Results 211 to 220 of about 37,722 (251)
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Pasteurization of antithrombin without generation of the prelatent form of antithrombin
Protein Expression and Purification, 2004Human antithrombin (AT) is the major inhibitor of blood coagulation and has also been shown to exert anti-inflammatory and anti-angiogenic effects. Pasteurization of pharmaceutical AT products is usually performed at 60 degrees C for 10h in the presence of sodium citrate as stabilizer, sometimes in combination with sucrose.
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Human Fibrinopeptides as Antithrombins
Thrombosis and Haemostasis, 1973SummaryHuman fibrinopeptides have been isolated from purified human fibrinogen and investigations performed on their reactions with thrombin and platelets. Fibrinopeptides A and B had an inhibitory action against the proteolytic action of thrombin but fibrinopeptide A did not impair the esterolytic activity of the enzyme.
J J, Gorman, P A, Castaldi
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ANTITHROMBIN IN INFANCY AND CHILDHOOD
Acta Paediatrica, 1975ABSTRACT: Teger‐Nilsson, A‐C. (Department of Clinical Chemistry, Department of Pediatrics, and Department of Blood Coagulation Research, Karolinska sjukhuset, Stockholm). Antithrombin in infancy and childhood. Acta Pediatr Scand, 64:624, 1975.–Anti‐thrombin III was measured immunologically, and antithrombin activity was measured with aid of a new ...
A, Catrine, T, Nilsson
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British Journal of Haematology, 1984
SummaryAntithrombin III (AT‐III) heparin cofactor activity and its antigen levels have been determined in 106 plasma samples from 42 term and preterm neonates. In contrast to healthy adult controls, a reduced activity/antigen (act/ag) ratio (ranging from 0‐26 to 0‐86) was observed in 90% of the samples and was independent of the state of health of the ...
Peters, M. +5 more
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SummaryAntithrombin III (AT‐III) heparin cofactor activity and its antigen levels have been determined in 106 plasma samples from 42 term and preterm neonates. In contrast to healthy adult controls, a reduced activity/antigen (act/ag) ratio (ranging from 0‐26 to 0‐86) was observed in 90% of the samples and was independent of the state of health of the ...
Peters, M. +5 more
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Archives of Surgery, 1979
To the Editor .—The white clot syndrome recently reported by Towne et al 1 is disturbing. The complications of therapy with heparin are a problem not only for physician and patient, but for the clinical pharmacist, who is often called on to explain them.
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To the Editor .—The white clot syndrome recently reported by Towne et al 1 is disturbing. The complications of therapy with heparin are a problem not only for physician and patient, but for the clinical pharmacist, who is often called on to explain them.
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Blood Reviews, 1988
A moderate reduction of plasma antithrombin activity is an uncommon but clinically important cause of severe thromboembolic disease. In recent years the molecule responsible for the major part of this activity (antithrombin III) has been extensively characterised and the mode of inheritance of familial deficiencies worked out.
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A moderate reduction of plasma antithrombin activity is an uncommon but clinically important cause of severe thromboembolic disease. In recent years the molecule responsible for the major part of this activity (antithrombin III) has been extensively characterised and the mode of inheritance of familial deficiencies worked out.
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Mild Antithrombin Deficiency and Risk of Recurrent Venous Thromboembolism
Circulation, 2014Matteo Nicola Dario Di Minno +2 more
exaly
Issues in the Diagnosis and Management of Hereditary Antithrombin Deficiency
Annals of Pharmacotherapy, 2016Kenneth A Bauer
exaly

