Results 71 to 80 of about 16,260 (178)

Investigating the Roles of Active Site Residues in Mycobacterium tuberculosis Indole-3-glycerol Phosphate Synthase, a Potential Target for Antitubercular Agents. [PDF]

ACS Bio Med Chem Au, 2023
Konas DW, Cho S, Thomas OD, Bhatti MM, Leon Hernandez K, Moran C, Booter H, Candela T, Lacap J, McFadden P, van den Berg S, Welter AM, Peralta A, Janson CA, Catalano J, Goodey NM.   +15 more
europepmc   +1 more source

Multidrug-resistant tuberculosis

Revista Ciencias Biomédicas, 2013
Introduction: tuberculosis is an increasing problem of global health and the microbialdrug resistance a generating element of worry.Clinical case: 19 year-old patient, who admitted to the emergency room for presentinghemoptysis and who had history of ...
Álvarez-Gaviria Manuel, De-la-Vega Fernando, Bello-Espinosa Ariel, Lora-Hurtado Merle, Navas-Torrejano Diana, Herazo-Bustos Cherina   +5 more
doaj  

Pyrazinamide-derived hydrazone outperforms pyrazinamide activity in Mycobacterium tuberculosis DM97: an in vitro and in silico study

Eclética Química
Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis (MTB). Pyrazinamide (PZA) is a prodrug used in first-lines treatment. New drugs proposals are urgent, given the increased resistance to antimicrobials such as PZA.
Christian Aliaga Paucar, Jesús Antonio Alvarado-Huayhuaz, Henrry Rene Gutierrez Vega, Ramirez Panti Rocio, Mirko Zimic Peralta, Patricia Sheen Cortavarria, Ana Valderrama Negrón   +6 more
doaj   +1 more source

Molecular insights into Mmpl3 leads to the development of novel indole-2-carboxamides as antitubercular agents. [PDF]

Mol Syst Des Eng, 2022
Ray R, Birangal SR, Fathima F, Boshoff HI, Forbes HE, Chandrashekhar RH, Shenoy GG.   +6 more
europepmc   +1 more source

Drug Reaction with Eosinophilia and Systemic Symptoms Syndrome in Pulmonary Tuberculosis Patient with Type 2 Respiratory Failure and Sepsis

International Journal of Mycobacteriology
While anti-tuberculosis drugs (ATDs) are essential for tuberculosis (TB) treatment, they can induce severe hypersensitivity reactions, including drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome.
Brigita Sanina Manullang, Isnin Anang Marhana   +1 more
doaj   +1 more source

Isoxazole carboxylic acid methyl ester-based urea and thiourea derivatives as promising antitubercular agents. [PDF]

Mol Divers, 2023
Sahoo SK, Ommi O, Maddipatla S, Singh P, Ahmad MN, Kaul G, Nanduri S, Dasgupta A, Chopra S, Yaddanapudi VM.   +9 more
europepmc   +1 more source

Synthesis, Biological Evaluation and Computational Studies of New Hydrazide Derivatives Containing 1,3,4-Oxadiazole as Antitubercular Agents. [PDF]

Int J Mol Sci, 2022
Zampieri D, Fortuna S, Romano M, De Logu A, Cabiddu G, Sanna A, Mamolo MG.   +6 more
europepmc   +1 more source

Antitubercular Agent [PDF]

, 2020
openaire   +1 more source

Intensive Management of a Patient with HIV, Active Tuberculosis, and COVID-19: A Multidisciplinary Approach in the Intensive Care Unit

Life
Coinfection with HIV, active tuberculosis, and COVID-19 is rare but markedly increases mortality risk and complicates treatment due to the interactions between these infections.
Brayan Ricardo Mosquera-Arias, Valeria Sanclemente-Cardoza, Jose Luis Estela-Zape   +2 more
doaj   +1 more source

N'-Substituted 4-Phenylpicolinohydrazonamides with Thiosemicarbazone Moiety as New Potential Antitubercular Agents: Synthesis, Structure and Evaluation of Antimicrobial Activity. [PDF]

Materials (Basel), 2022
Gobis K, Szczesio M, Olczak A, Mazerant-Politowicz I, Ziembicka D, Pacholczyk-Sienicka B, Augustynowicz-Kopeć E, Głogowska A, Korona-Głowniak I, Fruziński A.   +9 more
europepmc   +1 more source