Results 81 to 90 of about 1,433 (211)

P1 variant antithrombins Glasgow (393 Arg to His) and Pescara (393 Arg to Pro) have increased heparin affinity and are resistant to catalytic cleavage by elastase Implications for the heparin activation mechanism

, 1991
The heparin affinity of normal and two P1 variants of antithrombin-III (AT) was studied by gradient elution with NaCl in Tris buffer on heparin-Sepharose.
David A. Lane, Lane, David A., Peter M. George, Owen, Maurice C., Maurice C. Owen, George, Peter M., Boswell, D.Ross, D.Ross Boswell   +7 more
core   +1 more source

Multi‐Layered Genomic and Clinical Analysis Identifies Novel Variants, Co‐Occurring Single Nucleotide Polymorphism Pairs, and Clinical Determinants of Host‐Pathogen Interaction in COVID‐19 Severity

Journal of Medical Virology, Volume 98, Issue 6, June 2026.
ABSTRACT Host genetic factors may contribute to COVID‐19 severity. To identify genetic variants influencing COVID‐19 severity progression, whole‐exome sequencing was performed, followed by an exome‐wide association study on 191 hospitalized patients categorized into three severity groups.
Doris Repušić, Marina Korolija, Ana Livun, Tomo Svaguša, Robert Belužić, Vjekoslav Tomaić, Rosa Karlić, Kristian Vlahoviček   +7 more
wiley   +1 more source

Kommentar zu den Leitlinien 2010 zur kardiopulmonalen Reanimation des European Resuscitation Council

, 2010
Administer chest compressions (minimum 100/min, minimum 5 cm depth) at a ratio of 30:2 with ventilation (tidal volume 500-600 ml, inspiration time 1 s, F(I)O(2) if possible 1.0). Avoid any interruptions in chest compressions.
B.W. Böttiger, Boettiger, Bernd W., Wenzel, V., M.A. Baubin, M. Fries, U. Kreimeier, Baubin, M. A., Böttiger, B. W., J. Bahr, Eich, Christoph B., Fries, M., S.G. Russo, Russo, Sebastian Giuseppe, H.R. Arntz, Russo, S. G., Arntz, H. R., Kreimeier, U., Eich, C., B. Dirks, Bahr, Jan, V. Wenzel, C. Eich, Dirks, B., Bahr, J.   +23 more
core   +1 more source

Optimizing Venous Thromboembolism Prophylaxis in Burn Patients Using Enoxaparin Through PBPK Modeling

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 6, June 2026.
ABSTRACT Burn injuries cause physiological changes that alter enoxaparin pharmacokinetics, often leading to inadequate exposure and suboptimal venous thromboembolism (VTE) prophylaxis. Current weight‐based dosing and anti‐Xa monitoring provide limited guidance for dose optimization across burn severities.
Sabiha Rahman Mim, Venkata K. Yellepeddi, Francine J. Azeredo   +2 more
wiley   +1 more source

Antithrombins in Childhood Malnutrition

, 1979
G.I.C. Ingram, W. Vargas, R.A. Jiménez
core   +2 more sources

Estetrol‐based combined oral contraceptives: A systematic review of clinical outcomes

Acta Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 6, Page 983-998, June 2026.
This systematic review summarizes clinical outcomes of estetrol‐containing combined oral contraceptives, showing reliable contraceptive efficacy, predictable bleeding patterns, improved well‐being, and a favorable hemostatic and metabolic profile, suggesting a promising and potentially safer alternative to ethinylestradiol‐based formulations.
Mathilde Råberg, Ingeborg Rose Vad, Kara Hildur Axelsdóttir, Ellen Christine Leth Løkkegaard   +3 more
wiley   +1 more source

Successful use of haemoperfusion therapy in an adult horse with hepatic encephalopathy and cholangiohepatitis

Equine Veterinary Education, Volume 38, Issue 6, Page e307-e314, June 2026.
Summary A 4‐year‐old, 520 kg, American Quarter Horse broodmare, approximately 90 days in foal, was presented to Texas A&M University Teaching Hospital for suspected liver disease. Based on clinicopathological values and hepatic abnormalities noted ultrasonographically, the mare was presumptively diagnosed with cholangiohepatitis.
A. C. Trimble, S. H. White‐Springer, S. Alpini, E. Rumfola, A. N. DiSilvestro, Y. Ueda, K. Hobbs   +6 more
wiley   +1 more source

Clinical management and outcomes for 51 Pugs reportedly diagnosed with protein‐losing enteropathy using VetCompass primary care veterinary data

Journal of Small Animal Practice, Volume 67, Issue 6, Page 504-511, June 2026.
Objectives To report the clinicopathological findings, treatment and outcomes of Pugs diagnosed with protein‐losing enteropathy using VetCompass primary care clinical data in the UK and to determine if referral or any specific treatments for protein‐losing enteropathy were associated with outcome. Materials and Methods Retrospective VetCompass study of
A. Kathrani, D. C. Brodbelt, D. B. Church, D. G. O’Neill   +3 more
wiley   +1 more source

The time dependence of antithrombin initiation in patients with non-ST-segment elevation acute coronary syndromes: subgroup analysis from the ACUITY trial.

, 2011
STUDY OBJECTIVE: Antithrombins are among standard treatment agents for patients with non-ST-segment elevation acute coronary syndromes. We aimed to determine the association between time from emergency department (ED) presentation to treatment with an ...
Emerman, Charles L, Hoekstra, James W, Diercks, Deborah B, Rokos, Ivan C, Larson, David M, Blomkalns, Andra L, Hollander, Judd E, Mehran, Roxana, Pollack, Charles V, Stone, Gregg W   +9 more
core  

Direct antithrombins

, 2013
Vincenzo Toschi
core   +1 more source