Results 211 to 220 of about 275,477 (365)

Antisense oligonucleotide inhibition of hepatitis C virus gene expression in transformed hepatocytes [PDF]

open access: bronze, 1996
Ronnie Hanecak   +8 more
openalex   +1 more source

Targeting FANCM using the antisense oligonucleotides to treat the ALT-positive cancers. [PDF]

open access: yesMol Ther Nucleic Acids
Naji S   +4 more
europepmc   +1 more source

Polarity Gene PARD6B Promotes Tumor Growth of Colorectal Cancer via Increasing MYC Expression

open access: yesCancer Science, EarlyView.
Partitioning Defective 6B (PARD6B), a polarity gene, functions as a scaffold node for the Par protein complex. In this study, we showed that highly expressed PARD6B could promote CRC growth by upregulating MYC expression while suppressing miR‐34c expression.
Kosuke Hirose   +18 more
wiley   +1 more source

Suppression of Intracellular Superoxide Dismutase Activity by Antisense Oligonucleotides Causes Inhibition of Progesterone Production by Rat Luteal Cells1 [PDF]

open access: bronze, 1999
Norihiro Sugino   +6 more
openalex   +1 more source

Tofersen and other antisense oligonucleotides in ALS. [PDF]

open access: yesTher Adv Neurol Disord
Ludolph A, Wiesenfarth M.
europepmc   +1 more source

Longitudinal Visual Biomarkers in Dominant Optic Atrophy: A Systematic Review and Meta‐Analysis

open access: yesClinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background Dominant Optic Atrophy (DOA) causes slowly progressive visual decline usually beginning in childhood. As new therapies come to clinical trial, the choice of biomarkers to be used as clinical trial endpoints has become a critical question to be addressed. Methods We undertook a systematic review and meta‐analysis of studies reporting
Christopher A. Ovens   +2 more
wiley   +1 more source

Identifying antisense oligonucleotides for targeted inhibition of insulin receptor isoform A. [PDF]

open access: yesFront Oncol
Galifi CA   +6 more
europepmc   +1 more source

Why, how and in whom should we measure levels of lipoprotein(a): A review of the latest evidence and clinical implications

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Lipoprotein(a) [Lp(a)] is a genetically determined, causal risk factor for atherosclerotic cardiovascular disease (ASCVD) and calcific aortic valve disease (CAVD). Despite robust evidence from epidemiological and genetic studies, Lp(a) remains underrecognised in clinical practice due to challenges in measurement, lack of guideline familiarity ...
Alexander C. Razavi   +4 more
wiley   +1 more source

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