Results 101 to 110 of about 3,707,085 (259)

Improvement in Outcomes with a New Bedaquiline-based Regimen in Postoperative Cases of Drug-resistant Tuberculosis of the Spine: A Case Series [PDF]

Journal of Clinical and Diagnostic Research
The incidence of drug-resistant strains of Tuberculosis (TB) is rising at an alarming rate. With the emergence of newer drug-resistant strains, managing the disease with existing antitubercular agents is becoming increasingly difficult. Few studies exist
Soutrik Kundu, Sarvan Singh
doaj   +1 more source

Synthesis of Some 4-Thiazolidinone Derivatives as Antitubercular Agents [PDF]

Journal of Sciences, Islamic Republic of Iran, 2004
Substituted Schiff's bases 2a-o prepared by the treatment of 2-amino-4-(?-methoxyiminocarbomethoxymethyl)-thiazole 1 with different aromatic aldehydes, on cyclocondensation with mercaptoaceticacid and mercaptopropionicacid in dry benzene furnished ...
doaj  

A facile synthesis of novel indole derivatives as potential antitubercular agents

Journal of Taibah University for Science, 2017
A novel series of 5,5-dimethyl-11-phenyl-4b,5,5a,10,10a,11,11a,12-octahydro-10,11,12-triaza-indeno[2,1-b]fluorenes 3a–3l were prepared by reacting oxindole, aryl amines and acetone using dibutylamine as an organocatalyst via simultaneous Knoevenagel ...
Gulzar A. Khan, Javeed A. War, Arun Kumar, Imtiyaz A. Sheikh, Aarti Saxena, Ratnesh Das   +5 more
doaj   +1 more source

Second-line antitubercular agents and their adverse effects [PDF]

Vojnosanitetski Pregled, 2006
Nagorni-Obradović Ljudmila, Škodrić-Trifunović Vesna   +1 more
doaj   +1 more source

Identification of Axinellamines A and B as Anti-Tubercular Agents

Marine Drugs
Tuberculosis remains a significant global health pandemic. There is an urgent need for new anti-tubercular agents to combat the rising incidence of drug resistance and to offer effective and additive therapeutic options.
Emily J. Strong, Lendl Tan, Sasha Hayes, Hayden Whyte, Rohan A. Davis, Nicholas P. West   +5 more
doaj   +1 more source

Discovery of meta-Amido Bromophenols as New Antitubercular Agents.

Chemical and pharmaceutical bulletin, 2019
A series of meta-amido bromophenol derivatives were designed and synthesized. The compounds were found to potently inhibit the growth of Mycobacterium tuberculosis H37Ra. They also exhibited moderate inhibitory activity against Mycobacterium tuberculosis
Jie-ping Liang, Yunxiang Tang, Xiang-zheng Tang, Hua-ju Liang, Yamin Gao, Cuiting Fang, Tianyu Zhang, M. Yan   +7 more
semanticscholar   +1 more source

_M. tuberculosis_ interactome analysis unravels potential pathways to drug resistance [PDF]

, 2008
Drug resistance is a major problem for combating tuberculosis. Lack of understanding of how resistance emerges in bacteria upon drug treatment limits our ability to counter resistance.
Karthik Raman, Nagasuma Chandra
core   +1 more source

Synthesis and Structure-Activity Relationships of a New Class of Oxadiazoles Targeting DprE1 as Antitubercular Agents. [PDF]

ACS Med Chem Lett, 2023
Yadav VD, Boshoff HI, Trifonov L, Roma JSO, Ioerger TR, Barry CE, Oh S.   +6 more
europepmc   +1 more source

Structure-directed identification of pyridine-2-methylamine derivatives as MmpL3 inhibitors for use as antitubercular agents. [PDF]

Eur J Med Chem, 2023
Wen Y, Lun S, Jiao Y, Zhang W, Liu T, Yang F, Tang J, Bishai WR, Yu LF.   +8 more
europepmc   +1 more source

4-[10-(Methoxy-benzyl)-anthracen-9-yl]-phenol derivatives as new antitubercular agents

ARKIVOC, 2005
Gautam Panda, Jitendra Kumar Mishra, Sudhir Sinha, Anil K. Gaikwad, Anil K. Srivastava, Ranjana Srivastava, Brahm S. Srivastava   +6 more
doaj   +1 more source