Results 111 to 120 of about 840,802 (388)
Research Progress on the Role of GSDME-mediated Pyroptosis in the Treatment of Lung Cancer
Chinese Journal of Lung CancerLung cancer causes a significant threat to human health. Despite considerable advancements in the treatment technologies in recent years, the five-year survival rate for lung cancer patients remains low.
Huan LI, Xudong TANG
doaj +1 more source
Extraction, Chemical Composition, and Anticancer Potential of Origanum onites L. Essential Oil
Molecules, 2019 Origanum species are plants rich in volatile oils that are mainly used for culinary purposes. In recent years, there has been a growing interest in the biological activities of their essential oils. Origanum onites L.
Katerina Spyridopoulou +8 more
doaj +1 more source
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Synthesis and Antiangiogenic Activity of Novel Gambogic Acid Derivatives
Molecules, 2012 Gambogic acid (GA) is in a phase II clinical trial as an antitumor and antiangiogenesis agent. In this study, 36 GA derivatives were synthesized and screened in a zebrafish model to evaluate their antiangiogenic activity and toxicity.
Li-Juan Chen +11 more
doaj +1 more source
Bacterial outer membrane vesicles suppress tumor by interferon-γ-mediated antitumor response
Nature Communications, 2017 Gram-negative bacteria actively secrete outer membrane vesicles, spherical nano-meter-sized proteolipids enriched with outer membrane proteins, to the surroundings.
O. Y. Kim +7 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
Celecoxib in breast cancer prevention and therapy. [PDF]
, 2018 Breast cancer has a high incidence worldwide. The results of substantial studis reveal that inflammation plays an important role in the initiation, development, and aggressiveness of many malignancies. The use of celecoxib, a novel NSAID, is repetitively
Cao, Wei +4 more
core
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
Comparative Effect of Maitake Pro4x with Chemotherapy Breast Cancer Treatment [PDF]
, 2017 Conventional treatments for breast cancer involve surgery followed by radiation and hormonal therapy and/or chemotherapy. Some of these treatments have toxic side effects.
Aguilera Braico, Diego Máximo +3 more
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