Results 221 to 230 of about 840,802 (388)

Supplementary Figure 4 from Adjuvant Therapy with Oncolytic Adenovirus Delta-24-RGDOX After Intratumoral Adoptive T-cell Therapy Promotes Antigen Spread to Sustain Systemic Antitumor Immunity

, 2023
Hong Jiang, Dong Ho Shin, Yanhua Yi, Xuejun Fan, Joy Gumin, Jiasen He, Andrew G. Gillard, Frederick F. Lang, Candelaria Gomez‐Manzano, Juàn Fueyo   +9 more
openalex   +1 more source

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source

A selective IDO1 inhibitor, KHK2455, improves efficacy of PD-L1 blockade by modulating both innate and adaptive immunity in a mouse melanoma model. [PDF]

Cancer Immunol Immunother
Saito M, Kunieda K, Ishii T, Koshiba S, Ohashi R, Kanda Y, Yamada T.   +6 more
europepmc   +1 more source

Gemcitabine enhances antitumor efficacy of recombinant lipoimmunogen-based immunotherapy [PDF]

, 2015
Li‐Sheng Chang, Wan-Lun Yan, Yu‐Wen E. Chang, Yi‐Chen Yeh, Hsin–Wei Chen, Chih‐Hsiang Leng, Shih‐Jen Liu   +6 more
openalex   +1 more source

Data from Ncoa2 Promotes CD8⁺ T cell–Mediated Antitumor Immunity by Stimulating T-cell Activation via Upregulation of PGC-1α Critical for Mitochondrial Function

, 2023
Xiancai Zhong, Hongmin Wu, Ching Ouyang, Wencan Zhang, Yun Shi, Yi-Chang Wang, David K. Ann, Yousang Gwack, Weirong Shang, Zuoming Sun   +9 more
openalex   +1 more source

Fluorescent Nanodiamonds Based Theranostic Platform for pH‐Sensitive Drug Delivery and Quantum Sensing

Advanced Functional Materials, EarlyView.
A multifunctional nanodiamond platform enables pH‐triggered Diazoxide (DZX) delivery and quantum sensing of subcellular radical dynamics in triple‐negative breast cancer cells. Diamond relaxometry revealed reduced lysosomal radicals during DZX‐induced mitochondrial radical elevation, providing insights into redox modulation and organelle‐ resolved ...
Kaiqui Wu, Siyu Fan, Yue Zhang, Willem Woudstra, Thomas Mulder, Laurens Boscher Navarro, Jur van Dijken, Katja Loos, Romana Schirhagl   +8 more
wiley   +1 more source

A multicenter, observational study to evaluate the safety of restarting antitumor therapy recovered from COVID-19. [PDF]

Future Oncol
Guo L, Zhou C, Xi W, Yang L, Chang Q, Qu Q, Jiang J, Wu J, Cai Q, Yan J, Wang C, Bi Y, Wen X, Qi F, Zhang J.   +14 more
europepmc   +1 more source

Cyclin E1 overexpression triggers interferon signaling and is associated with antitumor immunity in breast cancer [PDF]

Shibo Yu, Chantal Stappenbelt, Mengting Chen, Matthew Dekker, Arkajyoti Bhattacharya, Tineke van der Sluis, Mieke C. Zwager, Carolien P. Schröder, Rudolf S.N. Fehrmann, Marcel A.T.M. van Vugt, Bert van der Vegt   +10 more
openalex   +1 more source

A human IgG-like bispecific antibody co-targeting epidermal growth factor receptor and the vascular endothelial growth factor receptor 2 for enhanced antitumor activity [PDF]

, 2015
Zhiguo Chen, Wei Xie, Desmond Omane Acheampong, Menghuai Xu, Hua He, Mengqi Yang, Chenchen Li, Chen Luo, Min Wang, Juan Zhang   +9 more
openalex   +1 more source

pH‐Tunable Material Properties of Glycine‐Rich Condensates from Tick Bioadhesive

Advanced Functional Materials, EarlyView.
This work studies the influence of pH on the phase separation behavior of a disordered glycine‐rich protein found in tick bioadhesive. The results show profound impact on the propensity of coacervation, condensate microstructure and viscosity, amphiphilicity of the peptides, and effective encapsulation of therapeutic molecules.
Manali Nandy, Udit Ghosh, Ketan A. Ganar, Hans Ippel, Ingrid Dijkgraaf, Siddharth Deshpande   +5 more
wiley   +1 more source