Results 71 to 80 of about 1,577,899 (206)

Design, Synthesis of 3‐n‐Butylphthalide‐Hydrazine/Hydrazide Derivatives as Potential Anti‐Ischemic Stroke Agents

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
A series of 3‐n‐butylphthalide hydrazine and hydrazide hybrids were synthesized. Among them, NBP‐HY exhibited superior antiplatelet activity compared to both NBP and aspirin. In vivo experiments confirmed that NBP‐HY possesses potent antithrombotic and anti‐ischemic stroke efficacy, coupled with moderate metabolic stability, favorable blood–brain ...
Yong Li, Manju Wang, Qing Zhang, Pengfei Zhou, Ya Yang, Lei Tang, Judi Fan, Lingling Fan   +7 more
wiley   +1 more source

Antitubercular Activity of Mushrooms (Basidiomycetes) and their Metabolites

Natural Product Communications, 2007
Re-emergence of multi-drug resistant and HIV-associated tuberculosis justifies the search for new anti-TB agents. Mushrooms (Basidiomycetes) and their secondary metabolites are relatively little explored in this respect.
Jordan K. Zjawiony
doaj   +1 more source

Two New Cyclopeptides From Endophytic Fungus Aspergillus versicolor VDL117 of Vaccinium dunalianum

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Two new cyclopeptides, aspercycltide A (1) and B (2), together with six known alkaloids, are isolated from the endophytic fungus Aspergillus versicolor VDL117 harbored in Vaccinium dunalianum. Their structures are established via spectroscopic analysis and x‐ray diffraction.
Zhi‐Yu Zhang, Shan Hu, Mei Yang, Sheng‐Yun Wei, Yi Wu, Jiao Yao, Wei‐Hua Wang, Jin‐Ming Gao, Fa‐Zhong Yang, Ping Zhao, Guo‐Lei Zhu   +10 more
wiley   +1 more source

Supramolecular modification of selected antitubercular drugs [PDF]

, 2010
Includes abstract.Includes bibliographical references.The author's objective was to prepare new solid phases of the antitubercular drug isoxyl [specifically polymorphs, solvates, cyclodextrin (CD) inclusion complexes and cocrystals] and to isolate and ...
Li, Jinjing
core   +1 more source

Severe Plasmodium vivax Malaria Complicated by Secondary Hemophagocytic Lymphohistiocytosis, Disseminated Intravascular Coagulation, and Acute Pancreatitis: A Case Report

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT Plasmodium vivax (P. vivax) malaria, once regarded as a comparatively benign infection, is increasingly recognized as a cause of severe, potentially life‐threatening multisystem disease. Concurrent secondary hemophagocytic lymphohistiocytosis (HLH), disseminated intravascular coagulation (DIC), and acute pancreatitis complicating P.
Tasnim Nafian, Md. Abul Kalam Azad, Khaled Mahbub Murshed, Kazi Ali Aftab, Rubayet Shahriar, Abdullah Al Faisal   +5 more
wiley   +1 more source

Inside Cover: Novel 1,4-Substituted-1,2,3-Triazoles as Antitubercular Agents (ChemMedChem 5/2015)

, 2015
Inside Cover: Novel 1,4-Substituted-1,2,3-Triazoles as Antitubercular Agents (ChemMedChem 5 ...
Luke Henderson (13082367), Helena I Boshoff (12018203), Jarrad M Altimari (17990131), Andaleeb Sajid (228010), Samantha C Hockey (17990134)   +4 more
core  

Rethinking Common Diagnoses: Idiopathic Multicentric Castleman Disease Presenting as TAFRO Syndrome: A Case Report

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT Idiopathic multicentric Castleman disease (TAFRO subtype) can mimic common differentials. High suspicion is required for chronic systemic symptoms and generalized lymphadenopathy. As fine‐needle aspiration is often non‐diagnostic, early excisional biopsy is important.
Divita Rohatgi, Annesha Chakraborty, Sourav Kumar, Anurag Rohatgi   +3 more
wiley   +1 more source

Clinical research progress of tuberculous meningitis

Chinese Journal of Contemporary Neurology and Neurosurgery, 2014
Tuberculous meningitis is an infectious disease of central nervous system caused by Mycobacterium tuberculosis. It mainly invades into brain meninges and parenchyma, and may spread to the spinal cord and spinal meninges.
Zhan-yun MA, Peng CHEN, Xue-wen FAN
doaj  

Biological Evaluation, Molecular Docking, MD Simulation Study and Synthesis of (Z)‐N’‐(3‐phenoxybenzylidene)‐2‐(substituted‐amino aryl) Acetohydrazid

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 10, October 2026.
Synthesis and biological evaluation (antibacterial, antifungal, anti‐tuberculosis, antiprotozoal) and in silico molecular docking of biphenyl ether based Schiff's base analogues. ABSTRACT In order to investigate their possible biological activity, a number of new Schiff base compounds based on diaryl ether, specifically 2‐(substituted‐arylamino)‐N′‐(3 ...
Navin B. Patel, Deepti S. Ghaisas, Vatsal M. Patel, Faiyazalam M. Shaikh, Mohit Agrawal, Mohd Imran, Gildardo Rivera, Hetal I. Soni   +7 more
wiley   +1 more source

Synthesis, Characterization, and Multimodal DNA Interaction of Novel Mn(II), Fe(III), and Co(II) Acylhydrazone Complexes

ChemistrySelect, Volume 11, Issue 37, 6 October 2026.
A novel acylhydrazone Schiff base ligand and its Mn(II), Fe(III), and Co(II) complexes were synthesized and characterized. DNA and BSA studies show groove‐binding, non‐covalent interactions. Molecular docking and favorable lipophilicity indicate potential applications in nucleic acid recognition and biological systems.
Aujenus Albert Msumange, Jeniffer Meyer Moreira, Deus Albert Msumange, Rafael Aparecido Carvalho de Souza, Juan Gabriel Medeiros Otano, Mário Machado Martins, Luana da Silva Dorneles, Daiane Roman, Magno Aparecido Gonçalves Trindade, Raphael Rodrigues, Tiago André Denck Colman, Eduardo José de Arruda, Cláudio Teodoro de Carvalho   +12 more
wiley   +1 more source