Results 251 to 260 of about 124,170 (327)

Delivering LINE1 antisense oligonucleotides via endothelial targeting extracellular vesicles to ameliorate myocardial infarction-induced cardiac senescence. [PDF]

Bioact Mater
Fu E, Pan K, Hinnant B, Chen S, Han Z, Guo Z, Han ZC, Li Q, Li Z.   +8 more
europepmc   +1 more source

Antisense Bcl-x oligonucleotide induces apoptosis and prevents arterial neointimal formation in murine cardiac allografts

, 2000
Jun‐ichi Suzuki
openalex   +1 more source

The role of UPR‐related long noncoding RNAs in development of endocrine resistance in breast cancer

International Journal of Cancer, Volume 157, Issue 12, Page 2434-2446, 15 December 2025.
Abstract Breast cancer patients who express estrogen receptor α (ER) typically receive endocrine therapy as a first‐line treatment. Most ER‐positive breast cancer patients initially respond to endocrine therapy, but up to 40% of patients develop resistance over time, and the main mechanism is aberrant activation of ER signaling pathways.
Wen Liu, Sahil Gupta, Sanjeev Gupta
wiley   +1 more source

Personalized allele-specific antisense oligonucleotides for GNAO1-neurodevelopmental disorder. [PDF]

Mol Ther Nucleic Acids
Shomer I, Mor N, Raviv S, Budick-Harmelin N, Matchevich T, Avkin-Nachum S, Rais Y, Haffner-Krausz R, Haimovich A, Ziv A, Fluss R, Ben-Ze'ev B, Heimer G, Silachev DN, Katanaev VL, Dominissini D.   +15 more
europepmc   +1 more source

Dose-dependent reduction of chronic dextransulfate sodium (DSS)-induced colitis in mice treated with TNF-a antisense oligonucleotide (ISIS 25302)

, 2000
Brenda F. Baker, S. Murthy, Anne Flanigan, Andy Siwkowski, Madeline Butler, Nickolas M. Dean   +5 more
openalex   +1 more source

Spectrometry and Its Application for the Detection of RNA‐Binding Proteins: Advancements, Techniques and Challenges

Analytical Science Advances, Volume 6, Issue 2, December 2025.
ABSTRACT Spectrometry is a fascinating field of analytical science that encompasses a range of techniques used to study the interaction between electromagnetic radiation and matter. Through the measurement and analysis of various radiations, spectrometry provides valuable insights into the composition, structure and properties of different substances ...
Mina Moradi, Zahra Farjami, Mohammad Mehdi Akbarin   +2 more
wiley   +1 more source

Therapeutic Antisense Oligonucleotides in Oncology: From Bench to Bedside. [PDF]

Cancers (Basel)
Çakan E, Lara OD, Szymanowska A, Bayraktar E, Chavez-Reyes A, Lopez-Berestein G, Amero P, Rodriguez-Aguayo C.   +7 more
europepmc   +1 more source

Computational Framework for High Copy‐Number Probe Selection and Cross‐Binding Reduction

Analytical Science Advances, Volume 6, Issue 2, December 2025.
ABSTRACT DNA probe design plays a critical role in biosensor‐based disease diagnostics, gene expression analysis and environmental monitoring. Traditional probe designs primarily target lower‐copy genetic sequences, often leading to low detection sensitivity due to limited hybridization events.
Younghwan Kim, Swomitra Kumar Mohanty
wiley   +1 more source

Multispanning membrane protein SIDT2 increases knockdown activity of gapmer antisense oligonucleotides. [PDF]

Sci Rep
Kusumoto K, Sasaki K, Uchida Y, Utsumi A, Yoshida T, Obika S, Inoue T, Okuhira K.   +7 more
europepmc   +1 more source

Rewriting the MASLD‐associated hepatocellular carcinoma script: Targeting epigenetics and metabolism

International Journal of Cancer, Volume 157, Issue 10, Page 1991-2003, 15 November 2025.
Abstract Abnormal epigenetic patterns are crucial for the progression of metabolic‐associated steatotic liver disease (MASLD) and hepatocellular carcinoma (HCC) development. Recent research focused on the interplay between epigenetics and altered metabolic pathways in HCC from MASLD, suggesting that the reversibility of epigenetic changes offers ...
Chiara Aiello, Eric Felli, Teresa Musarra, Lorenzo Nevi, Annamaria Altomare, Jordi Gracia‐Sancho, Andrea Baiocchini, Simone Carotti   +7 more
wiley   +1 more source