Results 141 to 150 of about 531,165 (296)

Cancer Regression and Autoimmunity in Patients After Clonal Repopulation with Antitumor Lymphocytes

Science, 2002
M. Dudley, J. Wunderlich, P. Robbins, J. Yang, P. Hwu, D. Schwartzentruber, S. Topalian, R. Sherry, N. Restifo, Amy M. Hubicki, M. Robinson, M. Raffeld, P. Duray, C. Seipp, Linda J. Rogers-Freezer, K. Morton, S. Mavroukakis, D. White, S. Rosenberg   +18 more
semanticscholar   +1 more source

Strategies for Loading and Releasing Peptide Therapeutics in Biodegradable Carriers

Advanced Functional Materials, EarlyView.
A biodegradable carrier‐based peptide delivery system is a powerful treatment platform for diverse diseases, owing to its superior therapeutic efficacy and low toxicity. This review examines the conventional peptide‐loaded carrier fabrication process and its current limitations.
Wookyoung Jang, Ki Wan Bong
wiley   +1 more source

Chronic inflammation-responsive hydrogel restores myeloid-T cell crosstalk to reinvigorate antitumor immunity against metastatic colorectal cancer. [PDF]

Bioact Mater
Li X, Fu W, Le H, Luo R, Li Y, Kou X, He T, Bai L, Xu Y, Cao J, Wang Y, Yu X, Mi P, Luo Z, Gong C.   +14 more
europepmc   +1 more source

MYC regulates the antitumor immune response through CD47 and PD-L1

Science, 2016
S. Casey, Ling Tong, Yulin Li, R. Do, S. Walz, Kelly N Fitzgerald, A. Gouw, V. Baylot, I. Gütgemann, M. Eilers, D. Felsher   +10 more
semanticscholar   +1 more source

Establishing a Model Precursor System: Over a Decade of Research on Carbon Dots from the Citric Acid‐Urea System

Advanced Functional Materials, EarlyView.
The citric acid/urea (CA‐Urea) precursor system offers a versatile, scalable route to carbon dots with tunable luminescence and multifunctionality. Mechanistic insights into precursor chemistry and reaction parameters have enabled doping, surface modification, and hybridization strategies, yielding CDs for luminescent devices, sensing, catalysis ...
Yupeng Liu, Zhiqi Cai, Xiangxin Sun, Hanyi Zhang, Yiming Hao, Jun Wu, Zekun Yan, Xue Wu, Yiqi Liang, Liming Wang, Songnan Qu   +10 more
wiley   +1 more source

A novel strategy for treating oncogene‐mutated tumors by targeting tumor microenvironment and synergistically enhancing anti‐PD‐1 immunotherapy

Cancer Communications
Yingqiang Liu, Linjiang Tong, Mengge Zhang, Qi Zhang, Qiupei Liu, Fang Feng, Yan Li, Mengzhen Lai, Haotian Tang, Yi Chen, Meiyu Geng, Wenhu Duan, Jian Ding, Hua Xie   +13 more
doaj   +1 more source

High‐Throughput Generation of Tumor Spheroids via Droplet Microfluidics for siRNA‐Loaded Nanomedicine Assessment

Advanced Healthcare Materials, EarlyView.
A droplet microfluidic platform is employed to enable high‐throughput, uniform tumor spheroid generation for evaluating siRNA‐loaded nanomedicines at the protein level. As a proof of concept, breast (MCF‐7) and brain (U87 MG) cancer cell lines are investigated using this platform, revealing penetration profiles and therapeutic responses between the two
Ling Liu, Guoying Wang, Yang Zhang, Bingyang Shi, Ming Li   +4 more
wiley   +1 more source

Editorial: Extreme environmental microbial products: Structures, functions, biosynthesis

Frontiers in Microbiology, 2023
Junfeng Wang, Xianwen Yang, Li Liao, Martina Cappelletti, Mirko Basen   +4 more
doaj   +1 more source

Doxorubicin‐Loaded Metal–Organic Framework for Ferroptosis‐Enhanced Chemotherapy Through Sustained Zn Release and Glutathione Peroxidase Downregulation

Advanced Healthcare Materials, EarlyView.
A robust zinc‐based metal–organic framework (ZnMOF) enables dual functions of doxorubicin delivery and sustained Zn2+ release to trigger ferroptosis‐enhnaced chemotherapy. DOX@ZnMOF effectively depletes intracellular glutathione, suppresses GPX4, and elevates reactive oxygen species, leading to efficient oxidative DNA damage and apoptosis.
Xin Ma, Chenghua Deng, Chaoyu Wang, Langston Tilman, Jinhong Li, Wenbin Lin   +5 more
wiley   +1 more source

The critical role of Atpif1 in Her2-targeted CAR-T cell therapy for solid tumor via modulation of metabolism and mtDNA-STING signal pathway. [PDF]

Front Immunol
Zhong G, Liu B, Gong X, Wang Q, Zheng S, Luo X, Chen Z, Zhang X, Hu B, Wu M.   +9 more
europepmc   +1 more source