Results 101 to 110 of about 1,577,899 (206)

The recent advances in benzimidazole-based antimicrobials and antitubercular agents

Future Journal of Pharmaceutical Sciences
Background Benzimidazole, a fused heterocyclic compound, has emerged as a privileged structure in medicinal chemistry due to its broad spectrum of biological activities, particularly in antimicrobial and antitubercular (anti-TB) applications.
Abdalrahman Tarek, Maiy Y. Jaballah, Eman Z. Elrazaz, Nermin Samir   +3 more
doaj   +1 more source

Evaluation of antitubercular drug insertion into preformed dipalmitoylphosphatidylcholine monolayers

, 2008
Insertion profiles of antitubercular drugs isoniazid (INH), rifampicin (RFM) and ethambutol (ETH) into dipalmitoylphosphatidylcholine (DPPC) membrane models were evaluated by Langmuir monolayer technique.
CHIMOTE, G, BANERJEE, R
core   +1 more source

Design, Synthesis, and Biological Evaluation of Pyrazolo[1,5‑a]pyridine-3-carboxamides as Novel Antitubercular Agents

, 2015
A series of pyrazolo­[1,5-a]­pyridine-3-carboxamide derivatives were designed and synthesized as new anti-Mycobacterium tuberculosis (Mtb) agents. The compounds exhibit promising in vitro potency with nanomolar MIC values against the drug susceptive ...
Zhengchao Tu (542105), Bangxing Wang (701068), Moses Njire (1571023), Baojie Wan (410986), Ke Ding (309244), Tian Wu (644347), Scott G. Franzblauc (1571026), Junting Wan (701071), Jian Tang (109884), Tianyu Zhang (188439), Xiaoyun Lu (1390002)   +10 more
core   +1 more source

Isoxazole carboxylic acid methyl ester-based urea and thiourea derivatives as promising antitubercular agents. [PDF]

Mol Divers, 2023
Sahoo SK, Ommi O, Maddipatla S, Singh P, Ahmad MN, Kaul G, Nanduri S, Dasgupta A, Chopra S, Yaddanapudi VM.   +9 more
europepmc   +1 more source

Review of Evidence for Measuring Drug Concentrations of First-Line Antitubercular Agents in Adults

, 2014
Measurement of drug concentrations and performing therapeutic drug monitoring (TDM) are widely used to optimize efficacy and safety of many commonly used drugs today.
Ensom, Mary H.H., Wilby, Kyle John, Marra, Fawziah   +2 more
core   +1 more source

Synthesis, Biological Evaluation and Computational Studies of New Hydrazide Derivatives Containing 1,3,4-Oxadiazole as Antitubercular Agents. [PDF]

Int J Mol Sci, 2022
Zampieri D, Fortuna S, Romano M, De Logu A, Cabiddu G, Sanna A, Mamolo MG.   +6 more
europepmc   +1 more source

Real World Experience of Bedaquiline-Based Anti-Tubercular Regime in Multi-Drug Resistant Tuberculosis.

International Journal of Medical Students
BACKGROUND: Tuberculosis is an important public healthcare problem in our country. Drug-resistant Tuberculosis is like a smoldering fire that if not controlled will flare up to an uncontrolled inferno. The conventional therapy for multidrug-resistant TB
Vikas Marwah , Robin Choudhary , I M Pandey, Sandeep Rana, Anmol Sharma, Srishti Tripathy, Virender Malik, Shrinath V, Jyothis MC, Tentu Ajay   +9 more
doaj  

N'-Substituted 4-Phenylpicolinohydrazonamides with Thiosemicarbazone Moiety as New Potential Antitubercular Agents: Synthesis, Structure and Evaluation of Antimicrobial Activity. [PDF]

Materials (Basel), 2022
Gobis K, Szczesio M, Olczak A, Mazerant-Politowicz I, Ziembicka D, Pacholczyk-Sienicka B, Augustynowicz-Kopeć E, Głogowska A, Korona-Głowniak I, Fruziński A.   +9 more
europepmc   +1 more source

Comparison of the Efficacy of Two Novel Antitubercular Agents in Free and Liposome-Encapsulated Formulations. [PDF]

Int J Mol Sci, 2021
Kósa N, Zolcsák Á, Voszka I, Csík G, Horváti K, Horváth L, Bősze S, Herenyi L.   +7 more
europepmc   +1 more source

New Quinoline-Urea-Benzothiazole Hybrids as Promising Antitubercular Agents: Synthesis, In Vitro Antitubercular Activity, Cytotoxicity Studies, and In Silico ADME Profiling. [PDF]

Pharmaceuticals (Basel), 2022
Moodley R, Mashaba C, Rakodi GH, Ncube NB, Maphoru MV, Balogun MO, Jordan A, Warner DF, Khan R, Tukulula M.   +9 more
europepmc   +1 more source