Antisense oligonucleotide inhibition of hepatitis C virus gene expression in transformed hepatocytes [PDF]
Ronnie Hanecak+8 more
openalex +1 more source
Targeting FANCM using the antisense oligonucleotides to treat the ALT-positive cancers. [PDF]
Naji S+4 more
europepmc +1 more source
Polarity Gene PARD6B Promotes Tumor Growth of Colorectal Cancer via Increasing MYC Expression
Partitioning Defective 6B (PARD6B), a polarity gene, functions as a scaffold node for the Par protein complex. In this study, we showed that highly expressed PARD6B could promote CRC growth by upregulating MYC expression while suppressing miR‐34c expression.
Kosuke Hirose+18 more
wiley +1 more source
Site-specific DNA cleavage by antisense oligonucleotides covalently linked to phenazine di-N-oxide.
Koki Nagai, Sidney M. Hecht
openalex +1 more source
Suppression of Intracellular Superoxide Dismutase Activity by Antisense Oligonucleotides Causes Inhibition of Progesterone Production by Rat Luteal Cells1 [PDF]
Norihiro Sugino+6 more
openalex +1 more source
Tofersen and other antisense oligonucleotides in ALS. [PDF]
Ludolph A, Wiesenfarth M.
europepmc +1 more source
Longitudinal Visual Biomarkers in Dominant Optic Atrophy: A Systematic Review and Meta‐Analysis
ABSTRACT Background Dominant Optic Atrophy (DOA) causes slowly progressive visual decline usually beginning in childhood. As new therapies come to clinical trial, the choice of biomarkers to be used as clinical trial endpoints has become a critical question to be addressed. Methods We undertook a systematic review and meta‐analysis of studies reporting
Christopher A. Ovens+2 more
wiley +1 more source
Scavenger receptor-mediated delivery of antisense mini-exon phosphorothioate oligonucleotide to Leishmania-infected macrophages [PDF]
Gautam Chaudhuri
openalex +1 more source
Identifying antisense oligonucleotides for targeted inhibition of insulin receptor isoform A. [PDF]
Galifi CA+6 more
europepmc +1 more source
Abstract Lipoprotein(a) [Lp(a)] is a genetically determined, causal risk factor for atherosclerotic cardiovascular disease (ASCVD) and calcific aortic valve disease (CAVD). Despite robust evidence from epidemiological and genetic studies, Lp(a) remains underrecognised in clinical practice due to challenges in measurement, lack of guideline familiarity ...
Alexander C. Razavi+4 more
wiley +1 more source