Results 111 to 120 of about 3,707,085 (259)

Molecular docking and pharmacokinetics of benzimidazole-based FtsZ inhibitors for tuberculosis

Scientific Reports
Benzimidazole derivatives are privileged heterocyclic scaffolds with broad-spectrum pharmacological activities, notably antitubercular and antibacterial.
Pratiksha N. Sonwane, Manoj R. Kumbhare
doaj   +1 more source

Complications leading to hospitalization due to consumption of anti-TB drugs in patients with tuberculosis in Gorgan, Iran (2007-12) [PDF]

, 2015
Background and Objective: Anti tuberculosis drugs therapy is the most effective method for controling the tuberculosis (TB). Early detection and appropriate treatment can prevent the TB-drug resistance.
Abbasi, A., Ghasemi Kebria, F., Hashemi Fard, A., Khodabakhshi, B., Khosravian, M.   +4 more
core  

Investigating the Roles of Active Site Residues in Mycobacterium tuberculosis Indole-3-glycerol Phosphate Synthase, a Potential Target for Antitubercular Agents. [PDF]

ACS Bio Med Chem Au, 2023
Konas DW, Cho S, Thomas OD, Bhatti MM, Leon Hernandez K, Moran C, Booter H, Candela T, Lacap J, McFadden P, van den Berg S, Welter AM, Peralta A, Janson CA, Catalano J, Goodey NM.   +15 more
europepmc   +1 more source

Environmental fungi target thiol homeostasis to compete with Mycobacterium tuberculosis.

PLoS Biology
Mycobacterial species in nature are found in abundance in sphagnum peat bogs where they compete for nutrients with a variety of microorganisms including fungi. We screened a collection of fungi isolated from sphagnum bogs by co-culture with Mycobacterium
Neha Malhotra, Sangmi Oh, Peter Finin, Jessica Medrano, Jenna Andrews, Michael Goodwin, Tovah E Markowitz, Justin Lack, Helena I M Boshoff, Clifton Earl Barry   +9 more
doaj   +1 more source

Drug Reaction with Eosinophilia and Systemic Symptoms Syndrome in Pulmonary Tuberculosis Patient with Type 2 Respiratory Failure and Sepsis

International Journal of Mycobacteriology
While anti-tuberculosis drugs (ATDs) are essential for tuberculosis (TB) treatment, they can induce severe hypersensitivity reactions, including drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome.
Brigita Sanina Manullang, Isnin Anang Marhana   +1 more
doaj   +1 more source

Molecular insights into Mmpl3 leads to the development of novel indole-2-carboxamides as antitubercular agents. [PDF]

Mol Syst Des Eng, 2022
Ray R, Birangal SR, Fathima F, Boshoff HI, Forbes HE, Chandrashekhar RH, Shenoy GG.   +6 more
europepmc   +1 more source

Isoxazole carboxylic acid methyl ester-based urea and thiourea derivatives as promising antitubercular agents. [PDF]

Mol Divers, 2023
Sahoo SK, Ommi O, Maddipatla S, Singh P, Ahmad MN, Kaul G, Nanduri S, Dasgupta A, Chopra S, Yaddanapudi VM.   +9 more
europepmc   +1 more source

6-Amidinopurines as convenient precursors to pyrimido[5,4-d]pyrimidines for sar studies on Mycobacterium tuberculosis [PDF]

, 2012
Thanks are due to University of Minho and Fundação para a Ciência e Tecnologia for financial support (project nºF-COMP-01-0124-FEDER-022716 (ref. FCT PEst-/QUI/UI0686/2011) FEDER-COMPETE, FCT-Portugal and PhD grant awarded to Ana Bacelar SRFH/BD/24959 ...
Bacelar, Ana Helena Dias, Brito, A., Carvalho, M. Alice, Proença, M. Fernanda R. P., Rocha, Ashly   +4 more
core  

Multidrug-resistant tuberculosis

Revista Ciencias Biomédicas, 2013
Introduction: tuberculosis is an increasing problem of global health and the microbialdrug resistance a generating element of worry.Clinical case: 19 year-old patient, who admitted to the emergency room for presentinghemoptysis and who had history of ...
Álvarez-Gaviria Manuel, De-la-Vega Fernando, Bello-Espinosa Ariel, Lora-Hurtado Merle, Navas-Torrejano Diana, Herazo-Bustos Cherina   +5 more
doaj  

Synthesis, Biological Evaluation and Computational Studies of New Hydrazide Derivatives Containing 1,3,4-Oxadiazole as Antitubercular Agents. [PDF]

Int J Mol Sci, 2022
Zampieri D, Fortuna S, Romano M, De Logu A, Cabiddu G, Sanna A, Mamolo MG.   +6 more
europepmc   +1 more source