Results 31 to 40 of about 37,722 (251)

beta-Antithrombin, subtype of antithrombin deficiency and the risk of venous thromboembolism in hereditary antithrombin deficiency: A family cohort study

, 2018
Hereditary antithrombin deficiency is associated with a high incidence of venous thromboembolism (VTE), but VTE risk differs between families. Beta-antithrombin is reported to be the most active isoform of antithrombin in vivo.
Lukens, Michael V., André B. Mulder, Croles, Frederik Nanne, Mulder, Andre B., Meijer, Karina, Karina Meijer, Meijer, Karina; id_orcid, René Mulder, Mulder, Rene, Michaël V. Lukens, Frederik Nanne Croles   +10 more
core   +1 more source

Antithrombin I Activity

, 1959
Summary1. Our experiments demonstrate that antithrombin I interferes considerably in the thrombin inhibitor determination described by Jürgens. A similar interference can be suspected in the immediate antithrombin determinations as described by other ...
Marc Verstraete, Carl Vermylen
core   +1 more source

In vivo genome editing for hemophilia B therapy by the combination of rebalancing and therapeutic gene knockin using a viral and non-viral vector

Molecular Therapy: Nucleic Acids, 2023
Recent therapeutic strategies for hemophilia include long-term therapeutic gene expression using adeno-associated virus (AAV) and rebalancing therapy via the downregulation of anticoagulant pathways.
Jeong Hyeon Lee, Jeong Pil Han, Dong Woo Song, Geon Seong Lee, Beom Seok Choi, MinJeong Kim, Yeji Lee, Seokjoong Kim, Hyukjin Lee, Su Cheong Yeom   +9 more
doaj   +1 more source

Antithrombin-III for New Coronavirus Infection (COVID-19) Under Conditions of Extracorporeal Membrane Oxygenation (Clinical Observation)

Неотложная медицинская помощь, 2022
COVID-19 is a disease that, in addition to respiratory failure, leads to thrombosis and bleeding due to coagulation disorders. Extracorporeal membrane oxygenation (ECMO), required in cases of a deterioration of gas exchange function of the lungs ...
S. V. Zhuravel, V. V. Vladimirov, P. V. Gavrilov, I. V. Ivanov, S. S. Petrikov, K. A. Popugayev, A. M. Talyzin   +6 more
doaj   +1 more source

Assessing the Sensitivity and the Clinical Impact of the 2023 American College of Rheumatology/EULAR Classification Criteria in Obstetric Antiphospholid Syndrome: Findings From a Multicenter Italian Cohort With a Long‐Term Follow‐Up

Arthritis Care &Research, EarlyView.
Objective The aim of this study was to evaluate the sensitivity of the 2023 American College of Rheumatology (ACR)/EULAR classification criteria for antiphospholipid syndrome (APS) in a real‐world cohort of women diagnosed with primary obstetric APS (oAPS) and to assess their ability to identify patients at risk of future pregnancy complications ...
Francesca Ruffilli, Cecilia Nalli, Francesca Crisafulli, Carlo Garaffoni, Marcello Govoni, Giulia Voltarel, Alba C. Pozzi, Beatrice Maranini, Ettore Silvagni, Alessandra Bortoluzzi, Angela Tincani   +10 more
wiley   +1 more source

Engineered Heparinized GQDS/HPEI–Polyamide Membrane for Bilirubin Removal via One Step Anti Coagulation

Advanced Materials Interfaces, EarlyView.
A multifunctional heparinized polyamide membrane embedded with graphene quantum dots (GQDs) and hyperbranched polyethyleneimine (HPEI) is engineered for efficient bilirubin removal via a one‐step anticoagulation–adsorption process. The membrane demonstrates enhanced hemocompatibility, prolonged clotting times, and high bilirubin adsorption capacity ...
Abdur Rehman Mushtaq Ahmad, Maria Wasim, Aneela Sabir, Muhammad Shafiq, Syed Abdul Basit Shah, Maoz Maoz, Vanni Lughi   +6 more
wiley   +1 more source

Natural anticoagulant protein levels in patients with transfusion-dependent thalassemia in Nineveh province

Iraqi Journal of Hematology
BACKGROUND: Protein C (PC), protein S (PS), and antithrombin levels dramatically reduced in thalassemic patients, particularly those with splenectomies and few transfusions, indicating a significant involvement in hypercoagulability.
Samar Saleh Saadi
doaj   +1 more source

FGL2‐HDAC11 Drives Immunothrombosis via NETs‐Mediated Endothelial Capillarization in MASLD Fibrosis

Advanced Science, EarlyView.
ABSTRACT Metabolic dysfunction–associated steatotic liver disease (MASLD) is frequently accompanied by hepatic fibrosis and systemic cardiovascular complications; however, the mechanistic interplay between coagulation abnormalities and disease progression remains poorly defined.
Xitang Li, Junjian Hu, Suping Hai, Peng Hu, Wenhui Wu, Qiang Gao, Binghui Yu, Feiyang Xu, Xizhe Zheng, Qianting Guan, Huiling Xiang, Dong Xi, Weiming Yan, Peng Wang, Bin‐hao Zhang, Qin Ning, Xiaojing Wang   +16 more
wiley   +1 more source

1E05: Plasma Alpha Antithrombin-Iii

, 2000
Antithrombin is a member of the serpin family of protease inhibitors and the major inhibitor of the blood coagulation cascade. It is unique amongst the serpins in that it circulates in a conformation that is inactive against its target proteases ...
Skinner, R., Carrell, R. W., McCoy, A. J., Abrahams, J.-P., Pei, X. Y.   +4 more
core   +1 more source

Changes in Serum Proteins in Cats with Obesity: A Proteomic Approach

Animals
Obesity is defined as the excessive accumulation of adipose tissue and is currently the most common disease in cats. Similarly to humans, obesity negatively impacts the health and welfare of cats, predisposing them to many other disorders.
Esmeralda Cañadas-Vidal, Alberto Muñoz-Prieto, Dina Rešetar Maslov, Ivana Rubić, Juan C. González-Sánchez, Juan D. Garcia-Martinez, José J. Ceron, Vladimir Mrljak, Luis Pardo-Marin, Silvia Martinez-Subiela, Asta Tvarijonaviciute   +10 more
doaj   +1 more source