Results 81 to 90 of about 59,908 (306)
Proteins: Structure, Function, and Bioinformatics, EarlyView.ABSTRACT The HADDOCK team participated in CAPRI rounds 47–55 as server, manual predictor, and scorers. Throughout these CAPRI rounds, we used a plethora of computational strategies to predict the structure of protein complexes. Of the 10 targets comprising 24 interfaces, we achieved acceptable or better models for 3 targets in the human category and 1 ...
Victor Reys +16 more
wiley +1 more source
Recurrent diphtheria outbreaks in Nigeria: A review of the underlying factors and remedies
Immunity, Inflammation and Disease, 2023 Introduction The introduction of the diphtheria−tetanus−pertussis (DTP) vaccine into childhood immunization programs resulted in its widespread elimination in high‐income countries. However, Nigeria is currently experiencing an outbreak.
Nasir Abdulrasheed +10 more
doaj +1 more source
mBio, 2018 Persistence is a reversible and low-frequency phenomenon allowing a subpopulation of a clonal bacterial population to survive antibiotic treatments. Upon removal of the antibiotic, persister cells resume growth and give rise to viable progeny.
F. Goormaghtigh +11 more
semanticscholar +1 more source
Biomolecular Interaction Prediction in the Pre‐ and Post‐AlphaFold Era: The 8th CAPRI Evaluation
Proteins: Structure, Function, and Bioinformatics, EarlyView.ABSTRACT We report on the 8th CAPRI Evaluation period, capturing the assessment of CAPRI Rounds 47 to 55 (excluding the CASP and COVID‐related Rounds), which have witnessed the transition to AI‐driven prediction tools such as AlphaFold and related alternatives. The prediction Rounds in this evaluation are characterized by a high level of difficulty due
Marc F. Lensink +5 more
wiley +1 more source
Identification and characterisation of toxin-antitoxin systems (TA) in Burkholderia pseudomallei [PDF]
, 2013 The aim of this study was to identify and characterise type II toxin-antitoxin (TA) systems in Burkholderia pseudomallei, the causative agent of the human disease melioidosis. 8 putative TA systems were identified within the genome of B. pseudomallei
Butt, Aaron Trevor
core
The mazEF toxin-antitoxin system as a novel antibacterial target in Acinetobacter baumannii [PDF]
, 2014 Although analysis of toxin-antitoxin (TA) systems can be instructive, to date, there is no information on the prevalence and identity of TA systems based on a large panel of Acinetobacter baumannii clinical isolates.
Ghafourian, S +6 more
core +5 more sources
Proteins: Structure, Function, and Bioinformatics, EarlyView.ABSTRACT We present the methods and results of our protein complex and RNA structure predictions at CASP16. Our approach integrated multiple state‐of‐the‐art deep learning models with a consensus‐based scoring method. To enhance the depth of multiple sequence alignments (MSAs), we employed a large metagenomic sequence database.
Yuki Kagaya +10 more
wiley +1 more source
A Rabbit Model for the Evaluation of Drugs for Treating the Chronic Phase of Botulism
Toxins, 2021 Antitoxin, the only licensed drug therapy for botulism, neutralizes circulating botulinum neurotoxin (BoNT). However, antitoxin is no longer effective when a critical amount of BoNT has already entered its target nerve cells.
Amram Torgeman +6 more
doaj +1 more source
Cluster of Botulism among dutch tourists in Turkey, june 2008 [PDF]
, 2010 In June 2008, three Dutch tourists participating in a mini-cruise in Turkey needed urgent repatriation for antitoxin treatment because of symptoms of botulism.
Ouwerkerk, M., van +2 more
core +1 more source
TASmania: A bacterial Toxin-Antitoxin Systems database
PLoS Comput. Biol., 2019 Bacterial Toxin-Antitoxin systems (TAS) are involved in key biological functions including plasmid maintenance, defense against phages, persistence and virulence.
H. Akarsu +5 more
semanticscholar +1 more source