Results 121 to 130 of about 928,338 (389)
Multivalent Protein Nanorings for Broad and Potent SARS‐CoV‐2 Neutralization
A protein‐only, modular multivalent nanoscaffold displaying 20 anchor points, decorated with two different binders (10 of each), targeting the SARS‐CoV‐2 receptor‐binding domain is presented. The construct self‐assembles into stable, biocompatible, homogeneous nanoparticles, exhibit synergistic binding with fM IC50 values. It also detects spike at 9 ng
Molood Behbahanipour+11 more
wiley +1 more source
Noroviruses (NoVs) are the main pathogens responsible for sporadic and epidemic nonbacterial gastroenteritis, causing an estimated 219,000 deaths annually worldwide.
Xiaoli Wang+6 more
doaj +1 more source
Role of antiviral therapy in the natural history of hepatitis B virus-related chronic liver disease [PDF]
Hepatitis B virus (HBV) infection is a dynamic state of interactions among HBV, hepatocytes, and the host immune system. Natural history studies of chronic hepatitis B (CHB) infection have shown an association between active viral replication and adverse
Farinati, Fabio+5 more
core +1 more source
A bioelectronic sensor integrating 2D cell membranes with organic microelectrode arrays enables detection of SARS‐CoV‐2 fusion pathways. Natively‐expressed viral receptors promote monitoring of viral entry and screening of antibody‐based inhibitors.
Zixuan Lu+17 more
wiley +1 more source
AN ANTIVIRAL SUBSTANCE FROM PENICILLIUM FUNICULOSUM [PDF]
Richard E. Shope
openalex +3 more sources
The coronavirus disease 19 pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has led to a global health crisis with millions of confirmed cases and related deaths.
Hamlet Khachatryan+11 more
doaj +1 more source
Significance The previous lack of consensus around the use of hydroxychloroquine for COVID-19 patients underlines the need to thoroughly assess the in vivo efficacy of drugs against SARS-CoV-2.
Suzanne J. F. Kaptein+34 more
semanticscholar +1 more source
Peptide coacervates encapsulated with interferon‐α and membranized with metal–phenolic networks (PC‐IFNα@MPNs) are designed to reprogram glucose competition between tumor and cytotoxic T cells. This metabolic modulation enhances immunotherapy by suppressing tumor glycolysis and boosting T cell effector function.
Xin Zheng+17 more
wiley +1 more source
Biological response modifiers (BRMs) have particular promise when used in combination with more standard antiviral agents for treatment of viral diseases.
Robert W Sidwell+6 more
doaj +1 more source
Tarih boyunca viral hastalıklar epidemiler veya pandemiler meydana getirerek, insanoğlunu ve onunla etkileşim halinde olan tüm canlıların yaşamını tehdit etmiştir. Milyonlarca canlının ölümüne veya itlafına yol açan bu salgınlar, korunma ve tedavi gereksinimlerini de beraberlerinde getirmiştir.
KÜÇÜK, Ali, YILDIRIM, Yakup
openaire +3 more sources