Results 71 to 80 of about 17,370 (212)

Tetrahydroisoquinolines affect the whole-cell phenotype of Mycobacterium tuberculosis by inhibiting the ATP-dependent MurE ligase. [PDF]

, 2015
(S)-Leucoxine, isolated from the Colombian Lauraceae tree Rhodostemonodaphne crenaticupula Madriñan, was found to inhibit the growth of Mycobacterium tuberculosis H37Rv.
Mortazavi, Parisa Nakhostin, Munshi, T, Bhakta, S, Maitra, A, Cuca, L.E., Pesnot, T, Pesnot, T., Hailes, HC, Angell, R, Barrera, DA, Needham, D, Hailes, H.C., Bhakta, Sanjib, Davies, H.M., Gershater, MC, Davies, HM, Barrera, D.A., Evangelopoulos, Dimitrios, Cuca, LE, McMahon, E, Maitra, Arundhati, Redmond, J.M., Ward, J.M., Evangelopoulos, D, Mortazavi, PN, Munshi, Tulika, Gershater, M.C., Ward, JM, Lamming, E.D., Redmond, JM, McMahon, E., Angell, R., Guzman, JD, Guzman, Juan D., Needham, D., Lamming, ED   +35 more
core   +1 more source

Synthesis and Antitubercular Activity of Some Novel Thiazolidinone Derivatives

, 2012
Purpose: To synthesize and characterize novel thiazolidinone derivatives and screen them for antitubercular activity. Methods: A series of twelve novel thiazolidinones 4a-l have been synthesized by cyclocondensation of various Schiff bases of amino ...
Sikarwar, Mukesh S, Malipeddi, H, Karigar, AA, Malipeddi, VR, Malipeddi, Himaja, Karigar, Asif A, Malipeddi, Venkata Ramana, Sikarwar, MS   +7 more
core   +3 more sources

A facile synthesis of novel indole derivatives as potential antitubercular agents

Journal of Taibah University for Science, 2017
A novel series of 5,5-dimethyl-11-phenyl-4b,5,5a,10,10a,11,11a,12-octahydro-10,11,12-triaza-indeno[2,1-b]fluorenes 3a–3l were prepared by reacting oxindole, aryl amines and acetone using dibutylamine as an organocatalyst via simultaneous Knoevenagel ...
Gulzar A. Khan, Javeed A. War, Arun Kumar, Imtiyaz A. Sheikh, Aarti Saxena, Ratnesh Das   +5 more
doaj   +1 more source

Novel 1,4-substituted-1,2,3-triazoles as antitubercular agents.

, 2015
Tuberculosis (TB) remains a pressing unmet medical need, particularly with the emergence of multidrug-resistant and extensively drug-resistant tuberculosis.
Luke Henderson (13082367), JM Altimari (14466177), A Sajid (13410789), SC Hockey (14527817), HI Boshoff (18718477)   +4 more
core  

The Synthesis and Evaluation of N-Heterocycles as Antitubercular Agents

, 2021
Tuberculosis, the disease caused by the microbial pathogen Mycobacterium tuberculosis, is one of the world’s leading infectious causes of death. In 2019, the World Health Organisation estimated that 10 million new cases of tuberculosis were contracted ...
Martin, Liam Thomas
core  

Estudo farmacocinético de um análogo lipofílico da isoniazida, denominado JVA, administrado em camundongos [PDF]

, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-Graduação em FarmacologiaA tuberculose (TB) é uma infecção das vias aéreas causada pela inalação de gotículas em suspensão do Mycobacterium ...
Roman, Mariane
core  

Synthesis of Some 4-Thiazolidinone Derivatives as Antitubercular Agents [PDF]

Journal of Sciences, Islamic Republic of Iran, 2004
Substituted Schiff's bases 2a-o prepared by the treatment of 2-amino-4-(?-methoxyiminocarbomethoxymethyl)-thiazole 1 with different aromatic aldehydes, on cyclocondensation with mercaptoaceticacid and mercaptopropionicacid in dry benzene furnished ...
doaj  

Inside Cover: Novel 1,4-Substituted-1,2,3-Triazoles as Antitubercular Agents (ChemMedChem 5/2015)

, 2015
Inside Cover: Novel 1,4-Substituted-1,2,3-Triazoles as Antitubercular Agents (ChemMedChem 5 ...
Luke Henderson (13082367), Helena I Boshoff (12018203), Jarrad M Altimari (17990131), Andaleeb Sajid (228010), Samantha C Hockey (17990134)   +4 more
core  

Supramolecular modification of selected antitubercular drugs

, 2010
Includes abstract.Includes bibliographical references.The author's objective was to prepare new solid phases of the antitubercular drug isoxyl [specifically polymorphs, solvates, cyclodextrin (CD) inclusion complexes and cocrystals] and to isolate and ...
Li, Jinjing
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Construction and functionalization of fused pyridine ring leading to novel compounds as potential antitubercular agents

, 2012
A series of fused and functionalized pyridine derivatives were designed, synthesized and tested for their potential antitubercular properties. All these novel compounds were prepared by using multistep methods involving the construction of pyridine ring ...
Kapavarapu, Ravikumar, Reiser, Oliver, Wan, Baojie, Iqbal, Javed, Pal, Manojit, Dulla, Balakrishna, Franzblau, Scott G.   +6 more
core   +1 more source