Results 221 to 230 of about 506,874 (259)
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Antitumor and Antitumor-Promoting Actions of Macrophages and Their Relationship with Estrogen
Oncology, 1996Silica provides, in fact, a remarkable example of selective toxicity for macrophage by a substance of simple chemical composition and low chemical reactivity. Intraperitoneal injection of silica resulted in an increase of growth rate of subcutaneously implanted mouse sarcoma 180 (S180) in female BALB/c mice and of tumor incidence of two-stage mouse ...
Lijian Yu, Rundi Ma, Tingxi Yu
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Synthesis and antitumor activity of analogs of the antitumor antibiotic chartreusin
Journal of Medicinal Chemistry, 1980AbstractDas im Titel genannte Antibioticum (I) wird über (II) und (III) in die Analoga (IV) umgewandelt.
John A. Beisler +2 more
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The antitumor effects of interferon
Medical Oncology and Tumor Pharmacotherapy, 1974Interferons show antitumor activity in patients with various malignancies. The mechanism(s) of the antitumor effects are not altogether clear. In one experimental animal model discussed herein, mice were injected with Friend erythroleukemia cells and treated with mouse interferon alpha/beta.
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Proteomics in antitumor research
Drug Discovery Today: Technologies, 2006Proteins are the molecular players of fine-tuned regulatory pathways that underlie the behavior of any cell type. Derangement of this wide protein circuitry has a profound effect on cell life and ultimately contributes to the development of diseases such as cancer.
FONTANA, Simona +4 more
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Amino Acids, 1994
Chlamydocin is a powerfulin vitro antitumoral agent, quickly inactivatedin vivo. A series of cyclic tetrapeptides related to chlamydocin or HC toxin and bearing a bioactive alkylating group on anε-amino-lysyl function have been examined for their antitumoral activity on L1210 and P388 murine leukemia cell lines.
P. Viallefont +4 more
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Chlamydocin is a powerfulin vitro antitumoral agent, quickly inactivatedin vivo. A series of cyclic tetrapeptides related to chlamydocin or HC toxin and bearing a bioactive alkylating group on anε-amino-lysyl function have been examined for their antitumoral activity on L1210 and P388 murine leukemia cell lines.
P. Viallefont +4 more
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Seminars in Nuclear Medicine, 1976
Bleomycin serves as a useful prototype for a study of the various properties required in a radiopharmaceutical for tumor imaging. Both in vitro and in vivo results using bleomycin labeled with a large number of different radionuclides have now been reported.
C.F. Meares +5 more
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Bleomycin serves as a useful prototype for a study of the various properties required in a radiopharmaceutical for tumor imaging. Both in vitro and in vivo results using bleomycin labeled with a large number of different radionuclides have now been reported.
C.F. Meares +5 more
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Antioxidants as Antitumor Promoters [PDF]
, 1986 Phorbol 12-myristate 13-acetate (PMA) is a potent mouse skin tumor promoter which has been researched most intensively over the years in an attempt to understand the biochemical mechanisms involved in tumor promotion, PMA stimulates a multitude of cellular and biochemical reactions (82), Three of these, induction of ornithine decarboxylase (ODC ...
Walter J. Kozumbo, Peter Cerutti
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Noncytotoxic, Antitumor Polysaccharides
1976Publisher Summary This chapter provides an overview of the available information on host-mediated, antitumor action of noncytotoxic polysaccharides extracted from different botanical sources. Serratia marcescens polysaccharide has been reported to be active against a number of tumors, such as Sarcoma 180, Ehrlich carcinoma, Guerin carcinoma ...
Roy L. Whistler +4 more
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ChemInform Abstract: Bufadienolides and their Antitumor Activity
ChemInform, 2011AbstractReview: 158 refs.
Hui-Min Gao +3 more
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Glycosylation and Antitumor Immunity
2019Glycosylation and its by-product, the glycan, play a crucial role in many cellular processes. Aberrant glycan structures and mutations of the glycosylation pathway have been intricately linked with the development of cancer and more recently with cancer's ability to escape the innate immune system.
Taylor R. Cushman +2 more
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