Results 101 to 110 of about 61,173 (287)

An Aptamer‐Based EXACT Anticoagulant as a Sustainable, Animal‐Free Alternative to Unfractionated Heparin

Advanced Science, Volume 13, Issue 4, 19 January 2026.
By simply conjugating thrombin's active‐site inhibitor, dabigatran, with an exosite inhibitor, aptamer HD1, the resulting EXosite‐ACTive site (EXACT) inhibitors show two orders of magnitude higher potency and selectivity via synergistic binding, while maintaining the aptamer's antidote‐reversible trait, yielding a potential substitute for the animal ...
Haixiang Yu, George Pitoc, Manqi Zhang, Jeffrey Clancy, James Frederiksen, Amy Yan, Samuel Francis, Rebecca Sullenger, Rachel Rempel, Susannah Gammell, Jillian Caiazzi, Bruce A. Sullenger   +11 more
wiley   +1 more source

Houston, we have a problem: Coagulation concerns during long‐term spaceflight

Experimental Physiology, EarlyView.
Lewis Fall, Damian M. Bailey
wiley   +1 more source

Facts and Misfacts on D‐Dimer Testing. Consensus Guidance From the Italian Society on Thrombosis and Hemostasis (SISET)

American Journal of Hematology, Volume 101, Issue 1, Page 97-109, January 2026.
ABSTRACT D‐dimer defines degradation products derived from the proteolysis mediated by plasmin on cross‐linked fibrin. The evidence‐based use of D‐dimer in some conditions has been consolidated. Currently, however, there is an entrenched prescription of D‐dimer testing to screen otherwise healthy subjects that may induce prescribing physicians to start
Armando Tripodi, Walter Ageno, Luca Barcella, Antonio Coppola, Marcello Di Nisio, Massimo Franchini, Monia Marchetti, Rossella Marcucci, Marco Marietta, Pasquale Pignatelli, Domenico Prisco, Valerio De Stefano   +11 more
wiley   +1 more source

Biomarkers in patients with clinical signs of mild cognitive impairment or mild Alzheimer's disease but without amyloid deposits on positron emission tomography: Results from Bio‐Hermes Study participants

Alzheimer's &Dementia, Volume 22, Issue 1, January 2026.
Abstract INTRODUCTION Alzheimer's disease (AD) study participants may present with cognitive impairment who do not have brain amyloid deposits (Aβ−). Identifying predictive biomarkers for non‐amyloid‐related CI may provide better screening tests for trials seeking only CI Aβ+ participants and new therapy targets.
Richard C. Mohs, Douglas W. Beauregard, Lynne Hughes, Cyndy B. Cordell, Allan I. Levey, Saima Rathore, Nicholas T. Seyfried, Erik C. B. Johnson, Jessie Nicodemus‐Johnson, Joshua Christensen, Robin Wolz, John Dwyer   +11 more
wiley   +1 more source

Bilateral Ileofemoral Thrombophlebitis after Ten Contraceptive Pills in a 25-Year-Old Woman with Antithrombin III Deficiency [PDF]

, 1988
Antonio Girolami, F Stevanato, Anna Rosa Lazzaro   +2 more
openalex   +1 more source

Proteomic and Ubiquitinated Proteome Insights Into ER Stress Responses in Chinese Hamster Ovary Cells Under Mild Hypothermic Conditions

Biotechnology and Bioengineering, Volume 123, Issue 1, Page 5-25, January 2026.
Proteomic analysis of CHO cells under mild hypothermia (31°C) reveals ER stress responses, ubiquitination dynamics, and adaptive mechanisms. Magnetic immuno‐affinity enrichment and mass spectrometry highlight protein regulation differences in non‐producer versus producer cells, offering insights for optimising biopharmaceutical production of IgG1 and ...
David Ryan, Christiana‐Kondylo Sideri, Michael Henry, Selvaprakash Karuppuchamy, Esen Efeoglu, Paula Meleady   +5 more
wiley   +1 more source

Outcomes of Cerebral Venous Thrombosis in Patients With Myeloproliferative Neoplasms from a U.S. Nationwide Hospitalization Study

eJHaem, Volume 7, Issue 1, February 2026.
Nikhil Vojjala, Raj Shah, Viktoriya Gibatova, Lakshmi Kattamuri, Shubham Agrawal, Geetha Krishnamoorthy, Rushad Patell   +6 more
wiley   +1 more source

Coagulation Pathways as Determinants of Acute Subdural Hematoma Resolution: Genetic Evidence From Human Data

CNS Neuroscience &Therapeutics, Volume 32, Issue 1, January 2026.
This study applied a two‐sample Mendelian randomization framework to investigate the causal effects of coagulation pathways on the spontaneous resolution of acute subdural hematoma (ASDH). Genetic variants influencing coagulation traits were analyzed using GWAS data as instrumental variables.
Qizhong Wu, Tingting Xu, Bo Tan
wiley   +1 more source

Modulation of glycosaminoglycan production and antithrombin III binding by cultured aortic endothelial cells treated with 4-methylumbelliferyl-beta-D-xyloside. [PDF]

, 1987
Kazuyuki Shimada, Takeaki Ozawa
openalex   +1 more source

Association Between Thrombin–Antithrombin Complex and Acute Kidney Injury After Pediatric Cardiopulmonary Bypass Surgery: A Single-Center Retrospective Observational Study [PDF]

, 2023
Sakura Minami, Hiroyuki Nagafuchi, Kaori Yamada, Takeru Abe, Ichiro Takeuchi   +4 more
openalex   +1 more source