Results 201 to 210 of about 25,061 (213)
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Mycothiol: A promising antitubercular target
Bioorganic Chemistry, 2014Tuberculosis (TB) is the world's second commonest cause of death next to HIV/AIDS. The increasing emergence of multi drug resistance and the recalcitrant nature of persistent infections pose an additional challenge for the treatment of TB. Due to the development of resistance to conventional antibiotics there is a need for new therapeutic strategies to
Muthu K. Kathiravan, Shrikant Nilewar
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ChemInform Abstract: Quinazoline Derivatives with Antitubercular Activity.
ChemInform, 2000AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Karel Waisser +5 more
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Antitubercular diterpenoids from Vitex trifolia
Phytomedicine, 2013A new halimane diterpenoid, 13-hydroxy-5(10),14-halimadien-6-one (1) and two new labdane diterpenoids, 6α,7α-diacetoxy-13-hydroxy-8(9),14-labdadien (2) and 9-hydroxy-13(14)-labden-15,16-olide (3), were isolated for the first time, along with fifteen known compounds, from the hexane soluble fraction of methanolic extract of Vitex trifolia leaves.
Madan M. Gupta +3 more
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Antitubercular Constituents ofValeriana laxiflora
Planta Medica, 2004Antitubercular bioassay-guided fractionation of the n-hexane- and CH (2)Cl (2)-soluble extracts of the above-ground biomass and roots of Valeriana laxiflora led to the isolation of a new iridolactone, (4R,5R,7S,8S,9S)-7-hydroxy-8-hydroxymethyl-4-methyl-perhydrocyclopenta[ c]pyran-1-one ( 1), and a new lignan, (+)-1-hydroxy-2,6-bis- epi-pinoresinol ( 2),
Gu J.Q. +5 more
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Salicylhydroxamic Acid as an Antitubercular Agent
Nature, 1950SOME derivatives of salicylic acid possess antitubercular properties, the most important of such substances being the well-known p-aminosalicylic acid used by Lehmann1. Nevertheless, numerous investigations seem to indicate that most of the antitubercular compounds contain amino-groups.
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Recent Developments in Antitubercular Drugs
Mini-Reviews in Medicinal Chemistry, 2008This review article describes the current TB drugs, their merits and demerits as well as the new promising anti-TB agents such as diarylquinolines, oxazolidinones and nitroimdiazoles. It also includes the future development of new antitubercular agents according to the potential drug targets of Mycobacterium tuberculosis and structure-activity ...
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Synthetic antitubercular preparations
Pharmaceutical Chemistry Journal, 1970openaire +2 more sources