Results 81 to 90 of about 54,172 (172)

Some Biological Applications and Mechanistic Insights of Benzaldehyde‐Substituted Thiosemicarbazones and Their Metal Complexes: A Review

open access: yesNatural Sciences, EarlyView.
ABSTRACT Thiosemicarbazones (TSCs) and their metal complexes have been subjected to study over several decades. Their medicinal importance as anticancer, antioxidant, antimicrobial, and antidiabetic has been explored. Continual efforts have been made toward activity enhancement that can be achieved by making suitable structural alterations or by ...
Ekhlakh Veg   +5 more
wiley   +1 more source

Paradoxical Deterioration During Anti-Tuberculous Therapy in Non-HIV-Infected Patients with Pleural Tuberculosis: A Pragmatic Approach

open access: yesEuropean Journal of Case Reports in Internal Medicine, 2016
We report a case of paradoxical deterioration. A male patient diagnosed with pleural tuberculosis, but who was not infected with human immunodeficiency virus (HIV), experienced clinical deterioration 3 weeks after the initiation of anti-tuberculous ...
Luis Corral-Gudino   +3 more
doaj   +1 more source

Cooperative Heterogeneous Deep Reinforcement Learning [PDF]

open access: yesarXiv, 2020
Numerous deep reinforcement learning agents have been proposed, and each of them has its strengths and flaws. In this work, we present a Cooperative Heterogeneous Deep Reinforcement Learning (CHDRL) framework that can learn a policy by integrating the advantages of heterogeneous agents.
arxiv  

A Systematic Review of Synthetic and Anticancer and Antimicrobial Activity of Quinazoline/Quinazolin‐4‐one Analogues

open access: yesChemistryOpen, EarlyView.
Quinazoline represents an important class of heterocycles with diverse medicinal and pharmacological significance. This review systematically examines scholarly efforts toward understanding different synthetic pathways emphasizing the role of metal and non‐metal catalysts including some miscellaneous reagents employed in the synthesis of quinazoline ...
Neha Manhas   +4 more
wiley   +1 more source

Synthesis and Biological Evaluation of 2-(3-Fluoro-4-nitro phenoxy)-N-phenylacetamide Derivatives as Novel Potential Affordable Antitubercular Agents

open access: yesMolecules, 2012
A novel series of 2-(3-fluoro-4-nitrophenoxy)-N-phenylacetamide compounds were designed, synthesized and in vitro assessed for their antitubercular activities by a microdilution method.
Yu-Quan Wei   +8 more
doaj   +1 more source

PYRAZOLINES AS POTENT ANTITUBERCULAR AND CYTOTOXIC AGENTS [PDF]

open access: yes, 2017
Objective: Pyrazolines are known to exhibit different biological and pharmacological properties such as anticancer, antibacterial, antifungal and antitubercular activities.
K, Ishwar Bhat, Kumar, Abhishek
core   +1 more source

The Halo Vest Immobilization for Craniocervical Junction Tuberculosis: A Comparison of Treatment Options

open access: yesOrthopaedic Surgery, EarlyView.
This study aimed to evaluate the clinical outcomes and safety of Halo vest (HV) immobilization in treating craniovertebral junction tuberculosis, compared with occipitocervical fusion. The results showed that patients receiving HV treatment had greater improvement in neck function compared with those undergoing occipitocervical fusion.
Yunfeng Wu   +5 more
wiley   +1 more source

Non linear Prediction of Antitubercular Activity Of Oxazolines and Oxazoles derivatives Making Use of Compact TS-Fuzzy models Through Clustering with orthogonal least sqaure technique and Fuzzy identification system [PDF]

open access: yesarXiv, 2014
The prediction of uncertain and predictive nonlinear systems is an important and challenging problem. Fuzzy logic models are often a good choice to describe such systems however in many cases these become complex soon. commonlly, too less effort is put into descriptor selection and in the creation of suitable local rules.
arxiv  

Computational Design, Synthesis, and Biological Assessment of Some Pyrrolo[3,4‐c]Pyrroles Targeting Mycobacterium Tuberculosis

open access: yesChemistrySelect, Volume 10, Issue 17, May 5, 2025.
A new set of spirooxindole‐ and spiroindenoquinoxaline‐derived pyrrolo[3,4‐c] pyrroles has been synthesized through atom‐economic one‐pot multicomponent reactions. Based on the results, compounds 4b and 5a demonstrated promising Glide scores and exhibited strong binding affinity with decaprenylphosphoryl‐β‐D‐ribofuranose oxidoreductase.
Mathiyazhagan Lavanya   +8 more
wiley   +1 more source

Quinoxaline 1,4-di-N-oxide and the Potential for Treating Tuberculosis [PDF]

open access: yes, 2011
New drugs active against drug-resistant tuberculosis are urgently needed to extend the range of TB treatment options to cover drug resistant infections.
Aldana, I. (Ignacio)   +11 more
core  

Home - About - Disclaimer - Privacy