   +2 more
openalex   +1 more source

Recent Advances in Injectable Hydrogel Biotherapeutics for Regenerative Dental Medicine

Macromolecular Bioscience, EarlyView.
This review analyses multifunctional injectable hydrogels, natural or synthetic, physically or chemically crosslinked, that deliver exosomes, stem cells, and other bioactive cues to inflamed or damaged oral tissues. We discuss their immunomodulatory, antimicrobial, angiogenic, and osteogenic capacities, highlighting advances that enable regenerative ...
Renan Dal‐Fabbro, Arwa Daghrery, Caroline Anselmi, Igor Paulino M. Soares, Alexandre Henrique dos Reis‐Prado, Pedro Henrique Chaves de Oliveira, Marco C. Bottino   +6 more
wiley   +1 more source

The role of voltage-gated calcium channel α2δ-1 in the occurrence and development in myofascial orofacial pain

BMC Oral Health
Patients who suffer from myofascial orofacial pain could affect their quality of life deeply. The pathogenesis of pain is still unclear. Our objective was to assess Whether Voltage-gated calcium channel α2δ-1(Cavα2δ-1) is related to myofascial orofacial ...
Yang Lu, Jingfu Wang, Li Li, Xiaodong Zhang   +3 more
doaj   +1 more source

Inhibition of kinesin synthesis and rapid anterograde axonal transport in vivo by an antisense oligonucleotide

, 1993
Anil Amaratunga, Peter J. Morin, K S Kosik, Richard E. Fine   +3 more
openalex   +1 more source