Results 81 to 90 of about 2,459,862 (252)

Anticoagulation methods used and role of antithrombin III level monitoring in children on continuous renal replacement therapy: an observational cross-sectional study

Egyptian Pediatric Association Gazette
Background In critically ill cases, CRRT is a renal replacement intervention. The most common reason why CRRT terminates prematurely (non-electively) is clotting in the extracorporeal circuit, more especially in the filter.
Fatina Ibrahim Fadel, Hafez Mahmoud Bazaraa, Shahira Kamal Anis, Noha Mahmoud Mohamed, Yosra Aboelnaga Fahmy   +4 more
doaj   +1 more source

Levels of Natural Anticoagulants Protein C, Protein S and Antithrombin III in Patients with Solid Malignancies

Journal of Rawalpindi Medical College, 2014
Background: To estimate plasma levels of natural anticoagulants, i.e., Protein C, Protein S and Antithrombin III in patients with solid malignancies Methods: A cross-sectional study was conducted wherein plasma levels of Protein C,S and Antithrombin III (
Samina T.Amanat
doaj   +2 more sources

Heparin resistance management during cardiac surgery: a literature review and future directions

The Journal of ExtraCorporeal Technology
Introduction: Heparin, a commonly used anticoagulant in cardiac surgery, binds to antithrombin III (ATIII) to prevent clot formation. However, heparin resistance (HR) can complicate surgical procedures, leading to increased thromboembolic risks and ...
Butt Salman Pervaiz, Kakar Vivek, Kumar Arun, Razzaq Nabeel, Saleem Yasir, Ali Babar, Raposo Nuno, Ashiq Fazil, Ghori Arshad, Anderson Philip, Srivatav Nilesh, Aljabery Yazan, Abdulaziz Salman, Darr Umer, Bhatnagar Gopal   +14 more
doaj   +1 more source

Trends in physiological coagulation factors in Japanese patients receiving novel oral anticoagulants

Journal of Arrhythmia, 2017
Background: Little is known about physiological anticoagulation effects via antithrombin III (AT III) and protein C/S (PC/PS) in patients using new oral anticoagulants (NOACs).
Tomoyuki Nagao, MD, Hiroshi Hunakubo, MD, Mayu Suzuki, MD, Takashi Kataoka, MD, Satoshi Okumura, MD, Norihiro Shinoda, MD, PhD, Ken Harada, MD, PhD, Bunichi Kato, MD, PhD, Masataka Kato, MD, Nobuyuki Marui, MD, PhD, Shinichi Sakai, MD, Tetsuya Amano, MD, PhD, Toyoaki Murohara, MD, PhD   +12 more
doaj   +1 more source

Combined Antithrombin and Heparin Supplementation to Blood for Restoring Heparin Responsiveness After Andexanet Alfa Exposure: An In Vitro Model

eJHaem, Volume 7, Issue 1, February 2026.
ABSTRACT Background: Andexanet alfa, a Gla‐domainless mutant factor Xa (GDXa), reverses oral FXa inhibitors but can cause severe heparin resistance during cardiopulmonary bypass (CPB). Antithrombin (AT) supplementation may mitigate this effect, though dosing evidence is limited. Methods We evaluated in vitro the effectiveness of combined heparin and AT
Amir L. Butt, Hisako Okada, Kofi B. Vandyck, Nana Toyoda, Shinobu Itagaki, Kenneth E. Stewart, Kenichi A. Tanaka   +6 more
wiley   +1 more source

Clinical Outcomes of Patients Hospitalized for Conventional Pacemaker Implantation With Protein‐Energy Malnutrition

Journal of Arrhythmia, Volume 42, Issue 1, February 2026.
Protein‐energy malnutrition (PEM) was linked to higher in‐hospital mortality, longer hospital stays, and increased complications in patients undergoing pacemaker implantation. ABSTRACT Introduction The impact of protein‐energy malnutrition (PEM) on patients hospitalized for conventional pacemaker implantation remains poorly understood.
Phuuwadith Wattanachayakul, Pojsakorn Danpanichkul, Chalothorn Wannaphut, Hamza Tahir, John Malin, Thanathip Suenghataiphorn, Kanokphong Suparan, Aman Amanullah   +7 more
wiley   +1 more source

Progress in RNA‐Targeted Therapeutics for Human Diseases

MedComm, Volume 7, Issue 2, February 2026.
RNA‐targeted therapies are revolutionizing molecular medicine by transitioning from a “protein‐centric” focus to an “RNA‐regulatory network” approach. Leveraging RNA's diverse roles in gene regulation, signaling, and epigenetic modifications, advanced platforms such as ASOs, siRNA, miRNA, mRNA, aptamers, shRNA, and CRISPR/Cas systems are enabling ...
Wangzheqi Zhang, Aimin Jiang, Bin‐Kui Jia, Yuming Jin, Yinghu Chen, Zhaoyu Li, Yan Liao, Haoling Zhang, Zhiheng Lin, Xiao Fang, Linhui Wang   +10 more
wiley   +1 more source

Role of Prothrombin and Methylenetetrahydrofolate Reductase Gene Polymorphisms as well as Thrombophilia Markers, as Risk Factors for Unexplained Recurrent Miscarriage: A Case-Control Study [PDF]

International Journal of Fertility and Sterility
Background: Unexplained recurrent miscarriage (RM) is still an unsolved reproductive health problem. Inheritedthrombophilias have been one of the causes.
Zeinab Ahmed Abd Elhameed, Omar M Shaaban, Hanan G Abd Elazeem, Azza Abouelfadle, Tarek Farghaly, Ghada Mahran, Mohamed Ismail Seddik   +6 more
doaj   +1 more source

Is either arterial or venous antithrombin III level linked to outcome in elderly males versus females with severe sepsis?

Asian Journal of Medical Sciences, 2014
Objectives: We aimed to study arterial and venous ATIII levels, in elderly males and females with severe sepsis, and their impact upon the patients’ outcomes.
Nermien N Adly
doaj   +1 more source

Houston, we have a problem: Coagulation concerns during long‐term spaceflight

Experimental Physiology, EarlyView.
Lewis Fall, Damian M. Bailey
wiley   +1 more source