Attenuation of Mycobacterium species through direct and macrophage mediated pathway by unsymmetrical diaryl urea [PDF]
, 2016 Tuberculosis is a major threat for mankind and the emergence of resistance strain of Mycobacterium tuberculosis (Mtb) against first line antibiotics makes it lethal for human civilization.
Charan Raja, Mamilla R. +10 more
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Molecules, 2020 Infectious diseases caused by fungi and mycobacteria pose an important problem for humankind. Similarly, cancer is one of the leading causes of death globally.
Afzal B. Shaik +6 more
doaj +1 more source
The challenge of managing extensively drug-resistant tuberculosis at a referral hospital in the state of São Paulo, Brazil: a report of three cases [PDF]
Jornal Brasileiro de Pneumologia, 2015 Here, we report the cases of three patients diagnosed with extensively drug-resistant tuberculosis and admitted to a referral hospital in the state of São Paulo, Brazil, showing the clinical and radiological evolution, as well as laboratory test results,
Marcos Abdo Arbex +3 more
doaj +3 more sources
Analgesic Activity of Some 1,2,4-Triazole Heterocycles Clubbed with Pyrazole, Tetrazole, Isoxazole and Pyrimidine [PDF]
, 2013 Purpose: In the present study in vivo analgesic activity of some previously synthesized 1,2,4-triazole derivatives containing pyrazole, tetrazole, isoxazole and pyrimidine ring have been evaluated.
Appala Raju +3 more
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Chemistry Central Journal, 2018 Background The study describes the synthesis, characterization, in vitro antimicrobial and anticancer evaluation of a series of 2-(1-benzoyl-1H-benzo[d]imidazol-2-ylthio)-N-substituted acetamide derivatives. The synthesized derivatives were also assessed
Snehlata Yadav +6 more
doaj +1 more source
Colo‐appendico‐duodenal fistula: Rare presentation of extrapulmonary tuberculosis
Clinical Case Reports, 2021 A colo‐appendico‐duodenal fistula is a rare occurrence that results from extrapulmonary tuberculosis (TB) complications, especially in the endemic region.
David Eng Yeow Gan +3 more
doaj +1 more source
Development of Pseudomembranous Colitis Four Months after Initiation of Rifampicin
Case Reports in Gastroenterology, 2011 Pseudomembranous colitis (PMC) may develop with long-term antibiotic administration, but is rarely reported to be caused by antitubercular agents. We present a case of PMC that occurred 120 days after starting rifampicin.
Jeong Moon Choi +4 more
doaj +1 more source
Synthesis and Evaluation of the 2-Aminothiazoles as Anti-Tubercular Agents. [PDF]
PLoS ONE, 2016 The 2-aminothiazole series has anti-bacterial activity against the important global pathogen Mycobacterium tuberculosis. We explored the nature of the activity by designing and synthesizing a large number of analogs and testing these for activity against
Edward A Kesicki +12 more
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Antitubercular drugs for an old target: GSK693 as a promising InhA direct inhibitor [PDF]
, 2016 Despite being one of the first antitubercular agents identified, isoniazid (INH) is still the most prescribed drug for prophylaxis and tuberculosis (TB) treatment and, together with rifampicin, the pillars of current chemotherapy.
Martínez-Hoyos, María +29 more
core +3 more sources
Ursolic and oleanolic acids as antimicrobial and immunomodulatory compounds for tuberculosis treatment [PDF]
, 2013 BACKGROUND: New alternatives for the treatment of Tuberculosis (TB) are urgently needed and medicinal plants represent a potential option. Chamaedora tepejilote and Lantana hispida are medicinal plants from Mexico and their hexanic extracts have shown ...
Adelina Jiménez-Arellanes +9 more
core +1 more source