Results 211 to 220 of about 35,652 (265)

Pregnancy outcomes after all modes of conception in patients with genital tuberculosis: a systematic review and meta-analysis. [PDF]

Obstet Gynecol Sci
Tjahjadi D, Aviani JK, Tjandraprawira KD, Parwati I, Permadi W, Djuwantono T, Li TC.   +6 more
europepmc   +1 more source

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QcrB in Mycobacterium tuberculosis: The new drug target of antitubercular agents

Medicinal research reviews (Print), 2021
Drug‐resistance in mycobacterial infections is a major global health problem that leads to high mortality and socioeconomic pressure in developing countries around the world.
A. Bahuguna, Srishti Rawat, D. Rawat
semanticscholar   +1 more source

Dumulmycin, an Antitubercular Bicyclic Macrolide from a Riverine Sediment-Derived Streptomyces sp.

Organic Letters, 2021
Dumulmycin (1) was isolated from Streptomyces sp. DM28, a bacterial strain from a riverine sediment sample. The structure of 1 was elucidated as a bicyclic macrolide possessing 19-membered and 5-membered rings by spectroscopic analysis.
Joon Soo An, B. Shin, Tae Ho Kim, Sunghoon Hwang, Yern-Hyerk Shin, Jinsheng Cui, Young Eun Du, Jung Yi, S. Nam, Suckchang Hong, Jongheon Shin, Jichan Jang, Y. Yoon, D. Oh   +13 more
semanticscholar   +1 more source

Altered expressions of circulating microRNAs 122 and 192 during antitubercular drug induced liver injury indicating their role as potential biomarkers

Human and Experimental Toxicology, 2021
Drug induced liver toxicity is a serious health complication leading to high mortality rates and post marketing withdrawal of drugs. Although considered to be the gold standard biomarkers; aspartate aminotransferase, alanine aminotransferase, total ...
S. Bakshi, M. Kaur, N. Saini, A. Mir, A. Duseja, S. Sinha, S. Sharma   +6 more
semanticscholar   +1 more source

Identification of novel multitarget antitubercular inhibitors against mycobacterial peptidoglycan biosynthetic Mur enzymes by structure-based virtual screening

Journal of Biomolecular Structure and Dynamics, 2021
Current therapeutic strategies for several diseases, including Mycobacterium tuberculosis infection, have evolved from an initial single-target treatment to a multitarget one.
Madhulata Kumari, N. Subbarao
semanticscholar   +1 more source

An overview of new antitubercular drugs, drug candidates, and their targets

Medicinal research reviews (Print), 2020
The causative agent of tuberculosis (TB), Mycobacterium tuberculosis and more recently totally drug‐resistant strains of M. tuberculosis, display unique mechanisms to survive in the host.
A. Bahuguna, D. Rawat
semanticscholar   +1 more source

Antitubercular Activity of New Coumarins [PDF]

Chemical Biology & Drug Design, 2011
The present article describes a series of 21 N ′‐benzylidene‐2‐oxo‐2H‐chromene‐3‐carbohydrazides 4a–4v, which were synthesized and evaluated for their cell viabilities in non‐infected and Mycobacterium bovis Bacillus Calmette–Guerin‐infected macrophages.
Milena Barbosa Barreto, André L. P. Candéa, Maria das Graças M. O. Henriques, Maria C.S. Lourenço, Carlos R. Kaiser, Marcus V. N. de Souza, Sílvia Helena Cardoso   +6 more
openaire   +2 more sources

Antitubercular Action of Disinfectants

Journal of Applied Bacteriology, 1971
SUMMARY: The antitubercular effect of disinfectants has been tested with adaptations of 2 recently introduced techniques (Kelsey & Sykes, 1969; Bergan & Lystad, 1971b). Only the phenolic compounds tested were effective tuberculocides.
T. Bergan, A. Lystad
openaire   +2 more sources

Pyrazole-coumarin and pyrazole-quinoline chalcones as potential antitubercular agents.

Archiv der Pharmazie, 2020
Pyrazole, coumarin, and quinoline are medicinally important moieties. In this study, two series of novel pyrazole-coumarin chalcones and pyrazole-quinoline chalcones were synthesized using multiple-step reactions.
Gautam Kumar, Vagolu Siva Krishna, D. Sriram, S. Jachak   +3 more
semanticscholar   +1 more source