Results 31 to 40 of about 61,173 (287)

Sepsis-Associated DIC with Decreased Levels of Antithrombin and Fibrinogen is the Target for Combination Therapy with Thrombomodulin Alfa and Antithrombin

TH Open, 2023
Background Disseminated intravascular coagulation (DIC) is not a homogeneous condition, but rather includes heterogeneous conditions, and its pathophysiology and outcome vary considerably depending on the background.
Hideo Wada, Kazuo Kawasugi, Goichi Honda, Noriaki Kawano, Toshimasa Uchiyama, Seiji Madoiwa, Naoki Takezako, Kei Suzuki, Yoshinobu Seki, Takayuki Ikezoe, Toshiaki Iba, Kohji Okamoto   +11 more
doaj   +1 more source

Cross-Species Analysis of Glycosaminoglycan Binding Proteins Reveals Some Animal Models Are “More Equal” than Others

Molecules, 2019
Glycosaminoglycan (GAG) mimetics are synthetic or semi-synthetic analogues of heparin or heparan sulfate, which are designed to interact with GAG binding sites on proteins.
Eric D. Boittier, Neha S. Gandhi, Vito Ferro, Deirdre R. Coombe   +3 more
doaj   +1 more source

Hypercoagulability in Patients with Non-Alcoholic Fatty Liver Disease (NAFLD): Causes and Consequences

Biomedicines, 2022
Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease, and it is anticipated that it could become even more prevalent in parallel with an increase in the incidence of metabolic diseases closely related to NAFLD, such as ...
Armando Tripodi, Rosa Lombardi, Massimo Primignani, Vincenzo La Mura, Flora Peyvandi, Anna L. Fracanzani   +5 more
doaj   +1 more source

Prothrombin Complex Concentrate-induced Disseminated Intravascular Coagulation Can Be Prevented by Coadministering Antithrombin in a Porcine Trauma Model.

Anesthesiology, 2019
WHAT WE ALREADY KNOW ABOUT THIS TOPIC Prothrombin complex concentrates are increasingly used as part of bleeding management algorithms in surgery and traumaThere are potential risks of thromboembolic complications and disseminated intravascular ...
O. Grottke, M. Honickel, T. Braunschweig, Anne Reichel, H. Schöchl, R. Rossaint   +5 more
semanticscholar   +1 more source

Short Term Treatment Monitoring of Renal and Inflammatory Biomarkers with Naturally Occurring Leishmaniosis: A Cohort Study of 30 Dogs

Veterinary Sciences
Various inflammatory and renal biomarkers have already been assessed for monitoring the response to anti-leishmanial therapy in canine leishmaniosis. This study assessed the parasite load, various inflammatory and renal biomarkers pre- and post-treatment,
Valeria Pantaleo, Tommaso Furlanello, Michela Campigli, Laura Ventura, Laia Solano-Gallego   +4 more
doaj   +1 more source

Impact of Different Treatments for Disseminated Intravascular Coagulation on Patients with or without Biliary Drainage for Severe Biliary Tract Infection

Open Access Emergency Medicine, 2023
Makoto Kobayashi,1 Shun Takai,2 Kyohei Sakurai,3 Yoshimatsu Ehama3 1Director of Surgery and Intensive Care Center, Hakodate Goryokaku Hospital, Hakodate City, Hokkaido, Japan; 2Division of Gastroenterology, Hakodate Goryokaku Hospital, Hakodate City ...
Kobayashi M, Takai S, Sakurai K, Ehama Y
doaj  

Influence of Fucoidans on Hemostatic System

Marine Drugs, 2013
Three structurally different fucoidans from the brown seaweeds Saccharina latissima (SL), Fucus vesiculosus (FV), and Cladosiphon okamuranus (CO), two chemically modified fucoidans with a higher degree of sulfation (SL-S, CO-S), and a synthetic totally ...
Mikhail V. Kiselevskiy, Anatolii I. Usov, Marina E. Preobrazhenskaya, Vadim B. Krylov, Albina V. Madzhuga, Oksana V. Somonova, Anna L. Elizarova, Maria I. Bilan, Ksenia A. Zyuzina, Natalia A. Ushakova, Nadezhda E. Ustyuzhanina, Nikolay E. Nifantiev   +11 more
doaj   +1 more source

Association of COVID-19 Vaccines ChAdOx1-S and BNT162b2 with Circulating Levels of Coagulation Factors and Antithrombin

Vaccines, 2022
Background: Severe coronavirus disease 2019 (COVID-19) is associated with increased risk of thrombosis and thromboembolism. Exposure to COVID-19 vaccines is also associated with immune thrombotic thrombocytopenia, ischemic stroke, intracerebral ...
Amal Hasan, Hossein Arefanian, Arshad Mohamed Channanath, Irina AlKhairi, Preethi Cherian, Sriraman Devarajan, Thangavel Alphonse Thanaraj, Mohamed Abu-Farha, Jehad Abubaker, Fahd Al-Mulla   +9 more
doaj   +1 more source

SerpinC1/Antithrombin III in kidney-related diseases

Clinical science, 2017
The gene SerpinC1 encodes a serine protease inhibitor named antithrombin III (ATIII). This protease demonstrates both anticoagulant and anti-inflammatory action.
Zeyuan Lu, Feng Wang, Mingyu Liang
semanticscholar   +1 more source

Dexamethasone Preconditioning in Cardiac Procedures Reduces Decreased Antithrombin Activity and Is Associated to Beneficial Outcomes: Role of Endothelium

Frontiers in Pharmacology, 2018
Introduction: Decreased antithrombin (AT) activity in patients scheduled for cardiovascular surgery under cardiopulmonary bypass (CPB) is related to increased postoperative complications and hospitalization time.
Vicente Muedra, Vicente Muedra, Lucrecia Moreno, Vicente Rodilla, Cristina Arce, Cristina Arce, Fermi Montó, Fermi Montó, Águeda Blázquez, Paloma Pérez, Pilar D’Ocón, Pilar D’Ocón   +11 more
doaj   +1 more source