Results 11 to 20 of about 57,561 (211)

Pregnancy Complicated by Hereditary Antithrombin Deficiency: A Case Study and Insights From the Literature. [PDF]

open access: yesClin Case Rep
ABSTRACT A pregnant woman with hereditary antithrombin deficiency was managed with adjusted‐dose LMWH throughout pregnancy, monitoring D‐dimer and anti‐Xa activity, successfully preventing thrombosis and hemorrhage.
Zhao Y, Yin J, Song J, Zhao Y, Zhang Y.
europepmc   +2 more sources

The Influence of Calcium on the Binding of Antithrombin by Antithrombin Inhibitor.

open access: yesExperimental Biology and Medicine, 1966
Summary and Conclusions1. The reaction between antithrombin and inhibitor has a quantitative requirement for calcium. 2. Calcium is not the inhibitor of antithrombin. 3. Calcium is not required for neutralization of thrombin by antithrombin.
H H, Henstell, M, Kligerman
openaire   +2 more sources

Anticoagulation Management and Antithrombin Supplementation Practice during Veno-venous Extracorporeal Membrane Oxygenation

open access: yesAnesthesiology, 2019
Background: There is a lack of consensus on how to manage anticoagulation during veno-venous extracorporeal membrane oxygenation, including antithrombin monitoring and supplementation.
A. Protti   +4 more
semanticscholar   +1 more source

THROMBOTECT – a randomized study comparing low molecular weight heparin, antithrombin and unfractionated heparin for thromboprophylaxis during induction therapy of acute lymphoblastic leukemia in children and adolescents

open access: yesHaematologica, 2018
Thromboembolism is a serious complication of induction therapy for childhood acute lymphoblastic leukemia. We prospectively compared the efficacy and safety of antithrombotic interventions in the consecutive leukemia trials ALL-BFM 2000 and AIEOP-BFM ALL
J. Greiner   +18 more
semanticscholar   +1 more source

A test for antithrombin in the blood [PDF]

open access: yesExperimental Biology and Medicine, 1914
A test is described for the estimation of antithrombin in the blood. The chief advantage of the test is that it is simple, and does not require the preparation of fibrinogen and of thrombin, which are difficult to prepare and to maintain in a pure state.
openaire   +2 more sources

Establishment of Reference Intervals for Thrombus Biomarkers in a Single-Center Chinese Population Using Indirect Methods. [PDF]

open access: yesJ Clin Lab Anal
This study established and validated comprehensive RIs for four key thrombus biomarkers (TAT, PIC, TM, and t‐PAIC) in a Chinese population using the Hoffmann and Bhattacharya indirect methods on a large clinical dataset. The tailored RIs offer a practical tool for early detection and risk assessment of thrombotic diseases, supporting more precise and ...
Zhang L, Hu Q, Chen Y, Yuan H.
europepmc   +2 more sources

SerpinC1/Antithrombin III in kidney-related diseases

open access: yesClinical science, 2017
The gene SerpinC1 encodes a serine protease inhibitor named antithrombin III (ATIII). This protease demonstrates both anticoagulant and anti-inflammatory action.
Zeyuan Lu, Feng Wang, Mingyu Liang
semanticscholar   +1 more source

Optimal Antithrombin Activity Threshold for Initiating Antithrombin Supplementation in Patients With Sepsis-Induced Disseminated Intravascular Coagulation: A Multicenter Retrospective Observational Study

open access: yesClinical and applied thrombosis/hemostasis, 2018
Low-dose antithrombin supplementation therapy (1500 IU/d for 3 days) improves outcomes in patients with sepsis-induced disseminated intravascular coagulation (DIC).
M. Hayakawa   +3 more
semanticscholar   +1 more source

In Vivo Monitoring of Thrombo‐Inflammatory Biomarkers via Molecularly Imprinted Polymer‐Integrated Hydrogel Microneedles

open access: yesAdvanced Materials, EarlyView.
A wearable electrochemical microneedle patch integrates Prussian Blue redox transduction with molecularly imprinted polymer recognition for reagent‐free sampling and detection of thrombo‐inflammatory biomarkers in dermal interstitial fluid. The platform tracks thrombin and inflammatory cytokines with sensitive in vitro, ex vivo, and in vivo performance,
Mahmoud Ayman Saleh   +11 more
wiley   +1 more source

High levels of latent antithrombin in plasma from patients with antithrombin deficiency

open access: yesThrombosis and Haemostasis, 2017
Summary Antithrombin is an anticoagulant serpin that efficiently inhibits multiple procoagulant proteases. The cost for the structural flexibility required for this function is the vulnerability to mutations that impact its folding pathway.
M. E. de la Morena-Barrio   +14 more
semanticscholar   +1 more source

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