Results 81 to 90 of about 3,184,601 (122)

Environmental fungi target thiol homeostasis to compete with Mycobacterium tuberculosis.

PLoS Biology
Mycobacterial species in nature are found in abundance in sphagnum peat bogs where they compete for nutrients with a variety of microorganisms including fungi. We screened a collection of fungi isolated from sphagnum bogs by co-culture with Mycobacterium
Neha Malhotra, Sangmi Oh, Peter Finin, Jessica Medrano, Jenna Andrews, Michael Goodwin, Tovah E Markowitz, Justin Lack, Helena I M Boshoff, Clifton Earl Barry   +9 more
doaj   +1 more source

Reciprocal Collision Avoidance for General Nonlinear Agents using Reinforcement Learning [PDF]

arXiv, 2019
Finding feasible and collision-free paths for multiple nonlinear agents is challenging in the decentralized scenarios due to limited available information of other agents and complex dynamics constraints. In this paper, we propose a fast multi-agent collision avoidance algorithm for general nonlinear agents with continuous action space, where each ...
arxiv  

Phytogenic silver, gold, and bimetallic nanoparticles as novel antitubercular agents

International Journal of Nanomedicine, 2016
Richa Singh,1 Laxman Nawale,2 Manisha Arkile,2 Sweety Wadhwani,1 Utkarsha Shedbalkar,1 Snehal Chopade,1 Dhiman Sarkar,2 Balu Ananda Chopade1,3 1Department of Microbiology, Savitribai Phule Pune University, 2Combichem-Bioresource Center, Organic ...
Singh R, Nawale L, Arkile M, Wadhwani S, Shedbalkar U, Chopade S, Sarkar D, Chopade BA   +7 more
doaj  

4-[10-(Methoxy-benzyl)-anthracen-9-yl]-phenol derivatives as new antitubercular agents

ARKIVOC, 2005
Gautam Panda, Jitendra Kumar Mishra, Sudhir Sinha, Anil K. Gaikwad, Anil K. Srivastava, Ranjana Srivastava, Brahm S. Srivastava   +6 more
doaj   +1 more source

Responsible AI Agents [PDF]

arXiv
Thanks to advances in large language models, a new type of software agent, the artificial intelligence (AI) agent, has entered the marketplace. Companies such as OpenAI, Google, Microsoft, and Salesforce promise their AI Agents will go from generating passive text to executing tasks.
arxiv  

SAGA: A Security Architecture for Governing AI Agentic Systems [PDF]

arXiv
Large Language Model (LLM)-based agents increasingly interact, collaborate, and delegate tasks to one another autonomously with minimal human interaction. Industry guidelines for agentic system governance emphasize the need for users to maintain comprehensive control over their agents, mitigating potential damage from malicious agents. Several proposed
arxiv  

Real World Experience of Bedaquiline-Based Anti-Tubercular Regime in Multi-Drug Resistant Tuberculosis.

International Journal of Medical Students
BACKGROUND: Tuberculosis is an important public healthcare problem in our country. Drug-resistant Tuberculosis is like a smoldering fire that if not controlled will flare up to an uncontrolled inferno. The conventional therapy for multidrug-resistant TB
Vikas Marwah , Robin Choudhary , I M Pandey, Sandeep Rana, Anmol Sharma, Srishti Tripathy, Virender Malik, Shrinath V, Jyothis MC, Tentu Ajay   +9 more
doaj  

Directly observed treatment, short-course strategy and multidrug-resistant tuberculosis: are any modifications required?

Bulletin of the World Health Organization
Multidrug-resistant tuberculosis (MDRTB) should be defined as tuberculosis with resistance to at least isoniazid and rifampicin because these drugs are the cornerstone of short-course chemotherapy, and combined isoniazid and rifampicin resistance ...
I. Bastian, L. Rigouts, A. Van Deun, F. Portaels   +3 more
doaj   +1 more source

Exploring the structural aspects of alanine racemase enzyme for antitubercular drug discovery – a computational approach

Journal of Applied Pharmaceutical Research
Background: Tuberculosis (TB) is a communicable disease that is a significant cause of ill health and one of the leading causes of death worldwide. The current antibiotics have been pivotal in managing TB to a greater extent.
Unni Jayaram, Parthan Anilkumar, Fathima Rifana Yousuf, Graceson Jose   +3 more
doaj   +1 more source

Pharmacophore modelling, QSAR study, molecular docking and insilico ADME prediction of 1,2,3-triazole and pyrazolopyridones as DprE1 inhibitor antitubercular agents

SN Applied Sciences, 2020
D. Panigrahi, Amiyakanta Mishra, S. Sahu
semanticscholar   +1 more source