Results 141 to 150 of about 2,263 (168)

Antimicrobial, antitrypanosomal and antibiofilm activity of Equisetum hyemale

Microbial Pathogenesis, 2016
This study evaluates, for the first time, the antibiofilm, antimicrobial and antiparasitic potential of crude extract and fractions of stems of Equisetum hyemale against several infectious agents (bacteria, fungi, Mycobacterium and Trypanosomes) by broth microdilution technique and investigates the phenolic composition of the plant by high performance ...
Camilla Filippi dos Santos Alves, Pauline Cordenonsi Bonez, Marcia de Ebling de Souza, Ritiel Corrêa da Cruz, Aline Augusti Boligon, Mariana Piana, Thiele Facim Brum, Grazielle Guidolin Rossi, Roberta da Silva Jesus, Thirssa Helena Grando, Silvia Gonzalez Monteiro, Marli Matiko Anraku de Campos, Janice Luering Giongo, Roberto Christ Vianna Santos   +13 more
openaire   +2 more sources

Antileishmanial and Antitrypanosomal Activities of Flavonoids

2018
This chapter focuses on the ability of flavonoid aglycones and glycosides to inhibit the growth of protozoan parasites of the genera Leishmania and Trypanosoma in different in vitro and in vivo models, namely pathogenic species for humans implicated in visceral (L. donovani, L. infantum) and cutaneous leishmaniasis (L. braziliensis, L.
Flore Nardella, Jean-Baptiste Gallé, Mélanie Bourjot, Bernard Weniger, Catherine Vonthron-Sénécheau   +4 more
openaire   +1 more source

In vitro evaluation of antitrypanosomal activity and molecular docking of benzoylthioureas

Parasitology International, 2021
A series of sixteen benzoylthioureas derivatives were initially evaluated in vitro against the epimastigote form of Trypanosoma cruzi. All of the tested compounds inhibited the growth of this form of the parasite, and due to the promising anti-epimastigote activity from three of these compounds, they were also assayed against the trypomastigote and ...
Patricia M L, Pereira, Priscila G, Camargo, Bruna T, Fernandes, Luiz A P, Flores-Junior, Luiza R S, Dias, Camilo H S, Lima, Phileno, Pinge-Filho, Lucy M Y, Lioni, Sueli F, Yamada-Ogatta, Marcelle L F, Bispo, Fernando, Macedo   +10 more
openaire   +2 more sources

Synthesis and in vitro antitrypanosomal activity of novel Nifurtimox analogues

Bioorganic & Medicinal Chemistry Letters, 2005
AbstractFor Abstract see ChemInform Abstract in Full Text.
Rocío, Pozas, Javier, Carballo, Clementina, Castro, Julieta, Rubio   +3 more
openaire   +2 more sources

Antiplasmodial and antitrypanosomal activity of Triclisia sacleuxii (Pierre) Diels

Phytomedicine, 2008
The antiplasmodial and antitrypanosomal activities of Triclisia sacleuxii (Pierre) Diels were investigated on three Plasmodium falciparum strains [FcB1, 3D7 (chloroquine-sensitive) and W2 (chloroquine-resistant) strains] and on Trypanosoma brucei Tbsf 221.
Murebwayire, Sangabo, Frederich, Michel, Hannaert, V., Jonville, Marie, Duez, Pierre   +4 more
openaire   +4 more sources

In vitro antitrypanosomal activity ofMoringa stenopetala leaves and roots

Phytotherapy Research, 1999
The leaves and the root extracts of Moringa stenopetala were tested in vitro against trypomastigotes of Trypanosoma brucei, Trypanosoma cruzi and L. donovani amastigotes. The fresh root wood ethanol extract and the dried leaves acetone extract were found to be active against T.
Y, Mekonnen, V, Yardley, P, Rock, S, Croft   +3 more
openaire   +2 more sources

Antitrypanosomal activities and cytotoxicity of 5-nitro-2-furancarbohydrazides

Bioorganic & Medicinal Chemistry Letters, 2002
AbstractFor Abstract see ChemInform Abstract in Full Text.
Régis, Millet, Louis, Maes, Valérie, Landry, Christian, Sergheraert, Elisabeth, Davioud-Charvet   +4 more
openaire   +2 more sources

Antitrypanosomal Activity of Trivalent Antimonials in vitro and Its Significance

Chemotherapy, 2009
The Sb_III preparations available for clinical use were compared in vitro for their concentration/time/effect curves on Trypanosoma venezuelense (T. evansi), measuring decrease of motility and of parasite numbers. With these two criteria leading to similar relative results, the drugs are classified into a rapidly acting group, led
Ercoli N., BERTAZZONI MINELLI, Elisa, Olivo N.   +2 more
openaire   +3 more sources

5'-Chloropuromycin. Inhibition of protein synthesis and antitrypanosomal activity

Journal of Medicinal Chemistry, 1981
A facile, two-step conversion of puromycin aminonucleoside (PAN) into 5'-deoxy-PAN (5) via 5'-chloro-5'-deoxy-PAN (1) was accomplished. Replacement of the 5'-OH group of PAN with H or Cl resulted in the elimination of kidney toxicity associated with the administration of PAN.
R, Vince, H, Lee, A S, Narang, F N, Shirota   +3 more
openaire   +2 more sources

Chagas' disease: carcinogenic activity of the antitrypanosomal nitroarenes in mice

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 1994
The carcinogenic activity of antitrypanosomal 2-nitroimidazole, 5-nitroimidazole and 5-nitrofuran derivatives was assessed in female Swiss mice of the same age group. A statistically significantly higher incidence of growths was seen in mice into which 2-nitro had been injected than in mice receiving 5-nitro derivatives intraperitoneally.
A R, Teixeira, M A, Calixto, M L, Teixeira   +2 more
openaire   +2 more sources