Results 101 to 110 of about 1,671 (202)

Nature Inspired Delivery Vehicles for CRISPR‐Based Genome Editing

Small, Volume 22, Issue 16, 17 March 2026.
The review highlights nature‐inspired nanocarriers for CRISPR delivery, emphasizing viral vectors, extracellular vesicles, liposomes, and lipid nanoparticles. It discusses their roles in improving specificity, minimizing immunogenicity, and overcoming barriers in genome editing. Recent advancements, challenges, and therapeutic applications are explored,
Elizabeth Maria Clarissa, Mamata Karmacharya, Hyunmin Choi, Sumit Kumar, Yoon‐Kyoung Cho   +4 more
wiley   +1 more source

Clinical Significance of Microembolic Signal Detection in Acute Ischemic Stroke: Insights Into Ongoing Cerebral Embolization and Occult Etiologies

European Journal of Neurology, Volume 33, Issue 3, March 2026.
In this prospective study of anterior circulation AIS patients, microembolic signals (MES) were detected in 16% of cases, absent in lacunar stroke. MES presence was linked to multiple‐territory infarcts, newly diagnosed atrial fibrillation, and cancer‐associated stroke.
Eleni Bakola, Lina Palaiodimou, Aikaterini Theodorou, Maria Chondrogianni, Georgia Papagiannopoulou, Anna Keramida, Stella Fanouraki, Angeliki‐Erato Sterpi, Apostolos Safouris, Theodore Karapanayiotides, João Sargento‐Freitas, Claudio Baracchini, Branko Malojčić, Anastasios Bonakis, George P. Paraskevas, Andrei V. Alexandrov, Georgios Tsivgoulis   +16 more
wiley   +1 more source

Viscoelastic haemostatic assays in chronic liver disease—Profiling coagulation in the emergency department

Vox Sanguinis, Volume 121, Issue 3, Page 309-321, March 2026.
Abstract Background and Objectives The role of viscoelastic haemostatic assays (VHAs) versus conventional coagulation tests (CCTs) in chronic liver disease (CLD) in the emergency department (ED) is undefined. We aimed to characterize VHA profiles and concordance with CCT.
Akmez Latona, Kate Hill, Lara Roberts, Katherine Stuart, James Winearls, Biswadev Mitra   +5 more
wiley   +1 more source

Extended treatment for venous thromboembolism: Is direct oral anticoagulant dose‐reduction better for all?

HemaSphere, Volume 10, Issue 3, March 2026.
Mandy N. Lauw, Saskia Middeldorp, Marc Carrier   +2 more
wiley   +1 more source

Expression of Human Thrombomodulin Prevents Early Thrombocytopenia and Thrombotic Microangiopathy in Pig‐to‐Nonhuman Primate Orthotopic Liver Xenotransplantation

Xenotransplantation, Volume 33, Issue 2, March/April 2026.
Abstract Background Severe thrombocytopenia and coagulation dysregulation remain major barriers to survival in pig‐to‐primate liver xenotransplantation models. Methods Porcine livers with five genetic modifications (GTKO, CMAHKO, β4GalNT2KO, hCD55, and hTBM) were orthotopically transplanted into four Tibetan macaques under two conventional ...
Zhongqiang Zhang, Ting Li, Qiang Li, Bin Xie, Xinger Zhao, Jianbin Wang, Yaxun Huang, Jing Luo, Shali Wen, Yinchun Zhou, Yong Deng, Yanfang Lu, Yanyan Jiang, Jiequn Li, David K. C. Cooper, Dengke Pan, Zhongzhou Si, Haizhi Qi   +17 more
wiley   +1 more source

Papilledema due to Vaccine-Induced Thrombocytopenia. [PDF]

Ophthalmology, 2022
Qian J, Lutchman C, Margolin E.
europepmc   +1 more source

Insight into Residues Critical for Antithrombin Function from an Expanded Database of Sequences That Includes Frog, Turtle and Ostrich Antithrombins

The Scientific World Journal, 2002
Marija Backovic, Peter G.W. Gettins
doaj   +1 more source

Vascular endothelial cell: modern concepts of structure and function [PDF]

Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”, Chişinău, Republica MoldovaIntroducere. Celula endotelială vasculară rămâne până în prezent nestudiată pe deplin, descoperindu-se mereu noi funcții esențiale ale acestora în ...
Zavtoni, Anastasia
core  

Is Milk Thistle a Cardioprotective Ally or a Thrombotic Threat? [PDF]

JACC Case Rep
Lindner E, Alhmouz MM, Abuhalimeh R, Abuhalimeh L, Chin J, Qadura M, Younes H, Abuhalimeh BJ.   +7 more
europepmc   +1 more source

Acquired SERPINC1/antithrombin deficiency during oral contraceptive consumption: a case report. [PDF]

J Med Case Rep, 2023
Denora D, Di Rosa MV, Altamura N, Pellicori F, Vinci P, Sisto UG, Spanò F, Di Girolamo FG, Fiotti N, Biolo G.   +9 more
europepmc   +1 more source