Neuronal migration plays essential roles in the establishment of mammalian brains, and its impairment causes severe developmental abnormalities and behavioral and cognitive deficits. Here, we report that cadherin‐6 (CDH6), an unusual cadherin molecule containing an RGD integrin‐binding motif in the first extracellular domain, controls the motility of ...
Yuki Hirota+7 more
wiley +1 more source
Modulating immune responses in alopecia: therapeutic insights and potential targets of antisense oligonucleotides. [PDF]
Begum S+6 more
europepmc +1 more source
A Contagious Cause of Rectal Bleeding: Misleading Presentation of Chlamydia trachomatis Infection
United European Gastroenterology Journal, EarlyView.
Irene Marafini+2 more
wiley +1 more source
Blood group O expression in normal tissues and tumors
The H antigen (O blood group), the precursor to A and B blood groups, is expressed on human erythrocytes. Two novel monoclonal antibodies generated using sea lamprey immunization, Tn4‐31L and OmcFL3‐02, specifically detect the H antigen on glycan microarrays, glycoproteins, and human cells.
Ea Kristine Clarisse Tulin+11 more
wiley +1 more source
Properties of circular dumbbell RNA/DNA chimeric oligonucleotides containing antisense phosphodiester oligonucleotides [PDF]
W.-S. Park+4 more
openalex +1 more source
Lipid Nanovesicles in Cancer Treatment: Improving Targeting and Stability of Antisense Oligonucleotides. [PDF]
Ding HY+8 more
europepmc +1 more source
Alternative Splicing Regulation in Metabolic Disorders
ABSTRACT Alternative splicing (AS) is a fundamental mechanism for enhancing transcriptome diversity and regulating gene expression, crucial for various cellular processes and the development of complex traits. This review examines the role of AS in metabolic disorders, including obesity, weight loss, dyslipidemias, and metabolic syndrome.
Dorota Kaminska
wiley +1 more source
RNA G‑Quadruplex Reprogramming with Guanine-Rich Antisense Oligonucleotides Inhibits Monoamine Oxidase B's Translation. [PDF]
Turcotte MA, Perreault JP.
europepmc +1 more source
CsMYB213‐CsbHLH35 module regulates theanine biosynthesis in tea plants (Camellia sinensis L.)
Summary Theanine is a non‐protein free amino acid accumulated in tea plant leaves and makes a major contribution to the unique umami and sweet taste and a multitude of human health benefits of tea. However, its biosynthesis and transcriptional regulation in tea plant leaves remain to be fully understood.
Nianci Xie+10 more
wiley +1 more source
Clinical Applications of Antisense Oligonucleotides in Cancer: A Focus on Glioblastoma. [PDF]
Khuu A+4 more
europepmc +1 more source