Results 281 to 290 of about 353,955 (311)
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ChemInform Abstract: Bufadienolides and their Antitumor Activity
ChemInform, 2011AbstractReview: 158 refs.
Hui-Min Gao+3 more
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Noncytotoxic, Antitumor Polysaccharides
1976Publisher Summary This chapter provides an overview of the available information on host-mediated, antitumor action of noncytotoxic polysaccharides extracted from different botanical sources. Serratia marcescens polysaccharide has been reported to be active against a number of tumors, such as Sarcoma 180, Ehrlich carcinoma, Guerin carcinoma ...
Roy L. Whistler+4 more
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Ribonucleases and their antitumor activity
Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, 2001The antitumor effect of ribonucleases was studied with animal ribonucleolytic enzymes, bovine pancreatic RNase A, bovine seminal RNase (BS-RNase), onconase and angiogenin. While bovine pancreatic RNase A exerts a minor antitumor effect, BS-RNase and onconase exert significant effects.
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Antitumor Metabolites of Fungi
Current Bioactive Compounds, 2015The exploitation of the antitumor properties of fungal secondary metabolites is one of the fundamental objectives pursued by a multiplicity of research groups and laboratories working on the characterization of natural products worldwide. The availability of a synthetic framework on such a vast interdisciplinary topic can enhance the current knowledge ...
Nicoletti R, FIORENTINO, Antonio
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Antitumor and Antimicrobial Glycoconjugates
ChemInform, 2001AbstractFor Abstract see ChemInform Abstract in Full Text.
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Initiating an antitumor attack
Science, 2017Cancer Cancer is notorious for relapsing after treatment. Such relapses are driven by tumor-initiating cells, a type of stem cell that gives rise to tumors. Damelin et al. determined that a protein called PTK7 is frequently present on tumor-initiating cells and developed an antibody-drug conjugate targeting it.
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2015
ART acts on tumor cells differentially by the threshold concentrations. High-dose ART kills tumor cells upon the inhibition of NOS, whereas low-dose ART benefits tumor propagation due to induce cytoprotective NO production. Pro-oxidants that antagonize antioxidants can potentiate ART’s antitumor capacity. The combination of ART with pro-oxidants should
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ART acts on tumor cells differentially by the threshold concentrations. High-dose ART kills tumor cells upon the inhibition of NOS, whereas low-dose ART benefits tumor propagation due to induce cytoprotective NO production. Pro-oxidants that antagonize antioxidants can potentiate ART’s antitumor capacity. The combination of ART with pro-oxidants should
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Antitumor Agents Based on Metal–Organic Frameworks
Angewandte Chemie - International Edition, 2021Peng Gao, Yuanyuan Chen, Wei Pan
exaly