Results 81 to 90 of about 26,184 (286)
PLoS ONE, 2011 The chromosome of Mycobacterium tuberculosis (Mtb) encodes forty seven toxin-antitoxin modules belonging to the VapBC family. The role of these modules in the physiology of Mtb and the function(s) served by their expansion are unknown.
B. Ahidjo +7 more
semanticscholar +1 more source
Dysphagia in an equine referral hospital, 182 cases
Equine Veterinary Journal, EarlyView.Abstract Background Dysphagia describes a clinical sign of pathologies of the oral cavity, pharynx, and oesophagus that carries potentially serious consequences for horses. Given the diversity of differential diagnoses that may cause dysphagia, an understanding of the prevalence of dysphagia in hospitalised patients, the distribution of aetiologies and
Kevin M. Connolly, Krista Estell
wiley +1 more source
The FEBS Journal, EarlyView.When overexpressed in Staphylococcus aureus, the type I toxins SprA1 and SprA2 form membrane pores, with SprA1 creating stable pores and SprA2 forming transient ones. Both induce concomitant membrane depolarization, ATP release, and growth arrest, while only SprA1 causes membrane permeabilization due to its stable pore formation.
Laurence Fermon +10 more
wiley +1 more source
Molecular Microbiology, EarlyView.Using bioinformatic tools, we identified a diverse defensome in Actinobacillus pleuropneumoniae, featuring various defense mechanisms. Genomes show co‐occurring systems like CRISPR, Abi, and restriction‐modification (RM) systems, underscoring the complexity and dynamic nature of their defensome cargo.
Giarlã Cunha da Silva +1 more
wiley +1 more source
Multiple Toxin-Antitoxin Systems in Mycobacterium tuberculosis
Toxins, 2014 The hallmark of Mycobacterium tuberculosis is its ability to persist for a long-term in host granulomas, in a non-replicating and drug-tolerant state, and later awaken to cause disease.
Ambre Sala +2 more
doaj +1 more source
Control of Toxin-Antitoxin Systems by Proteases in Mycobacterium Tuberculosis
Frontiers in Molecular Biosciences, 2021 Toxin-antitoxin (TA) systems are small genetic elements composed of a noxious toxin and a counteracting cognate antitoxin. Although they are widespread in bacterial chromosomes and in mobile genetic elements, their cellular functions and activation ...
Patricia Bordes, Pierre Genevaux
doaj +1 more source
Vesiculation as potential novel pathogenic mechanism in autoimmune hemolytic anemia
Transfusion, EarlyView.Abstract Background Autoimmune hemolytic anemia (AIHA) is typically mediated by immunoglobulin G (IgG) or immunoglobulin M (IgM) antibodies, and more rarely by immunoglobulin A (IgA). The mechanism of red blood cell (RBC) destruction in IgA‐mediated AIHA is not well understood.
Esther C. W. de Boer +14 more
wiley +1 more source
Toxins, Pathogenicity, Anti-Toxins, a Bicentennial Contribution
ToxinsThe bicentenary of Louis Pasteur’s birth raises the opportunity to revisit the activity and influence of L [...]
Michel R. Popoff, Daniel Ladant
doaj +1 more source