Synthesis, Characterization, and Biological Evaluation of New Derivatives Targeting MbtI as Antitubercular Agents [PDF]
Pharmaceuticals, 2021 Tuberculosis (TB) causes millions of deaths every year, ranking as one of the most dangerous infectious diseases worldwide. Because several pathogenic strains of Mycobacterium tuberculosis (Mtb) have developed resistance against most of the established ...
Matteo Mori +8 more
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Exploration of Piperidinols as Potential Antitubercular Agents [PDF]
Molecules, 2014 Novel drugs to treat tuberculosis are required and the identification of potential targets is important. Piperidinols have been identified as potential antimycobacterial agents (MIC < 5 μg/mL), which also inhibit mycobacterial arylamine N ...
Areej Abuhammad +6 more
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Dataset of 2-(2-(4-aryloxybenzylidene) hydrazinyl) benzothiazole derivatives for GQSAR of antitubercular agents [PDF]
Data in Brief, 2017 Fragment based Quantitative structure activity relationship (QSAR) analysis on reported 25 2-(2-(4-aryloxybenzylidene) hydrazinyl) benzothiazole dataset as antitubercular agents were carried out.
Amit S. Tapkir +2 more
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Cinnamic Derivatives as Antitubercular Agents: Characterization by Quantitative Structure–Activity Relationship Studies [PDF]
Molecules, 2020 Tuberculosis, caused by Mycobacterium tuberculosis (Mtb), remains one of the top ten causes of death worldwide and the main cause of mortality from a single infectious agent.
Cátia Teixeira +4 more
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Phytogenic silver, gold, and bimetallic nanoparticles as novel antitubercular agents [PDF]
International Journal of Nanomedicine, 2016 Richa Singh,1 Laxman Nawale,2 Manisha Arkile,2 Sweety Wadhwani,1 Utkarsha Shedbalkar,1 Snehal Chopade,1 Dhiman Sarkar,2 Balu Ananda Chopade1,3 1Department of Microbiology, Savitribai Phule Pune University, 2Combichem-Bioresource Center, Organic ...
Singh R +7 more
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Synthesis, in-vitro antitubercular, antifungal activities and in silico molecular docking study of Chalcone derivatives from 1-(2'-Hydroxyphenyl)-3-(substituted-phenyl)-2-propenone. [PDF]
Microbes and Infectious Diseases, 2023 Background: Tuberculosis (TB) is one of the major global health problems and faced to the increased resistance of Mycobacterium tuberculosis strains against existing antitubercular agents, it is important to look for new antitubercular drugs.
Arnold Mulula +4 more
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Journal of Dr. NTR University of Health Sciences, 2021 Anti-tubercular therapy (ATT) drugs are the mainstay of management of tuberculosis worldwide. These medicines are used extensively across the globe in treating tubercular infections of any organ.
Simarjit S Rehsi +6 more
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Isoniazid associated psychosis: case series from a tertiary care centre
Open Journal of Psychiatry and Allied Sciences, 2018 Isoniazid (INH) is a commonly used first line antitubercular drug. INH associated psychosis is a rare psychiatric manifestation. We report two cases of pulmonary tuberculosis, where the patients developed psychosis after being given a therapeutic dose of
Hemendra Singh +3 more
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Clinically Relevant Interactions between Atypical Antipsychotics and Anti-Infective Agents
Pharmaceuticals, 2020 This is a comprehensive review of the literature on drug interactions (DIs) between atypical antipsychotics and anti-infective agents that focuses on those DIs with the potential to be clinically relevant and classifies them as pharmacokinetic (PK) or ...
Edoardo Spina +3 more
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Pathogens, 2018 Mycobacterium tuberculosis is the causative agent of tuberculosis, an ancient disease which, still today, represents a major threat for the world population. Despite the advances in medicine and the development of effective antitubercular drugs, the cure
Davide M. Ferraris +3 more
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