Results 91 to 100 of about 9,583 (206)
Equine Veterinary Journal, EarlyView.Abstract Botulism is a severe and often fatal disease in equine patients worldwide. Clostridium botulinum is a ubiquitous soil organism which produces a potent neurotoxin resulting in neuromuscular blockade and flaccid paralysis in affected animals. Definitive diagnosis is often impractical or impossible, leading to diagnosis and treatment based on ...
Kali Slavik +2 more
wiley +1 more source
Toxins, 2018 The presence of botulinum neurotoxin-producing Clostridia (BPC) in food sources is a public health concern. In favorable environmental conditions, BPC can produce botulinum neurotoxins (BoNTs) outside or inside the vertebrate host, leading to ...
Luca Bano +7 more
doaj +1 more source
The FEBS Journal, EarlyView.When overexpressed in Staphylococcus aureus, the type I toxins SprA1 and SprA2 form membrane pores, with SprA1 creating stable pores and SprA2 forming transient ones. Both induce concomitant membrane depolarization, ATP release, and growth arrest, while only SprA1 causes membrane permeabilization due to its stable pore formation.
Laurence Fermon +10 more
wiley +1 more source
Antitoxin as a Prophylactic [PDF]
The Boston Medical and Surgical Journal, 1897 n ...
openaire +3 more sources
Molecular Microbiology, EarlyView.Using bioinformatic tools, we identified a diverse defensome in Actinobacillus pleuropneumoniae, featuring various defense mechanisms. Genomes show co‐occurring systems like CRISPR, Abi, and restriction‐modification (RM) systems, underscoring the complexity and dynamic nature of their defensome cargo.
Giarlã Cunha da Silva +1 more
wiley +1 more source
Development of an Innovative in Vitro Potency Assay for Anti-Botulinum Antitoxins
Toxins, 2016 Botulinum neurotoxins are bacterial proteins that cause botulism, a life-threatening disease. Therapy relies mostly on post-intoxication antibody treatment. The only accepted method to measure the potency of, and to approve, antitoxin preparations is the
Osnat Rosen +4 more
doaj +1 more source
Medical and Veterinary Entomology, EarlyView.The fitness of Anopheles coluzzii mosquito lines (VK strain) selected for early and late egg hatching was compared with each other and a reference strain (Mopti). There was an observed increase in fitness in fecundity and survival among the late‐hatching lines, but no negative effects of selection on fecundity and adult survival were detected.
Emmanuel C. Ottih +3 more
wiley +1 more source
The bacterial Type III toxin-antitoxin system, ToxIN, is a dynamic protein-RNA complex with stability-dependent antiviral abortive infection activity. [PDF]
, 2018 Bacteria have evolved numerous defense systems to protect themselves from viral (bacteriophage) infection. The ToxIN system of Pectobacterium atrosepticum is a Type III toxin-antitoxin complex and "altruistic suicide" anti-phage system, which kills phage-
Akusobi, Chidiebere +3 more
core +2 more sources