Results 31 to 40 of about 1,671 (202)

A comparison of hirudin with heparin in the prevention of restenosis after coronary angioplasty [PDF]

, 1995
__Background:__ The likelihood of restenosis is a major limitation of coronary angioplasty. We studied whether hirudin, a highly selective inhibitor of thrombin with irreversible effects, would prevent restenosis after angioplasty.
Bode, C.H. (Christoph), Bos, A.A. (Arjan) van den, Close, P. (Philip), Deckers, J.W. (Jaap), Dijk, R. (Rene) van, Fox, K.A.A. (Keith), Herrman, J.P.R., Laarman, G-J. (GertJan), Rutsch, W.R. (Wolfgang), Serruys, P.W.J.C. (Patrick), Simon, R. (Rudiger), Umans, V.A.W.M. (Victor)   +11 more
core   +1 more source

O novo modelo da cascata de coagulação baseado nas superfícies celulares e suas implicações A cell-based model of coagulation and its implications

Revista Brasileira de Hematologia e Hemoterapia, 2010
O conceito da cascata da coagulação descreve as interações bioquímicas dos fatores da coagulação, entretanto, tem falhado como um modelo do processo hemostático in vivo. A hemostasia requer a formação de um tampão de plaquetas e fibrina no local da lesão
Cláudia Natália Ferreira, Marinez de Oliveira Sousa, Luci Maria Sant'Ana Dusse, Maria das Graças Carvalho   +3 more
doaj   +1 more source

Argatroban During Percutaneous Transluminal Coronary Angioplasty: Results of a Dose-Verification Study. [PDF]

, 1996
Background. Thrombin is a key enzyme in thrombogenesis. In animals, specific antithrombotic therapy at the time of coronary angioplasty reduced the incidence of subacute occlusion and inhibited the restenosis response.
Gabriel, L., Heijer, P. (Peter) den, Herrman, J.P.R., Kutryk, M.J.B. (Michael), Serruys, P.W.J.C. (Patrick), Suryapranata, H. (Harry)   +5 more
core   +1 more source

Efficacy and safety of direct oral anticoagulants compared with warfarin in antiphospholipid syndrome. Results of a multicenter retrospective cohort study

Research and Practice in Thrombosis and Haemostasis
Background: Direct oral anticoagulants (DOACs) have become firstline treatment for many thrombotic conditions, but their use in antiphospholipid syndrome (APS) patients remains controversial.
Maha A.T. Elsebaie, Zoe Wickham, Stephanie DeBragga, Stacey Fedewa, Mohamed Amgad, Jane Jungyoon Park, Allen Li, Ali Eshaghpour, Juan Li, Mark Crowther, Manila Gaddh   +10 more
doaj   +1 more source

Use of Antithrombin and Thrombomodulin in the Management of Disseminated Intravascular Coagulation in Patients with Acute Cholangitis

Gut and Liver, 2013
Background/AimsTo evaluate the usefulness and safety of treating disseminated intravascular coagulation (DIC) complicating cholangitis primarily with antithrombin (AT) and thrombomodulin (rTM).Methods : A DIC treatment algorithm was determined on the ...
doaj   +1 more source

Lifetime cardiovascular management of patients with previous Kawasaki disease. [PDF]

, 2020
Kawasaki disease (KD) is an inflammatory disorder of young children, associated with vasculitis of the coronary arteries with subsequent aneurysm formation in up to one-third of untreated patients.
Brogan, Paul, Burns, Jane C, Cornish, Jacqueline, Diwakar, Vinod, Eleftheriou, Despina, Gordon, John B, Gray, Huon Hamilton, Johnson, Thomas William, Kawasaki Disease Writing Group, on behalf of the Royal College of Paediatrics and Child Health, and the British Cardiovascular Society, Levin, Michael, MacCarthy, Philip, Malik, Iqbal, McCormack, Rachael, Miller, Owen, Tulloh, Robert MR   +14 more
core   +1 more source

A Novel Serpin with Antithrombin-Like Activity in Branchiostoma japonicum: Implications for the Presence of a Primitive Coagulation System [PDF]

, 2012
Serine protease inhibitors, or serpins, are a group of widely distributed proteins with similar structures that use conformational change to inhibit proteases.
Chao, Yeqing, Fan, Chunxin, Gao, Bei, Liang, Yujun, Zhang, Shicui   +4 more
core   +5 more sources

Real world experience reflecting current guidelines [PDF]

, 2020
Background: In case of suspected acute coronary syndrome (ACS), international guidelines recommend to obtain a 12-lead ECG as soon as possible after first medical contact, to administrate platelet aggregation inhibitors and antithrombins, and to transfer
Drexler, Berthold, Eckle, Veit-Simon, Lehmann, S.   +2 more
core   +1 more source

Mechanistic behaviour and molecular interactions of heat shock protein 47 (HSP47) [PDF]

, 2012
This project involves the study of heat shock protein 47 (HSP47), which is a molecular chaperone crucial for collagen biosynthesis. It exhibits a high degree of sequence homology with members of the serine protease inhibitor (serpin) superfamily, though ...
Abdul Wahab, Mohd Firdaus, Abdul Wahab, Mohd Firdaus   +1 more
core   +1 more source

Informetrics on accidents and trauma [PDF]

, 1998
MEDLINE database has been analysed for 1995-97 on index Accidents and Trauma. Publications output has been classified year-wise country-wise, journal-wise and other fine structure characteristics have been found.
Kadam, S. N., Kalyane, V. L.
core