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Targeting TMED4 enhances CD8<sup>+</sup> T cell function and CAR T cell efficacy in solid tumors through the IRE1α-autophagy axis. [PDF]

open access: yesSci Adv
Wang H   +20 more
europepmc   +1 more source

T cell-targeting nanoparticles focus delivery of immunotherapy to improve antitumor immunity

open access: green, 2017
Daniela Schmid   +11 more
openalex   +1 more source
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Dihydrochalcones as Antitumor Agents

Current Medicinal Chemistry, 2022
Abstract: Dihydrochalcones are a class of secondary metabolites, possessing several biological properties such as antitumor, antioxidant, antibacterial, antidiabetic, estrogenic, anti-inflammatory, antithrombotic, antiviral, neuroprotective, and immunomodulatory properties; therefore, they are currently considered promising candidates in the drug ...
Fabiola De Luca   +3 more
openaire   +2 more sources

Antitumor Carbazoles

Anti-Cancer Agents in Medicinal Chemistry, 2007
Natural and synthetic carbazoles, either in a pure substituted or in an annellated substituted form, represent an important and heterogeneous class of anticancer agents, which has grown considerably over the last two decades. Many carbazole derivatives have been tested for cyctotoxic activity, some of them have entered clinical trials, but only ...
Asche, Christian, Demeunynck, Martine
openaire   +2 more sources

Antitumor Titanium Compounds

Mini-Reviews in Medicinal Chemistry, 2004
Most anticancer titanium compounds act against tumors in the gastrointestinal tract. Activity towards breast, lung and skin (melanoma) cancers is shown by some as well. Among their appealing properties is that they do not show common side effects of widely used cytostatic agents such as emesis, alopecia or bone marrow impairment.
Caruso Francesco, Rossi Miriam
openaire   +4 more sources

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