Results 11 to 20 of about 42,772 (209)

Mortality and Associated Factors Among Adult Tetanus Patients Admitted at Public Hospitals in Bahir Dar City, Ethiopia: A Cross-Sectional Study. [PDF]

open access: yesHealth Sci Rep
ABSTRACT Background and Aims Tetanus, caused by Clostridium tetani, results in rigor spasms and remains as major cause of mortality in areas with poor vaccination and sanitation. Mortality has been cited to be 20%–55% in Ethiopia, possibly due to variation in healthcare, immunization, and intensive care access.
Tesfaw M   +3 more
europepmc   +2 more sources

Two VHH Antibodies Neutralize Botulinum Neurotoxin E1 by Blocking Its Membrane Translocation in Host Cells

open access: yesToxins, 2020
Botulinum neurotoxin serotype E (BoNT/E) is one of the major causes of human botulism, which is a life-threatening disease caused by flaccid paralysis of muscles. After receptor-mediated toxin internalization into motor neurons, the translocation domain (
Kwok-Ho Lam   +3 more
doaj   +1 more source

Production, Characterisation and Testing of an Ovine Antitoxin against Ricin; Efficacy, Potency and Mechanisms of Action

open access: yesToxins, 2017
Ricin is a type II ribosome-inactivating toxin that catalytically inactivates ribosomes ultimately leading to cell death. The toxicity of ricin along with the prevalence of castor beans (its natural source) has led to its increased notoriety and ...
Sarah J. C. Whitfield   +8 more
doaj   +1 more source

Investigation of the Frequency of Foodborne Botulism in Patients Referred to Loghman Hospital in Tehran City, Iran, From 2008 to 2019 [PDF]

open access: yesInternational Journal of Medical Toxicology and Forensic Medicine, 2020
Background: Foodborne botulism is a fatal paralytic illness caused mainly by the neurotoxin produced by an anaerobic bacterium called Clostridium botulinum. In this study, the frequency of foodborne botulism in patients referred to a hospital in Iran has
Mohammad Mehdi Soltan Dallal   +7 more
doaj   +1 more source

A case of asymmetric cranial nerve palsy due to iatrogenic botulism [PDF]

open access: yesAsia Pacific Journal of Medical Toxicology, 2021
Introduction:Botulism is a rare but lethal disease and atypical clinical presentations of this disease are difficult to diagnose. We report a case of iatrogenic botulism who presented withasymmetric cranial nerve involvement.Case report:An eighteen year ...
Muhammad Akbar Baig, Joshua Nogar
doaj   +1 more source

Medical Countermeasures against Ricin Intoxication

open access: yesToxins, 2023
Ricin toxin is a disulfide-linked glycoprotein (AB toxin) comprising one enzymatic A chain (RTA) and one cell-binding B chain (RTB) contained in the castor bean, a Ricinus species.
Christine Rasetti-Escargueil   +1 more
doaj   +1 more source

YoeB toxin is activated during thermal stress. [PDF]

open access: yes, 2015
Type II toxin-antitoxin (TA) modules are thought to mediate stress-responses by temporarily suppressing protein synthesis while cells redirect transcription to adapt to environmental change.
Garza-Sánchez, Fernando   +2 more
core   +1 more source

Toxin-Antitoxin Systems: A Key Role on Persister Formation in Salmonella enterica Serovar Typhimurium

open access: yesInfection and Drug Resistance, 2022
Made Rai Dwitya Wiradiputra,1,2 Piyatip Khuntayaporn,1,3 Krit Thirapanmethee,1,3 Mullika Traidej Chomnawang1,3 1Antimicrobial Resistance Interdisciplinary Group (AmRIG), Faculty of Pharmacy, Mahidol University, Bangkok, Thailand; 2Biopharmaceutical ...
Wiradiputra MRD   +3 more
doaj  

The role of small proteins in Burkholderia cenocepacia J2315 biofilm formation, persistence and intracellular growth [PDF]

open access: yes, 2019
Burkholderia cenocepacia infections are difficult to treat due to resistance, biofilm formation and persistence. B. cenocepacia strain J2315 has a large multi-replicon genome (8.06 Mb) and the function of a large fraction of (conserved) hypothetical ...
Braeckmans, Kevin   +12 more
core   +1 more source

The bacterial antitoxin HipB establishes a ternary complex with operator DNA and phosphorylated toxin HipA to regulate bacterial persistence [PDF]

open access: yes, 2014
Nearly all bacteria exhibit a type of phenotypic growth described as persistence that is thought to underlie antibiotic tolerance and recalcitrant chronic infections.
Behiels, Ester   +6 more
core   +2 more sources

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